| A Clinical Aspect of the Hemolytic Uremic Syndrome |
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Hye Won Park, Tae Sun Ha, Il Soo Ha, Hae Il Cheong, Yong Choi, Kwang Wook Ko |
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Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea |
| 용혈성 요독 증후군에 관한 임상적 고찰 |
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박혜원, 하태선, 하일수, 정해일, 최용, 고광욱 |
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서울대학교 의과대학 소아과학교실 |
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| Abstract |
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We reviewed the medical records of 14 children (8 girls, 6 boys), diagnosed as hemolytic uremic syndrome at Seoul National University Children뭩 Hospital from 1981 to 1990. The age at presentation ranged from 1 month to 10 years, with a mean age of 2.7 years. Only eight (57.1%) of the children had diarrheal prodrome and five (35.7%) had grossly bloody stool. Oligoanuria developed in eight (57.1%) and gross hematuria in eight (57.1%). Six (42.9%) chlidren had seizures and alteration of consciousness occurred in five (35.7%). In six children (42.9%) serum uric acid levels greater than 15mg/dl were observed. Hypocomplementemia was noted in six (60.0%) of the ten children who had been measured. No organism grew in stool culture for Salmonella and Shigella from 5 diarrheal children.
Overall outcome was poor. Of the 14 children, only five (35.7%) recovered their renal function completely. Hypertension with proteinuria or microscopic hematuria persisted after recovery from renal failure in three (21.4%). Four (28.6%) progressed to end-stage renal disease requiring dialysis and one (7.1%) slowly developed renal insufficiency. One (7.1%) died of acute renal failure. |
| Key Words:
Hemolytic uremic syndrome |
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