All issues > Volume 24(3); 1981

Original Article

J Korean Pediatr Soc. 1981;24(3):229-234. Published online March 15, 1981.

Clinical Obseervation and Changing Patterns of Resistance to Antibiotics in Childhood Shigellosis.

Young Mo Sohn, Kwand Ho Kim, Chang Jun Coe, Pyung Kil Kim, Duk Jin Yun

¹Department of Pediatrics, Colldge of Medicine, Yohsei University Seoul, Korea

Abstract

This paper presents 97 patients of childhood shigellosis which was proved by stool cultures. 44.3% of all patients was accompanied with convulsion. All convulsions were developed under the 6 years of age and associated with high fever. The prognosis was poor in convulsive 容roup. Spinal tapping was performed in 30 patients, in which 3 cases of meningitic type were found. The likelyhood of a convulsion in any given patient was shown to be a funcion of age, hight of body temperature, history of convulsions. Sex and bacterial type and leukocyte count in blood were without effect. Exo toxin and above possible factors may be basic pat-hogenesis in convulsions. Multiple-antibiotic resistance in shigellae was included Ampicillin in recent years, may-be related to the extent of usage of antibiotics, especially in this hospital. The drug of choice is thought to be gentainicine and refamin.

Keywords :Shigellosis