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Case Report
Infection
Acute pancreatitis in hand, foot and mouth disease caused by Coxsackievirus A16: case report
Byungsung Park, Hyuckjin Kwon, Kwanseop Lee, Minjae Kang
Clin Exp Pediatr. 2017;60(10):333-336.   Published online October 20, 2017

Coxsackievirus A16 (CA16), which primarily causes hand, foot, and mouth disease (HFMD), is associated with complications, such as encephalitis, acute flaccid paralysis, myocarditis, pericarditis, and shock. However, no case of pancreatitis associated with CA16 has been reported in children. We report a case of CA16-associated acute pancreatitis in a 3-year-old girl with HFMD. She was admitted because of poor oral...

Massive pulmonary hemorrhage in enterovirus 71-infected hand, foot, and mouth disease
Dong Seong Lee, Young Il Lee, Jeong Bae Ahn, Mi Jin Kim, Jae Hyun Kim, Nam Hee Kim, Jong Hee Hwang, Dong Wook Kim, Chong Guk Lee, Tae Won Song
Clin Exp Pediatr. 2015;58(3):112-115.   Published online March 20, 2015

Hand, foot, and mouth disease (HFMD) is an acute, mostly self-limiting infection. Patients usually recover without any sequelae. However, a few cases are life threatening, especially those caused by enterovirus 71 (EV71). A 12-month-old boy was admitted to a primary hospital with high fever and vesicular lesions of the mouth, hands, and feet. After 3 days, he experienced 3 seizure...

Original Article
Enterovirus 71-associated hand, foot and mouth diseases with neurologic symptoms, a university hospital experience in Korea, 2009
Hye Kyung Cho, Na Yong Lee, Hyunju Lee, Hae Soon Kim, Jeong Wan Seo, Young Mi Hong, Seung Joo Lee, Sun Wha Lee, Doo Sung Cheon, Ji Young Hong, Byung Hak Kang, Jong-Hyun Kim, Kyung-Hyo Kim
Clin Exp Pediatr. 2010;53(5):639-643.   Published online May 31, 2010
Purpose

Hand-foot-mouth disease (HFMD) is a common viral illness in children, which is usually mild and self-limiting. However, in recent epidemics of HFMD in Asia, enterovirus 71 (EV71) has been recognized as a causative agent with severe neurological symptoms with or without cardiopulmonary involvement. HFMD was epidemic in Korea in the spring of 2009. Severe cases with complications including death have...

Review Article
Enterovirus 71 infection: An experience in Korea, 2009
Kyung Hyo Kim
Clin Exp Pediatr. 2010;53(5):616-622.   Published online May 31, 2010

Enterovirus 71 (EV71) has been recognized as a frequent cause of epidemics of hand-foot-and-mouth disease (HFMD) associated with severe neurological symptoms. In the spring of 2009, HFMD was epidemic in Korea. Severe cases with complication, including death, have been reported and it has become a public health issue. Most symptomatic EV71 infections commonly result in HFMD or herpangina. These clinical...

Case Report
Hand-Foot syndrome induced by sorafenib, a multitargeted tyrosine kinase inhibitor, in a patient with advanced renal cell carcinoma
Seung Hyun Lee, Sung Hun Noh, Sun Young Kim, Kyu Yun Jang, Pyoung Han Hwang
Clin Exp Pediatr. 2009;52(1):119-123.   Published online January 15, 2009
Renal cell carcinoma (RCC) arising from epithelial cells of the renal tubules is a highly aggressive and malignant tumor in all ages; however, it rarely occurs in children. the standard treatment for RCC is radical nephrectomy with lymph node dissection when the tumor is localized and can be completely resected. Adjuvant chemotherapy, radiotherapy, and immunotherapy are used for pediatric patients...
Original Article
Health Assessment of Handicapped Children in an Asylum
Eun Ju Lee, Eun Sil Lee, Han Ku Moon, Yong Hoon Park, Son Moon Shin
Clin Exp Pediatr. 2000;43(9):1263-1268.   Published online September 15, 2000
Purpose : To evaluate the health status of institutionalized handicapped children, a general health assessment was done in an asylum in Taegu in May 1998. Methods : Body measurements, including height, weight, head circumference, skin fold thickness and mid-arm circumference, were done with physical examination on 53 children. Blood tests and chest radiography were done, and fat impedance was measured....
Case Report
A Case of Split Hand Split Foot Anomaly
Mi Do Lee, Byung Moon Ahn, Moo Young Song, Eun Ryoung Kim, Mi Wook Jin, Il Soo Kim
Clin Exp Pediatr. 1999;42(7):1008-1013.   Published online July 15, 1999
We experienced a case of split hand split foot(SHSF) anomaly in a male neonate who had a deficiency of the middle finger, syndactyly of the 1st and 2nd finger and a deep median cleft in both hands. He also had a deep median cleft between 2nd and 3rd toe, syndactyly of the 1st and 2nd, 3rd and 4th toe without...
Original Article
Meta-analysis of Impact of Neonatal Intensive Care on Neurodevelomental Outcome of Very Low Birth Weight Infants
Beyong Il Kim, Jung-Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1994;37(7):937-945.   Published online July 15, 1994
We analyzed neurodevelopmental outcome data of 36 selected studies. Data of individual studies were pooled by birth weight group: <800g, <1,000g, <1,500g and by time period of birth year: Period I(pre-intensive care era), 1960-67:Period II(beginning period of intensive care), 1968-76:and Period III(established period of intensive care), 1977-87. In all weight groups, survival and intact outcome rates based on live birth have...
Hand, Foot and Mouth Disease Associated with the Aseptic Meningitis in Seoul, 1990
Young Ah Lee, Sei Ho Oh, Soo Jong Hong, Young Hwue Kim, Hyung Nam Moon, Chang Yee Hong
Clin Exp Pediatr. 1993;36(6):842-849.   Published online June 15, 1993
We performed clinical and virological studies on 79 children with hand, foot and mouth disease(HFMD) who had been admitted or visited to the department of Pediatrics, Asan Medical Center from February to August, 1990. The results were as follows; 1) There were total of 79 cases with hand, foot and mouth disease during this period. The aseptic meningitis was combined in 18cases(22.8%) 2)...
Predictors of neurologic handicap in hypoxic ischemic encephalopathy.
Seung Tae Kim, Gui Ran Kim, Byung Hak Lim, Sang Geel Lee, Im Ju Kang
Clin Exp Pediatr. 1991;34(4):473-479.   Published online April 30, 1991
Retrospective follow up studies were done in 52 term infants who were treated at the nursery in Taegu Fatima Hospital, for clinical evidence of Hypoxic ischemic enecphalopathy (stage II). All children were followed for a minimum of 6 months. Factors that significantly correlated with prognosis included 5-minute Apgar scores, the age at the onset of the seizures, the EEG and the initial brain CT. (1) Of...
Case Report
Two Cases of Hand-Schuller-Christian Disease in Monozygotic Twin.
Pyoun Han Hwang, Ju Hyung Kim, In Soo Choi, Jung Soo Kim
Clin Exp Pediatr. 1985;28(1):85-89.   Published online January 31, 1985
Authors experienced two cases of Hand-Schuller-Christian disease developed simultaneously in 35 month old male monozygotic twin. So we report with literature review briefly as follow. The elder had the complaints of polyuria, exophthalmos, skin lesion. The younger had the complaints of mild exophthalmos and skin lesion. They were confirmed by clinical and pathological features and radiological examination. But patients died...
A Case of Histiocytosis X(Hand-Schuller-Christian Syndrome).
Yeong Bong Park, Jin Heon Kim, Jong Myeon Hong, Chang Soo Ra
Clin Exp Pediatr. 1983;26(12):1209-1214.   Published online December 31, 1983
A case of histiocytosis X (Hand-Schuller-Christian syndrome) in a 3 year old girl is presented. The patients has the triad of exophthalmos, diabetes insipidus and skeletal lesions, plus hepatomegaly, wide spread pulmonary infiltration and growth retardation. The patient was treated with chlorambucil, prednisone, radiation therapy and chlorpropamide therapy for diabetes insipidus with good response. Similar cases reported in literature are briefly...
A Case of Hand Schuller Christian Disease.
Yeon Saeng Lee, Soo Young Kim, So Kyung Park, Dong Hak Shin
Clin Exp Pediatr. 1983;26(4):392-396.   Published online April 30, 1983
Hand-Schuller-Christian disease is reactive granulomatous lesion with histiocytic proliferation, the cause of which is unknown. Recently, we experienced a case in a 3 years old female with polydipsia and polyuria. We established the diagnosis with clinical features, radiologic examination and bone biopsy- Histiologic examination of frontal bone showed mild to moderate infiltration of eosinophils, lymphocytes, plasma cells and large histioytes and fibrosis. Similiar cases reported in...
Original Article
Clinical Study of Hand, Foot, and Mouth Disease and Herpangina.
Tae Hoon Lee, Jae Ock Park, Chang Hwi Kim, Dong Whan Lee, Sang Man Shin, Sang Jhoo Lee
Clin Exp Pediatr. 1983;26(1):14-25.   Published online January 31, 1983
A total of 211 children fullfilling all characteristics of Hand, Foot, and Mouth disease (H.F.,& M. Dis.) and 94 children of Herpangina were studied prospectively during epidemic period of 5 months, April through August, 1981 in Seoul, Korea. Maculopapular rash and vesicles that were changed in patterns from time to time were distributed on hands(97%), feet(95%), buttocks(46%), legs(45), arms(16%), trunk (3%),...
Anemia in the Metal and Physical Handicapped.
Jeong Sik Min, Chan Il Ahn
Clin Exp Pediatr. 1982;25(7):687-698.   Published online July 31, 1982
Nutrition is thought to be much more important to the handicapped for their growth and development and successful management of their disease because they have much more complexed problems in physical, emotional, familial, and socioeconomic aspects. The authors determined number of erythrocytes and leukocytes, quantity of hemoglobin, hematocrit, reticulocyte, number of platelets for the survey of anemia to evaluate the...
Clinical Diagnosis of Mental Handicap Child and Their Assessment.
Chang Jun Coe
Clin Exp Pediatr. 1981;24(10):911-919.   Published online October 15, 1981
140 cases of mentally handicapped children were investigated for clinical diagnosis and assessed for their abilities by Griffith test. The youngest child was 1 month old and the oldest was 15 years old. The clinical diagnosis was able to make in 75%: 40% was cerebral palsy and the rest 35% showed various diagnosis. In 25%, etiological diagnosis was not able...
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