Journal of the Korean Pediatric Society 1998;41(5):654-662.
Published online May 15, 1998.
Acute Renal Failure in Children : Underlying Disease and Management according to Age
Eun Joung Park1, Joung Sim Kim1, Jai Bok Yoo2, Joung Sook Sul2, Si Whan Koh1, Phil Soo Oh3, I Suk Kang1, Moon Soo Park1, Heung Jae Lee1, Dong Kyoo Jin1
1Department of Pediatrics, Sung Kyun Kwan University, College of Medicine, Seoul, Korea
2Department of Pediatrics, Sung Kyun Kwan University, College of Medicine, Hemodialysis Room
3Department of Pediatrics Hallym University, College of Medicine, Seoul, Korea
연령에 따른 소아 급성 신부전의 분류와 치료에 대한 고찰
박은정1, 김정심1, 유제복2, 설정숙2, 고시환1, 오필수3, 강이석1, 박문수1, 이흥재1, 진동규1
1성균관대학교 의과대학 삼성서울병원 소아과
2성균관대학교 의과대학 삼성서울병원 투석실
3강남성심병원 소아과
Correspondence: 
Eun Joung Park, Email: 1
Abstract
Purpose
: It has been stressed that age itself as well as multiple organ failure are important prognostic factors in acute renal failure(ARF) in children. This study was performed to find out the significance of age factor and underlying disease of ARF in children.
Methods
: We tried to review 58 pediatric ARF cases, retrospectively, in the pediatric intensive care unit(excluding the neonatal and surgical intensive care unit cases) of the Samsung Seoul Hospital of Sung Kyun Kwan University from Sept., 1994. to Dec., 1996.
Results
: We classified the enrolled 58 cases into 5 age groups and more than half were younger than 1 year old. As underlying causes, heart and gastrointestinal disease were predominant in less than 1 month of age group. After 1 year of age, intrinsic renal disease was the most common cause(43-50%). Among the renal disease, systemic lupus erythematosus(10-15 year group), hemolytic uremic syndrome(1-10 year group), and obstructive uropathy(less than 1 year age group) were common etiologies. The mortality was the highest(46.7%) in less than 1 year group and lowest(21.4%) in 10-15 year age group.
Conclusion
: The underlying disorders of ARF in children were different among the age group. Among intrinsic renal diseases, hemolytic uremic syndrome was the most common cause. The difference in the mortality was dependent on age and underlying disease.
Key Words: Acute renal failure children, Age, Underlying disease, Management


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