Journal of the Korean Pediatric Society 1973;16(6):479-485.
Published online June 30, 1973.
Statistical Observation of Hemolytic Streptococcal Infections
Bang Sup Lee, Young Koo Yeo, Hong Yul Lee, Sung Hoon Cho
Department of Pediatrics, Catholic Medical College Seoul, Korea
용연균 감염의 통계적 고찰
이방섭, 여영구, 이홍열, 조성훈
가톨릭 의 과대학 소아과학교실
Auther observed statistically 302 cases of hemolytic streptococcal infections in Korean children who had admitted to Dept, of Ped., St. Mary’s Hospital from Jan. 1966 to June 1972. The results were as follows: 1)The incidence of streptococcal infections in 4,739 hospitalized sick children was 6.3%. Among 302 cases, 176 cases (59.2%) were female. The annual incidence was highest in 1966 (8.9%). 2)In these streptococcal infections, the incidences of acute glomerulonephritis, rheumatic fever and streptococcal sore throat were 200 cases (66.2), 35 cases (11.6%), 12 cases (4.0%),respectively. 3)The average ages of the onset of acute glomerulonephritis, rheumatic fever, streptococcal pharyngitis and scarlet fever were at the age of 7 to 9 years, 7 to 12 years, under the age of 6, and at the age of 4 to 6 years respectively. 4) Seasonal incidence of the streptococcal infections was more prominent from September to February through a year. 5)Most common preceding infections in acute glomerulonephritis and rheumatic fever was upper respiratory infections, and the incidences were 56% and 27.2% respectively. The initial symptoms of acute glomerulonephritis developed most frequently at second week (51.3%), whereas the initial symptoms of rheumatic fever developed most frequently over 4 weeks (50%) after preceding infections. 6)Laboratory findings: In acute glomerulonephritis, elevated E.S.R in 64.5% of cases, leucocytosis in 43.6% of cases, A-SO titer over 333 units in 46.5% of cases arid positive CRP in 15.5% of cases were found. In rheumatic fever, elevated ESR in 61.8% of cases, leucocytosis in 43.6% of cases, ASO titer over 333 units in 63.7% of cases and positive CRP in 48.2% of cases were found. On scarlet fever, elevated ESR in 83.4% of cases, leucocytosis in 100% of cases, ASO titer under 250 units in 100% of cases and positive CRP in 35% of cases were found. 7)The frequency of positive culture of beta-hemolytic streptococcus by throat swab in acute glome-rulonephritis, rheumatic fever and scarlet fever were obtained in 20 cases (33.9%) out of 59 cases, in 4 cases (28.6%) out of 14 cases, in 5 cases, in 5 cases (41.7%) out of 12 cases, in 4 cases (80%)out of 5 cases, respectively.

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