Journal of the Korean Pediatric Society 1992;35(5):659-666.
Published online May 15, 1992.
MIC and MBC of Oral Antimicrobial Agents Against Staphylococcus aureus
Min Hang Kim1, Jin Won Park1, Yun Joo Chung1, Kyung Sik Ryoo2, Myung Woong Chang2
1Department of Pediatrics, Kosin Medical College, Pusan, Korea
2Department of Microbiology, Kosin Medical College, Pusan, Korea
경구용 항생제의 Staphylococcus aureus에 대한 MIC와 MBC 검사
김민향1, 박진원1, 정윤주1, 유경식2, 장명웅2
1고신의과대학 의학부 소아과학교실
2고신의과대학 의학부 미생물학교실
Abstract
Antimicrobial susceptibility for 25 stranis of methicillin senitive Staphylococcus (MSSA) and 25 strains of methicillin resistant Staphylococcus aureus (MRSA), isolated from in-patients at Kosin Medical Center from January, 1989 to July, 1990, were tested by the tube dilution method. 1) For MSSA, sensitivity tests showed 21% was sensitive to cefadroxil. Seventy one percent was intermediate and 8% was resistant. 2) 96% of MSSA was sensitive to methicilline, 79% of MSSA was sensitive to oxacillin and 59% of MSSA was sensitive to amoxacillin/clavulanic acid. 3) 92% of MSSA was sensitive to trimethoprim/sulfamethoxazole while 44% of MRSA was sensitive to the drug and 52% was intermediate. 4) All MRSA stains were resistant to methicillin, oxacillin, amoxacillin/clavulanic acid and cefadroxil. 5) Trimethoprim/sulfamethoxazole may be used for MRSA infection.
Key Words: Sensitivity to antibioctics, Staphylococcus aureus


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