- Review Articles
- Noninvasive diagnosis of pediatric nonalcoholic fatty liver disease
- Hye Ran Yang
- Clin Exp Pediatr. 2013;56(2):45-51. Published online February 25, 2013
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Because nonalcoholic steatohepatitis can progress towards cirrhosis even in children, early detection of hepatic fibrosis and accurate diagnosis of nonalcoholic fatty liver disease (NAFLD) are important. Although liver biopsy is regarded as the gold standard of diagnosis, its clinical application is somewhat limited in children due to its invasiveness. Noninvasive diagnostic methods, including imaging studies, biomarkers of inflammation, oxidative stress,...
- Cardiomyopathies in children
- Young Mi Hong
- Clin Exp Pediatr. 2013;56(2):52-59. Published online February 25, 2013
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Cardiomyopathy (CMP) is a heterogeneous disease caused by a functional abnormality of the cardiac muscle. CMP is of 2 major types, dilated and hypertrophic, and is further classified as either primary or secondary. Secondary CMP is caused by extrinsic factors, including infection, ischemia, hypertension, and metabolic disorders. Primary CMP is diagnosed when the extrinsic factors of secondary CMP are absent....
- Bone mineral density deficits in childhood cancer survivors: Pathophysiology, prevalence, screening, and management
- Min Jae Kang, Jung Sub Lim
- Clin Exp Pediatr. 2013;56(2):60-67. Published online February 25, 2013
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As chemotherapy and other sophisticated treatment strategies evolve and the number of survivors of long-term childhood cancer grows, the long-term complications of treatment and the cancer itself are becoming ever more important. One of the most important but often neglected complications is osteoporosis and increased risk of fracture during and after cancer treatment. Acquisition of optimal peak bone mass and...
- Original Articles
- The control of invasive
Candida infection in very low birth weight infants by reduction in the use of 3rd generation cephalosporin - Yu Jin Chang, Il Rak Choi, Won Sub Shin, Jang Hoon Lee, Yun Kyung Kim, Moon Sung Park
- Clin Exp Pediatr. 2013;56(2):68-74. Published online February 25, 2013
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Purpose To evaluate the effectiveness of new management policies on the incidence of invasive Candida infections
Methods This observational study involved a retrospective analysis of the patients' medical records. In total, 99 very low birth weight infants, who were admitted to the neonatal intensive care unit at Ajou University Hospital from January 2010 to December 2011, were enrolled for the study. Period I,...
- Predictors of nonresponse to intravenous immunoglobulin therapy in Kawasaki disease
- Hyo Min Park, Dong Won Lee, Myung Chul Hyun, Sang Bum Lee
- Clin Exp Pediatr. 2013;56(2):75-79. Published online February 25, 2013
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Purpose It has been reported that 10% to 20% of children with Kawasaki disease (KD) will not respond to intravenous immunoglobulin (IVIG) treatment. In this study, we aimed to identify useful predictors of therapeutic failure in children with KD.
Methods We examined 309 children diagnosed with KD at the Kyungpook National University Hospital and the Inje University Busan Paik Hospital between January 2005...
- Selenium and leptin levels in febrile seizure: a case-control study in children
- Abolfazl Khoshdel, Neda Parvin, Maedeh Abbasi
- Clin Exp Pediatr. 2013;56(2):80-85. Published online February 25, 2013
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Purpose Febrile seizures (FS) are seizures that occur between the age of 6 and 60 months, but its pathophysiology still is not fully understood. There is limited information about the correlation between levels of selenium and leptin with FS. This study aimed to determine the relationship between serum levels of selenium and leptin in children with FS.
Methods This case-control study was conducted...
- Case Reports
- Retropharyngeal abscess coinfected with
Staphylococcus aureus andMycobacterium tuberculosis after rhinoviral infection in a 1-month-old infant - Jeong Hee Shin, Se In Sung, Jin Kyu Kim, Ji Mi Jung, Eun Sun Kim, Soo Han Choi, Yae Jean Kim, Kang Mo Ahn, Yun Sil Chang, Won Soon Park
- Clin Exp Pediatr. 2013;56(2):86-89. Published online February 25, 2013
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A retropharyngeal abscess is a rare disease entity in young infants but can develop after nasopharyngeal viral infection. Group B
Streptococcus andStaphylococcus aureus are the most common pathogens in young infants, however,Mycobacterium tuberculosis is very rare. We report the case of retropharyngeal abscess and coinfection withS. aureus andM. tuberculosis in a very young infant presenting with...
- Transvenous proximal closure of large congenital coronary arteriovenous fistula using the single Amplatzer vascular plug in a 3-year-old girl
- Hae In Jang, Young Earl Choi, Hwa Jin Cho, Young Kuk Cho, Jae Sook Ma
- Clin Exp Pediatr. 2013;56(2):90-93. Published online February 25, 2013
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Congenital coronary arteriovenous fistulas (CCAFs) are rare coronary artery abnormalities in which blood is shunted into a cardiac chamber or great vessel. If the fistula itself is large and tortuous, it is generally recommended to occlude the fistula to prevent several complications. In approaches of transcatheter occlusion, the transvenous approach is preferred over the transarterial approach. The transvenous approach would...