All issues > Volume 37(4); 1994

Case Report

J Korean Pediatr Soc. 1994;37(4):553-559. Published online April 15, 1994.

Furosemide-Induced Nephrocalcinosis in Very Low Birth Weight Infants

Abstract

Renal calcifications are a recognized complication of furosemide therapy in premature infants. Particularly in infants with chronic lung disease, the use of this potent diuretic is associated with hypercalciuria, which may predispose the infant to medullary nephrocalcinosis and renal calculi. We experienced two cases of nephrocalcinosis in very low birth weight infants. One had bronchopulmonary dysplasia, pneumonia, patent ductus arteriosus, ventricular septal defect and congestive heart failure and the other had systemic cytomegalovirus infection with cytomegalovirus pneumonitis and ricket of prematurity. Both patients received a large amount of furosemide. We presented these cases with brief review of literatures.

Keywords :Furosemide, Nephrocalcinosis, Very low birth weight infant