Journal of the Korean Pediatric Society 1967;10(12):647-652.
Published online December 31, 1967.
Disseminated Aspergillosis(An Autopsy Case of a Child with Liver Cirrhosis)
S.K. Lee1, J.G. Chi1, H.S. Park1, Y. J. Kwon2, Y.W. Hong2, B.H. Rie2
1Dept, of Pathology, College of Medicine, Seoul National University
2Dept, of Pediatrics, College of Medicine Seoul National University
全身性Aspergillosis 一肝硬變症을 隨伴한 小兒의 1 部檢例-
李尙園1, 池提根1, 朴孝淑1, 樓奉 助2, 洪鎔宇2, 李炳勳2
1서울大學校 醫科大學 病理學敎室
2서울大學校 醫科大學 小兒科學敎室
Abstract
An autopsy case of disseminated aspergillosis in a 11 years and 9 months old Korean male has been reported. The patient was managed with broad spectrum antibiotics through the hospital stays of two times for liver cirrhosis. At autopsy non-specific granulomatous or suppurative lesions were found in the lungs, endocardium, kidney, thyroid and brain. Microscopically, areas of necrosis with numerous branching mycelia were present in all the lesions of the viscera. These were widespread infarcts of the brain, with invasion of thrombi and blood vessels by the fungi. Morphologically the fungi were composed of inumerable hyphae having true septation and branching of acute angle. Chlamydospores and conidiospores were also frequently observed in the lesions.




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