A Case of Carbamazepine-Induced Toxic Epidermal Necrolysis |
Gi Chan Na, Kyung Seok Kim, Eun Gyeoung Jung, Kyyng Rae Moon, Sang Kee Park, Yeoung Bong Park |
Department of Pediatrics, Collefge of Medicine, Chosun University, Kwang Jum Korea |
Carbamazepine에 의한 중독성 표피괴사 융해증 1례 |
나기찬, 김경석, 정은경, 문경래, 박상기, 박영봉 |
조선대학교 의과대학 소아과학교실 |
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Abstract |
Drug-induced toxic epidermal necrolysis (TEN) is a bullous erythematous disease that is characterized by the appearance of scaled lesions and large sheets of pilling on the skin.
A case of TEN occured in a 10 month old female patient. The characteristic skin lesions of TEN developed after oral administration of carbamazepine for a partial seizure. Thig case consists of prodrome of malaise, fever, anorexia, and conjunctivity followed by erythema & flaccid bullae formation. Diagnosis was confirmed by histologic findings. This patient was treated with a massive systemic corticosteroid, antibiotics, fluid and electrolytes, and topical measures.
Authors experienced an extermely rare case of TEN due to carbamazepine, So report it with a brief review of literature. |
Key Words:
Carbamazepine, Toxic Epidermal Necrolysis |
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