Journal of the Korean Pediatric Society 1989;32(6):816-822.
Published online June 30, 1989.
Clinical Observation and Electroencephalographic Findings relatee to Prognostic factor in Neonatal Seizure.
Soo Chun Kim, Jung Sam Jeon, Chong Woo Bae, Sa Joon Chung, Chang Il Ahn
Department of Pediatrics, College of Medicine, Kyung Hee University, Seoul, Korea
신생아 경련의 임상 및 예후인자로서 뇌파소견의 고찰
김수천, 전정삼, 배종우, 정사준, 안창일
경희대학교 의과대학 소아과학교실
Received: 27 October 1988   • Accepted: 9 December 1988
To study the clinical prognosis of the neonatal seizure, we carried out a retrospective review on medical records of 40 neonates who were admitted to the Dept. of Pediatrics, Kyung Hee University Hospital between January 1979 and December 1986. The results from the study are summarized as follows 1) Male to female ratio were 1.8:1. In 50.0%(20/40) of newborn infants, neonatal seizure was detected under 7 days of age, in 17.5% by 21 days of age, in 32.5% by 28 days of age. 2) The etiologic classifications of neonatal seizure were hypoxic ischemic encephalopathy (18 cases, 45%), hypocalcemia (7 cases, 17.5%), intracranial hemorrhage (6 cases, 15%), developmental defect (4 cases, 10%), infection (3 cases, 7.5%) and hypoglycemia (2 cases, 5.0%). 3) Neonatal seizures may be classified into several types including generalized tonic (17 cases, 42. 5%), subtle (12 cases, 30%), multifocal clonic (4 cases, 10%), focal clonic (4 cases, 10%) and myoclonic attacks (3 cases, 7.5%). 4) The EEG findings were abnormal in 19 cases (47.5%). 5) In relapsing cases (10 cases, 25%), male to female ratio were 0.4: 1. 6) According to etiologic classification, relapsing rates were 100% in developmental defect, 33.3% in intracranial hemorrhage and infection, 16.7% in hypoxic ischemic encephalopathy. 7) In relapsing cases, the EEG findings was abnormal in 9 cases (90.0%).
Key Words: Neonatal seizure, Prognosis, EEG

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