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Vitamin D-Resistant Rickets

Journal of the Korean Pediatric Society 1968;11(6):321-328.
Published online June 30, 1968.
Vitamin D-Resistant Rickets
H.W. Kim, D.H. Bang, K.R. Kwak, K.S. Lee
Department of Pediatrics, National Medical Center
Vitamin D-Resistant Rickets
金顯宇, 方斗憲, 郭景魯, 李護洙
國立醫療院 小兒科
Abstract
Six cases of vitamin D resistant rickets are reported in Korean children, and comprehensive summary of clinical features and brief review of literatures are involved in this article. Two cases of them (15 and 7 years old boys respectively) were typical Fanconi syndrome with marked stunted growth, walking difficulty and valgus deformities in association with hypophosphatemia, renal glycosuria, marked aminoaciduria, hyperphosphaturia and proteinuria, which had been published already on JKMA, 11:61,1968. Other 4 cases are primary vitamin D resistant rickets, and clinical, biochemical and radiological remission after massive vitamin D therapy (60, 000-450,000 U. daiy) are seen. There is no evidence of hereditary inheritences in history in our cases.


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