Journal of the Korean Pediatric Society 1981;24(8):752-759.
Published online August 15, 1981.
Hashimoto's Thyroiditis in childhood.
Hee Jung Chung1, Back Keun Lim1, Duk Hi Kim1, Duk Jin Yun1, Chan Il Park2
1Department of Pediatrics, College of Medicine yonsei University, Seoul, Korea.
2Department of Pathology, College of Medicine yonsei University, Seoul, Korea.
소아연령의 만성 임파구성 갑상선염에 관한 임상적 고찰
정희정1, 임백근1, 김덕희1, 윤덕진1, 박찬일2
1연세의대 소아과학 교실
2연세의대 병리학교실
Abstract
Serum levels of T3, T4, TSH, 24-h RAIU and Thyroid antibodies were examined in 13 cases of chronic lymphocytic thyroiditis who were diagnosed at the pediatric department of Yonsei University hospital during the period from 1978 to 1980. The results were as follows: 1. The age distribution was dispersed between 8 and 15 years of age and all the cases were female. 2. Common symptoms were Goiter, Poor Weight gain, fatigness, cold intolerance, lethargy, constipation and cold sweating. But in 5 cases(38%), there were no subjective symptoms. 3. The patients were classifed by their thyroid function state, as 1 case of hyperthroid group, 10 cases of euthyroid group, and 2 cases of hypothyroid group. 4. In the Euthyroid patients, Serum T3 concentration was 115-230ng/100ml)mean 167.4ng/100ml), T4 concentration 4.8-18.6microgram/100ml(mean 7.3 microgram/100ml) T3/T4 ratio 0.020-0.028(mean 0.024) and TSH was 37-60microU/ml(mean 49.5microU/ml). In the hyperthyroid patient, serum T3 concentration was 310ng/100ml. T4 concentration 14.9microgram/100ml, T3/T4 ratio 0.020 and TSH was 1.35microU/ml. 5. In 24-h RAIU, Euthyroid patients were in 2 cases of decreased state(15%), 2 cases of normal range (15~45%), and 6 cases of increased state(45%). All Hypothyroid patients were in normal range and hyperthyroid patient was in increased state. 6. Thyroglobulin antibody was positive in all the patients except 2 cases and microsomal antibody was positive in all the cases. 7.1 year of follow up study was performed in 4 cases of euthyroid patients, 1 case of hyperthroid patient, and 2 cases of hypothroid patients. There was no euthyroid patient who became hypothyroid state in the follow up study.
Key Words: hashimoto's thyroiditis, clinical investigation, follow up




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