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EEG Abnormalities in Henoch-Schölein Purpura

Journal of the Korean Pediatric Society 1994;37(11):1600-1606.
Published online November 15, 1994.
EEG Abnormalities in Henoch-Schölein Purpura
Hae Wom Cheon, Dong Gun Park, Kee Hwan Yoo, Joo Won Lee, Soon Kyum Kim
Department of Pediatrics, College of Medicine, Korea University, Seoul, Korea
뇌파이상을보인 Henoch-Schölein Purpura 10례에 관한 연구
전혜원, 박동건, 유기환, 이주원, 김순겸
고려대학교 의과대학 소아과학교실
Schölein-Henoch purpura is a generalized small vessel vasculitis characterized by non-thrombocytopenic purpura, arthritis, abdominal pain and nephritis. In 1913 Osler described an allergic purpura associated with hemiplegia. After then Lewis et al. Reported the cases of Schölein-Henoch purpura associated with convulsion, coma, confusion, intracranial hemorrhage, and chorea, CNS complication has been reported in 1-8% of children and subsided spontaneously in most cases. Headache is a remarkable symptom and appears nonspecific nature. In 1991 Ostergaard and Storm reported that headache occured during the first week following skin rash and frequently showed abnormal EEG findings. We investigated prospectively the presence of a possible cerebral and renal involvement in the case of Schölein-Henoch purpura. EEG abnormality demonstrated in 52.6% of all cases, and headache or irritability in 47.4% of all cases. A significant association was found between abnormal EEG finding and presence of headache, but was not found between EEG findings and presence of renal involvement and hypertension. Patients with abnormal EEG had no past or family history of febrile convulsion or idiopathic epilepsy.
Key Words: Henoch-Schö, lein purpura, Headache, EEG abnormality

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