Journal of the Korean Pediatric Society 2002;45(6):712-718.
Published online June 15, 2002.
Analgesic Effect of Sugar Solution in Infantile Colic
Jong Seok Kim, Kyung Ho Kwon, Young A Lee, Hyeon Jeong Kim, Kyun Woo Lee
Department of Pediatrics, Dae Dong Hospital, Pusan, Korea
설탕물이 영아 산통의 통증 감소에 미치는 영향
김종석, 권경호, 이영아, 김현정, 이균우
부산대동병원 소아과
Correspondence: 
Jong Seok Kim, Email: jomany@freechal.com
Abstract
Purpose
: Infantile colic is one of the most commonly encountered problems, characterized by excessive crying in apparently healthy young infants within the first 3 months of life. It is commonly assumed that the infant with colic has distress and possible pain. In recent investigations, it has been found that sucrose has an analgesic effect in newborn infants. The purpose of this study is to examine if sugar solution as sucrose also has an analgesic effect on infant colic.
Methods
: This prospective randomized, double-blind placebo controlled study examined healthy term infants aged 4 to 12 weeks with colic. A total of 40 infants were randomly assigned into two groups who visited Daedong Hospital from June 1999 to June 2001. Each group received sugar solution or sterile water. All data from parental diaries and interviews were recorded and analysed blindly.
Results
: The daily crying time and the colic improvement score were significantly better in sugar solution group as compared with the control(P=0.019, 0.045). No significant differences were noted between groups regarding the number of night wakenings(P=0.173).
Conclusion
: We conclude that sugar solution has an analgesic effect on infantile colic.
Key Words: Infantile colic, Analgesic effect, Sucrose, Sugar solution


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