Dapsone in a Case with Chronic Recurrent Henoch-Schönlein Purpura |
Jin Choi, Soo Jung Lee, Dae Kyun Koh |
Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea |
Dapsone에 효과를 보인 만성 재발성 Henoch-Schönlein 자반증의 피부병변 1례 |
최진, 이수중, 고대균 |
가톨릭대학교 의과대학 소아과학교실 |
Correspondence:
Soo Jung Lee, Email: 1 |
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Abstract |
The most clearly delineated condition with prominent cutaneous leukocytoclastic vasculitis which presents to a pediatrician is Henoch-Schönlein purpura. There is general agreement that in Henoch-Schönlein syndrome the skin manifestations have a very benign long-term course and that corticosteroids are of little value. Dapsone appears to be of special value in diseases characterized by an accumulation of polymorphonuclear neutrophils notably leukocytoclastic vasculitis. In the pediatric literature, however, no information is available on the use of this sulfone in Henoch- Schönlein purpura.
We report a case of Henoch-Schönlein purpura in a 14-year-old female patient who presented with chronic recurrent skin manifestation and responded to dapsone for two years. |
Key Words:
Henoch-Schö, nlein Purpura, Leukocytoclastic vasculitis, Dapsone |
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