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Volume 39(5); May 1996
Medical Lecture Courses
Clinical Applications of Near Infrared Spectroscopy
Won Soon Park
J Korean Pediatr Soc. 1996;39(5):595-602.   Published online May 15, 1996
Molecular Biology in Prenatal Diagnosis for Inborn Error of Metabolism
Kyuchul Choeh
J Korean Pediatr Soc. 1996;39(5):603-611.   Published online May 15, 1996
Clinical Lecture
Developmental Assessment in Pediatric Practice
Young-Jong Woo
J Korean Pediatr Soc. 1996;39(5):612-624.   Published online May 15, 1996
Original Articles
Comparison of Measles Specific IgG in the Sera of Infants and Children after Vaccination of Measles
Young Kyoo Shin, Hyung Suk Kim, Ji Tai Choung, Young Chang Tockgo
J Korean Pediatr Soc. 1996;39(5):625-630.   Published online May 15, 1996
Purpose : After recent epidemics of measles in Korea, Korean Pediatric Society recommended 2 dose measles vaccination schedule instead of 1 dose since 1991. However, the studies that supported the modification of vaccination schedule were insufficient yet. This study was performed to evaluate the vaccination efficacy of 1 dose and 2 dose vaccination. Methods : One dose vaccination group consisted of 19 infants(mean:...
Effect of Recombinant Human Erythropoietin on the Anemia of Premature Infants
Young Ah Lee, Ki Soo Kim, Young Seo Park, Hyung Nam Moon, Chang Yee Hong
J Korean Pediatr Soc. 1996;39(5):631-640.   Published online May 15, 1996
Purpose : To determine whether the prophylactic treatment with recombinant human erythropoietin(rHuEPO) for the anemia of prematurity would reduce the need for blood transfusions. Methods : We randomly assigned 17 premature infants to therHuEPO group and the control group. For the rHuEPO group (n=9, birth weight=1210¡¾156 g, gestational age=31.7¡¾1.9wk), rHuEPO (400U/kg) was given three times a week for 4 weeks, plus iron (8 mg/kg/day) and vitamin...
Growth and Neurodevelopmental Outcome on Very Low Birth Weight Infants During 2 Years
Eun Suk Kim, Jong Uk Kim, Oh Kyung Lee, Wan Soeb Kim
J Korean Pediatr Soc. 1996;39(5):641-651.   Published online May 15, 1996
Purpose : By rapid development of neonatal intensive care from 1960, we are able to expect the long survival of the very low birth weight infants. But, there were high risk of poor growth, neurodevelopmental delay, deafness, and blindness in very low birth weight infants. So, it is important to follow-up after discharge. We try to compare normal term infants with...
Clinical Significance of Simple Ventricular Septal Defect
Chang Ro Park, Myung Chul Hyun, Sang Bum Lee
J Korean Pediatr Soc. 1996;39(5):652-657.   Published online May 15, 1996
Purpose : To investigate the clinical significance and frequency of simple VSD by location of the defect and hemodynamic severity. Methods : We studied 482 cases who were diagnosed as simple VSD at department of Pediatrics, Kyung Pook University Hospital between December 1983 and July 1993. All cases were diagnosed by 2 dimensional echocardiography and cardiac catheterization was done in 256 cases. Results :...
Prognosis of Congenital Extrahepatic Biliary Atresia After Hepatic Portoenterostomy
Myung Hyun Sohn, Ki Sup Chung, Euh Ho Whang
J Korean Pediatr Soc. 1996;39(5):658-664.   Published online May 15, 1996
Purpose : The surgical results for congenital extrahepatic biliary atresia have been improved since Kasai first described hepatic portoenterostomy(Kasai operation) in 1959. This study was conducted to evaluate the postoperative prognosis of congenital extrahepatic biliary atresia after hepatic portoenterostomy. Methods : This clinical study was done by reviewing the medical records of 30 patients who have undergone hepatic portoenterostomy at the Severance Hospital, Yonsei...
β2-Microglobulin is a Sensitive Marker for Predicting Renal injury in Childhood Urinary Tract Infection
Won Uk Lee, Byung Moon An, IL Soo Kim, Eun Ryoung Kim
J Korean Pediatr Soc. 1996;39(5):665-672.   Published online May 15, 1996
Purpose : Urinary tract infection(UTI) in children may be cause of end stage renal failure and hypertension. So, early detection of renal scar, vesicoureteral reflux(VUR) and anomaly, and proper management are important. We carried this study to observe the significance of 24 hours urine β2-microglobulin(β2-MG) for predicting renal injury and correlation of β2-MG with the grade of VUR. Methods : We...
Studieson NormalValuesforRed Blood Cells in Korean Children
Soon Ki Kim, Byong Kwan Son
J Korean Pediatr Soc. 1996;39(5):673-681.   Published online May 15, 1996
Purpose : Values for hemoglobin, erythrocyte indices and red cell distribution width used in the diagnosis of anemia and iron deficiency are known to vary to some degree according to age. We tried to define age-related changes in red blood cells (RBC) profiles. Methods : With the eletronic counters routinely used in clinical laboratories we evaluated the RBC profiles of 1,717 samples of blood from...
Clinical Study of Hickman Catheters in Pediatric Oncologic Patient
Young-Ho Lee
J Korean Pediatr Soc. 1996;39(5):682-690.   Published online May 15, 1996
Purpose : We performed a retrospective study to evaluate the complications from Hickman catheters in pediatric oncologic patients. Methods : Between October 1992 and July 1995, 27 Hickman catheters placed in 25 patients who were chemotherapy candidates were evaluated. The frequency and etiologic organisms of catheter infections, mechanical complications, and any problems that might have been related to catheter use were determined. Results : 1) The...
Immunologic Abnormalitiesin Kawasaki Diseaseand the Effect ofIntravenousImmunoglobulin
Joon Sung Lee, Bin Cho, Sung Hoon Cho
J Korean Pediatr Soc. 1996;39(5):691-702.   Published online May 15, 1996
Purpose : It has been suggested that immunologic abnormalities play a role in the pathogenesis of vascular injury in Kawasaki disease and the immunologic abnormalities could be regulated by high-dose intravenous immunoglobulin(IVIG). We investigated the peripheral blood lymphocyte subsets, the serum levels of interleukin-6(IL-6) and tumor necrosis factor-α(TNF-α) and the effect of high-dose IVIG(400 mg/kg/day for 5 days) on these factors during acute stage of...
The Optimal Dosages of Gammaglobulin and Aspirin in Treating Kawasaki Disease
Seung Baik Han, Jong Woon Choi, Soon Ki Kim, Sei Woo Chung, Jeung Gyu Kim, Byong Kwan Son
J Korean Pediatr Soc. 1996;39(5):703-711.   Published online May 15, 1996
Purpose : There are some disagreements about the optimal dosages of intravenous gammaglobulin(IVGG) and oral aspirin(ASA) in the treatment of Kawasaki disease. So authors performed a prospective clinical study to evaluate the efficacy of IVGG 1g/kg plus ASA 50mg/kg/day. Methods : We treated 29 patients who were admitted to Inha University Hospital from June 1993 through May 1994 with IVGG 1g/kg plus ASA 50mg/kg/d. We...
Immunologic Changes of Peripheral Blood Lymphocytes in Kawasaki Disease after Intravenous Gamma Globulin Therapy
Jung Yeon Shim, Kyung Mo Kim, Young Hwue Kim, Soo-Jong Hong
J Korean Pediatr Soc. 1996;39(5):712-721.   Published online May 15, 1996
Purpose : Kawasaki disease(KD) is multi-systemic vasculitis and coronary artery abnormalities can develop up to 30 percent in untreated patients. Several observations suggest that immune activation and the secretion of cytokines from immune effector cells contribute to the pathogenesis of this disease. Though high dose intravenous gamma globulin(IVGG,>1 gm/kg) is effective in reducing the prevalence of coronary artery aneurysms in KD,...
Case Reports
Antiphospholipid Syndrome Presented with Pulmonary Embolism and Deep Venous Thrombosis in Child
Ran Lee, Il Soo Ha, Hae Il Cheong, Yong Choi
J Korean Pediatr Soc. 1996;39(5):722-726.   Published online May 15, 1996
Antiphospholipid syndrome is a thrombotic disorder and the serologic marker of the syndrome is antiphospholipid antibody(lupus anticoagulant, anticardiolpin antibody, or both). In a 13-year-old girl who presented with dyspnea, pulmonary embolism and femoral vein thrombosis were demonstrated by lung scan and abdominal ultrasonography. She had 3 out of 11 criteria for the diagnosis of SLE, such as thrombocytopenia, positive antinuclear antibody, low C3...
An Autopsy Case of Double Aortic Arch
Ji Sook Kim, Yong Myung Jo, Kyung Hee Ko, Eun Ryoung Kim, Je Grun Chi
J Korean Pediatr Soc. 1996;39(5):727-731.   Published online May 15, 1996
Double aortic arch is the most common type of symptomatic vascularring. In most patients, the symptoms are manifested at birth or in early infancy. Double aortic arch usually has more severe symptoms than other types of complete vascular rings. We experienced one case of complete duplicated double aortic arch with left descending aorta and left patent ductus arteriosus. A one-day-old female neonate was transferred...
A Case of Chronic Recurrent Multifocal Osteomyelitis
Weon Young Lee, Eell Ryoo, Mi Jin Jeong, Kye Hwan Seol, Kil Hyen Kim, Hak Su Lee
J Korean Pediatr Soc. 1996;39(5):732-737.   Published online May 15, 1996
Chronic recurrent multifocal osteomyelitis(CRMO) is an unusual inflammatory process involving multiple osseous sites. No causative agent can be consistently isolated from these lesions despite multiple biopsies and the affected child purses a clinical course of chronic remissions and exacerbations independent of antibiotic therapy. Biopsy of the lesions did not reveal any pathogens. Immunologic investigation revealed no abnormality common to the patient...
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