All issues > Volume 26(6); 1983

Case Report

J Korean Pediatr Soc. 1983;26(6):593-597. Published online June 30, 1983.

Cushing'S Syndrome In Childhood.

Duk Hi Kim¹, Nan Ae Kim¹, Do Kwang Yun¹, Duk Jin Yun¹, Eui Ho Hwang²

¹Department of Pediatrics, Yonsei University College of Medicine，Seoul, Korea
²Department of Surgery Yonsei University College of Medicine，Seoul, Korea

Abstract

There are little reports on Cushing’s syndrome in children. We have seen a case of Cushing’s syndrome due to left adrenal adenoma from 5 year 6 months old girl. She has been complained from obesity with, buffalo hump, hirsutism and vaginal spotting. Her blood cortisol levels were high and no diurnal variation. No suppression was occurred following dexamethasone 1 mg overnight or 4 mg daily for 2 days. Huge sized left adrenal mass was visualized by abdominal CT. The tumor was removed successfully by anterior abdominal approach and that was found as a benign adenoma by microscopic study. The literature about Cushing*s syndrome were reviewed.

Keywords :Cortisol; 17 OHCS.; 17 KS; Dexamethasone.