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Case Report
Long-term recombinant interferon-γ treatment in 2 cases of osteopetrosis
Dong-Yun Kim, Dong-Kyun Han, Hee-Jo Baek, Sung-Taek Jung, Hoon Kook, Tai-Ju Hwang
Clin Exp Pediatr. 2007;50(11):1129-1133.   Published online November 15, 2007
Osteopetrosis, a rare osteosclerotic bone disease characterized by a defect in osteoclast function and the reduced generation of superoxide by leukocytes, can be classified into several types based on their mode of inheritance, age of onset, severity, and associated clinical symptoms. Stem cell transplantation is the only curative therapy for the infantile malignant type, although alternative treatments, such as corticosteroids,...
Original Article
Second allogeneic hematopoietic stem cell transplantation in children to overcome graft failure or relapse after initial transplant
Dong-Yeon Kim, Do Kyun Kim, Soo Young Kim, Seok Joo Kim, Dong Gyun Han, Hee Jo Baek, Hoon Kook, Tai-Ju Hwang
Clin Exp Pediatr. 2006;49(12):1329-1339.   Published online December 15, 2006
Purpose : Failure of hematopoietic stem cell transplantation(HSCT) may be encountered in practice because of either relapse of the malignancy or dysfunction of the graft. Second HSCT may be the only option for some patients whose initial HSCT failed. Methods : From May, 1991 to December, 2004, 115 HSCTs were performed at the Pediatric Blood & Marrow Transplantation Center, Chonnam National...
Frequency of Platelet Transfusions and Outcome in Neonates with Thrombocytopenia
Suk-Hwan Lim, Jin-Hwa Kook, Chang-Yee Cho, Young-Youn Choi, Tai-Ju Hwang
Clin Exp Pediatr. 2002;45(8):961-966.   Published online August 15, 2002
Purpose : We compared the underlying or associated diseases according to the frequency of platelet transfusions in neonates with thrombocytopenia to know the factors predicting which patients will require multiple platelet transfusions. We also compared mortality. Methods : A retrospective study was performed in 72 neonates who received the platelet transfusions in neonatal intensive care unit(NICU) between August 1996 and July...
Characterization of Bruton's Tyrosine Kinase Genetic Mutations in One Korean X-linked Agammaglobulinemia Family
Eun-Kyeong Jo, Chang-Hwa Song, Jeong-Kyu Park, Young-Jong Baek, Hye-Young Rhu, Jae-Ho Lee, Tai-Ju Hwang, Hoon Kook
Clin Exp Pediatr. 2002;45(2):183-191.   Published online February 15, 2002
Purpose : X-linked agammaglobulinemia(XLA) is an immunodeficiency caused by abnormalities in Bruton's tyrosine kinase(Btk), and is characterized by a deficiency of peripheral blood B cells. We studied the cytoplasmic expression of Btk protein and analyzed the Btk gene in peripheral blood mononuclear cells from two siblings and one cousin with XLA, as well as additional family members. Methods : Btk...
Clinical Trends in Acute Rheumatic Fever in Korean Children : Mailed Questionnaire Survey from 1988 to 1997 (Compared with 1978-1987)
Hyeon-Ho Kang, Sung-Ho Cha, Kyong-Su Lee, Sang-Bum Lee, Tae-Chan Kwon, Young-Chang Tockgo, Chang-Sung Son, Jin-A Son, Hee-Ju Park, Yong-Soo Yun, Jung-Yun Choi, Chang-Hwi Kim, Chul-Ho Kim, Tai-Ju Hwang, Jae-Sook Ma, Chan-Uhng Joo, Nam-Su Kim
Clin Exp Pediatr. 1999;42(10):1381-1391.   Published online October 15, 1999
Purpose : The purpose of this study was to assess the frequency of acute rheumatic fever(ARF) among children in Korea and to describe trends in its clinical characteristics compared to data from a previous study(1978-1987). Methods : A mailed questionnaire survey sent to the pediatric departments of 13 general hospitals in Korea requested the total number of patients with ARF and...
Acinetobacter Infection in Neonatal Intensive Care Units(NICU)
Won-Gyu Bum, In-Suk Kim, Young-Hee Kim, Young-Youn Choi, Jae-Sook Ma, Tai-Ju Hwang
Clin Exp Pediatr. 1994;37(12):1669-1675.   Published online December 15, 1994
Purpose : Acinetobacter becomes one of the important organisms in hospital infection especially intensive care units. Recently we experienced four times of outbreaks of Acinetobacter infection in Neonatal Intensive Care Units(NICU), Chonnam University Hospital. Clinical and epidemiologic study was performed to emphasize the importance of hospital infection. Methods : During the period from November 1992 to July 1993, twenty-one patiencts of...
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