| Usefulness of Brain Tc-99m HMPAO SPECT in Establishing Lateralization of Intractable Seizure in Children |
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Suck-Hee Ahn1, Young-Ho Rah1, Sa-Jun Chung1, Eu-Hyun Cho2 |
1Department of Pediatrics, College of M edicine, Kyunghee University, Seoul, Korea
2Chungju Medical Center, Korea |
| 난치성 간질환아의 간질병소 편측화 진단에서 뇌 Tc-99m HMPAO SPECT 검사의 유용성에 관한 연구 |
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안석희1, 나영호1, 정사준1, 조의현2 |
1경희대학교 의과대학 부속병원 소아과
2청주의료원 |
Correspondence:
Sa-Jun Chung, Email: 1
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| Abstract |
Purpose
: To determine the role of Tc-99m HMPAO SPECT imaging in children with intractable seizure by evaluating the interictal period.
Methods
: We compared the EEG, CT and MRI medical records with those of Tc-99m HMPAO
SPECT in 42 patients with intractable seizure referred to Kyunghee University Hospital, from April 1983 to September 1998, retrospectively.
Results
: Mean age was 8.3 years and male to female ratio was 2.5 : 1. Multiple surface EEG recordings were performed in 42 patients and EEG findings of all patients showed an epileptogenic focus, with the most common area of abnormal findings being the Lt. sides. Brain CT was performed in 23 out of 42 patients(54.8%), and 15 out of the 23 patients(65.2%) showed abnormal findings and the most common area of abnormal findings were both sides. Brain MRI was performed in 21 out of 42 patients(50.0%), and 14 of the 21 patients(66.6%) showed abnormalities and the most common area of abnormal findings were both sides. In 32 out of the 42 patients (76.2%), SPECT images showed abnormal cerebral perfusion, most common area of hypoperfusion were Lt. sides. In 10 out of 14 cases, there were lateralizing abnormalities on the same side shown in SPECT and EEG, CT or MRI findings.
Conclusion
: We concluded that Tc-99m HMPAO SPECT seemed to be a useful tool in the
evaluation of intractable seizure patients. |
| Key Words:
Tc-99m HMPAO SPECT, Intractable seizure, Lateralization |
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