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Fetal Cardiac Malformation : types and associated anomalies

Journal of the Korean Pediatric Society 1995;38(6):811-818.
Published online June 15, 1995.
Fetal Cardiac Malformation : types and associated anomalies
Ho Sung Kim1, Jeong Wook Seo2, Chung Il Noh1, Jung Yun Choi1, Yong Soo Yun1
1epartment of Pedeatrics, Seoul National University College of Medicine, Seoul, Korea
2Department of Pathology, Seoul National University College of Medicine, Seoul, Korea
태아 심기형의 유형 및 그와 동반된 다른 장기 기형의 양상
김호성1, 서정욱2, 노정일1, 최정연1, 윤용수1
1서울대학교 의과대학 소아과학교실
2서울대학교 의과대학 병리학교실
: The relative incidence of fetal cardiac anomalies and associated extracardiac anomalies in Korean fetuses were studied.
: Findings in fetal echocardiography and autopsy were reviewed using 129 fetuses with cardiac anomalis detected at a gestational period under 38 weeks from 1991 Jan. to 1994 June.
: The most common fetal cardiac anomaly was isolated atrial septal defect(28 cases : 21.7%). And the ventricular septal defect(19 cases : 14.7%), coartctation of aorta or interruption of arotic arch(16 cases : 12.4%), hypoplastic left heart syndrome(13 cases : 10.1%), tricuspid valve dysplasia including Ebstein's anomaly(8 cases : 6.2%) and pulmonary atresia(7 cases : 5.4%) were common in the order of frequency. Anomalies other than cardiac disease were present in 111 cases(85.2%) and chromosomal anomalies were suspected in 11 cases(8.5%). Common individual anomalies were lung hypoplasia(19 cases : 14.7%), accessory spleen(17 cases : 13.1%), cystic hygroma(15 cases : 11.6%), Meckel's diverticulum(14 cases : 10.9%), single umbilical artery(12 cases : 9.3%) and cleft lip or palate(1 cases : 8.5%) in the order of frequency.
: The frequencies of specific cardiac diseases were different from those in postnatal period. Coarctation on aorta or interruption of aortic arch and hypoplastic left heart syndrome were the 3rd and 4th most common fetal cardiac disease in this study and the result was very different from the previous reports of post-natal cardiac disease. About 85% of the fetuses had associated anomalies and the 60% of the anomalies were potentially lethal. The high frequency of associated anomalies were the result of selection of population or the method of this study which was based largely on autopsy findings.
Key Words: Feral cardiac desease, Fetal echocardiography

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