- Review Article
- Nutritional aspect of pediatric inflammatory bowel disease: its clinical importance
- Seung Kim, Hong Koh
- Clin Exp Pediatr. 2015;58(10):363-368. Published online October 21, 2015
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Inflammatory bowel disease (IBD) is a chronic inflammatory disease mainly affecting the gastrointestinal tract. The incidence of the disease is rapidly increasing worldwide, and a number of patients are diagnosed during their childhood or adolescence. Aside from controlling the gastrointestinal symptoms, nutritional aspects such as growth, bone mineral density, anemia, micronutrient deficiency, hair loss, and diet should also be closely...
- Original Articles
- Diagnostic characteristics of supplemental laboratory criteria for incomplete Kawasaki disease in children with complete Kawasaki disease
- Hyun Ok Jun, Jeong Jin Yu, So Yeon Kang, Chang Deok Seo, Jae Suk Baek, Young-Hwue Kim, Jae-Kon Ko
- Clin Exp Pediatr. 2015;58(10):369-373. Published online October 21, 2015
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Purpose In 2004, the American Heart Association (AHA) had published an algorithm for the diagnosis of incomplete Kawasaki disease (KD). The aim of the present study was to investigate characteristics of supplemental laboratory criteria in this algorithm.
Methods We retrospectively examined the medical records of 355 patients with KD who were treated with intravenous immunoglobulin (IVIG) during the acute phase of the disease....
- Uveitis as an important ocular sign to help early diagnosis in Kawasaki disease
- Han Seul Choi, Seul Bee Lee, Jung Hyun Kwon, Hae Soon Kim, Sejung Sohn, Young Mi Hong
- Clin Exp Pediatr. 2015;58(10):374-379. Published online October 21, 2015
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Purpose Incomplete Kawasaki disease (KD) is frequently associated with delayed diagnosis and treatment. Delayed diagnosis leads to increasing risk of coronary artery aneurysm. Anterior uveitis is an important ocular sign of KD. The purpose of this study was to assess differences in laboratory findings, including echocardiographic measurements, clinical characteristics such as fever duration and treatment responses between KD patients with and...
- Clinical characteristics of children and adolescents with croup and epiglottitis who visited 146 Emergency Departments in Korea
- Doo Ri Lee, Chang Hyu Lee, Youn Kyung Won, Dong In Suh, Eui-Jung Roh, Mi-Hee Lee, Eun Hee Chung
- Clin Exp Pediatr. 2015;58(10):380-385. Published online October 21, 2015
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Purpose Croup is a common pediatric respiratory illness with symptoms of varying severity. Moreover, epiglottitis is a rare disease that can rapidly progress to life-threatening airway obstruction. Although the clinical course and treatments differ between croup and epiglottitis, they are difficult to differentiate on presentation. We aimed to compare the clinical characteristics of croup and epiglottitis in Emergency Department patients.
Methods The 2012...
- Prognostic factors in children with extracranial germ cell tumors treated with cisplatin-based chemotherapy
- Jinsup Kim, Na Hee Lee, Soo Hyun Lee, Keon Hee Yoo, Ki Woong Sung, Hong Hoe Koo, Jeong-Meen Seo, Suk-Koo Lee
- Clin Exp Pediatr. 2015;58(10):386-391. Published online October 21, 2015
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Purpose To evaluate the outcomes and prognostic factors in children with extracranial germ cell tumors (GCTs) treated at a single institution.
Methods Sixty-six children diagnosed with extracranial GCTs between 1996 and 2012 were included in the study. Primary treatment was surgical excision, followed by six cycles of cisplatin-based chemotherapy. The survival rates were compared according to the International Germ Cell Cancer Cooperative Group...
- Alagille syndrome and a
JAG1 mutation: 41 cases of experience at a single center - Kyung Jin Ahn, Ja Kyoung Yoon, Gi Beom Kim, Bo Sang Kwon, Jung Min Go, Jin Su Moon, Eun Jung Bae, Chung Il Noh
- Clin Exp Pediatr. 2015;58(10):392-397. Published online October 21, 2015
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Purpose Alagille syndrome is a complex hereditary disorder that is associated with cardiac, hepatic, skeletal, ocular, and facial abnormalities. Mutations in the Notch signaling pathway, such as in
JAG1 andNOTCH2 , play a key role in embryonic development. A cardiac or hepatic presentation is a critical factor for determining the prognosis.Methods We conducted a retrospective study of 41 patients with Alagille syndrome...
- Case Reports
- The first pediatric case of tularemia in Korea: manifested with pneumonia and possible infective endocarditis
- Jung Sook Yeom, Kyuyol Rhie, Ji Sook Park, Ji-Hyun Seo, Eun Sil Park, Jae-Young Lim, Chan-Hoo Park, Hyang-Ok Woo, Hee-Shang Youn
- Clin Exp Pediatr. 2015;58(10):398-401. Published online October 21, 2015
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Tularemia is a potentially severe zoonotic disease caused by
Francisella tularensis . A lack of awareness about tularemia can be embarrassing and could result in delayed treatment because of improper diagnosis. The diagnosis of tularemia is difficult, because the infections are rare and the clinical spectrum is broad. As only 1 adult case has been reported in Korea thus far, pediatricians...
- Plasmaphresis therapy for pulmonary hemorrhage in a pediatric patient with IgA nephropathy
- Dae-Kyoon Yim, Sang-Taek Lee, Heeyeon Cho
- Clin Exp Pediatr. 2015;58(10):402-405. Published online October 21, 2015
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IgA nephropathy usually presents as asymptomatic microscopic hematuria or proteinuria or episodic gross hematuria after upper respiratory infection. It is an uncommon cause of end-stage renal failure in childhood. Pulmonary hemorrhage associated with IgA nephropathy is an unusual life-threatening manifestation in pediatric patients and is usually treated with aggressive immunosuppression. Pulmonary hemorrhage and renal failure usually occur concurrently, and the...