| A Clinical Study of Testicular Relapse in Childhood Acute Lymphocytic Leukemia |
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Hye Ok Roh1, Chuhl Joo Lyu1, Seung Hwan Oh1, Chang Hyun Yang1, Kir Young Kim1, Byung Soo Kim2 |
1Department of Pediatrics, Yonsei University, College of Medicine, Seoul, Korea
2Yonsei Cancer Center, College of Medicine, Seoul, Korea |
| 소아 급성 림프구성 백혈병에서 고환 재발 환아에 대한 임상적 고찰 |
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노혜옥1, 유철주1, 오승환1, 양창현1, 김길영1, 김병수2 |
1연세대학교 의과대학 소아과학교실
2연세대학교 의과대학 연세암센터 |
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| Abstract |
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From January 1984 to June 1991, we studied testicular relapsed patients among 105 cases of acute lymphocytic leukemia in children who were admitted to the Department of Pediatrics and Yonse Cancer Center, Yonsei University Severance Hospital.
The results were as follows:
1) 15 out of 105(14.4%) cases of acute lymphocytic leukemia were diagnosed as testicular relapse. According to the prevalence by the age groups, there were no patient under 2 years old, 14 out of 73(19.4%) in 2~9 years old and 1 out of 26(3.8%) over 10 years old groups.
2) At initial diagnosis of acute lymphocytic leukemia there were significant between testicular relapse and initial lymphadenopathy (p=0.09), but not with WBC count, hemoglobin leverl, platelet count, hepatomegaly and splenomegaly.
3) Mean duration to testicular relapse from initial diagnosis of acute lymphocytic leukemia was 3.1¡¾0.7 years.
4) Mean 15 patients, 7 cases combined with bone marrow or central nervous system relapse. Their survival rate was lower than isolated testicular relapse groups.
5) The 5 years survival rate of testicular relapsed patients was 67% after the combinations of chemotherapy, radiotherapy and orchiectomy. |
| Key Words:
Testicular relapse, Acute lymphocytic leukemia, Childhood |
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