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A Clinical Observation of Neonatal Hyperbilirubinemia Due to ABO imcompatibility

Journal of the Korean Pediatric Society 1994;37(1):54-60.
Published online January 15, 1994.
A Clinical Observation of Neonatal Hyperbilirubinemia Due to ABO imcompatibility
Kang Woo Lee, Young Guk Kim, Dong Gun Park, Kee Hwan Yoo, Kwang Chul Lee, Soon Kyum Kim
Department of Pediatrics, College of Medicine, Korea University, Seoul, Korea
ABO 부적합군과 적합군에서의 과빌리루빈혈증의 임상적 비교
이강우, 김영국, 박동건, 유기환, 이광철, 김순겸
고려대학교 의과대학 소아과학교실
Abstract
A clinical and statistical study was performed on 213 neonates of hyperbilirubinemia who were admitted to department of pediatrics of Korea University Hospital from Jan. 1989 to Jun. 1991. And we studied the difference between ABO compatible group and incompatible group, such as, day of appe5rance of hyperbilirubinemia, tendency of bilirubin concentration change, reticulocyte, hemoglobin and duration of hyperbilirubinemia. The following results were obtained. 1) There were no difference of initial body weight and gestational age between compatible (3.0¡¾0.72kg, 382. ¡¾3.2weeks) and incompatible groups(3.2¡¾0.54kg, 39.1¡¾2.8weeks). 2) Onset of hyperbilirubinemia within 2days in the imcompatible group (40.5%) was earlier than the compatible group (23.5%) significantly (p<0.05). 3) Mean bilirubin level in the imcompatible gropu was higher than the compatible group significantly (p<0.05). 4) Peak bilirubin level in the imcompatible group (18.7¡¾4.1mg/dl) was higher than the compatible group (14.8¡¾3.4mg/dl) significantly (p<0.05). 5) There were no difference of hemoglobin level, reticulocyte count, coombs positive findings and the ratio of exchange transfusion between two gropus.
Key Words: ABO Incompatibility, Hyperbilirubinemia


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