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Cardiovascular Doppler Flow Waveforms in Human Fetuses

Journal of the Korean Pediatric Society 1998;41(12):1639-1649.
Published online December 15, 1998.
Cardiovascular Doppler Flow Waveforms in Human Fetuses
Young Mi Hong
Department of Pediatrics, College of Medicine, Ewha Womans University, Seoul, Korea
도플러 심초음파에 의한 태아 심장판막 혈류속도에 대한 연구
홍영미
이화여자대학교 의과대학 소아과학교실
Correspondence: 
Young Mi Hong, Email: 1
Abstract
Purpose
: Doppler echocardiography has been used to identify fetal cardiac anatomy and hemodynamics. It can estimate flow velocity, volume, and cardiac output. The purpose of this study was to look at cardiovascular waveforms in fetus and to see if there were any changes in Doppler parameter with fetal growth.
Methods
: Blood velocity studies were performed across the mitral, tricuspid, aortic, pulmonic valve, and umblical artery in 124 normal fetuses between 20 and 40 weeks of gestational age.
Results
: Early diastole(E), atrial contraction(A), and the ratio of E to A of mitral and tricuspid valve increased significantly as gestational age advanced, but there was no statistical significance. Mitral and tricuspid velocity were similar. Aortic velocity was significantly higher than pulmonic velocity. Peak velocity, flow integral, Acceleration time(AT), Ejection time(ET) and AT/ET in aorta and pulmonary artery increased significantly as gestational age advanced. Fetal heart rate decreased as gestational age advanced, but there was no statistical significance. Pulsatility index of umblical artery decreased significantly as gestational age advanced.
Conclusion
: Fetal Doppler echocardiography is useful for evaluating fetal cardiac anatomy and cardiovascular function. These normal parameters may be helpful in comparing with fetal congenital heart disease.
Key Words: Fetal echocardiography, Cardiovascular flow waveform


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