All issues > Volume 47(7); 2004

Case Report

Korean J Pediatr. 2004;47(7):803-806. Published online July 15, 2004.

Bronchiolitis Obliterans Associated with Stevens-Johnson Syndrome

Ko Un KU Chun¹, Soo S Yun¹, Byung Ho BH Cha¹, Hae Yong HY Lee¹

¹Department of Pediatrics, Wonju College of Medicine, Yonsei University, Wonju, Korea

Correspondence Hae Yong HY Lee ,Email: leehy@wonju.yonsei.ac.kr

Abstract

Bronchiolitis Obliterans(BO) is one of the rare inflammatory lung disease that primarily affects bronchi and bronchioles, followed by partial or complete obstruction. In children, the etiology of BO has been under consideration, but infections and toxic inhalation, connective tissue diseases, lung transplantation, congestive pulmonary edema, etc., may be causes of BO. Even though steroid therapy was reported as an effective treatment, there are few data regarding the epidemiology, pathophysiology, long term prognosis and therapy. Here we describe a 5-year-old boy who presented with intractable wheezing associated with Stevens-Johnson syndrome after Varicella-Zoster virus infection and was diagnosed as BO through chest high-resolution computed tomography.

Keywords :Bronchiolitis obliterans, Stevens-Johnson syndrome, Herpesvirus 3, Human