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Original Article
The Safety and Immunogenicity of a Trivalent, Live, Attenuated MMR Vaccine, PriorixTM
Seung-In Ahn, Min-Kook Chung, Jung-Suk Yoo, Hye-Jeon Chung, Jae-Kyun Hur, Young-Kyu Shin, Jin-Keun Chang, Sung-Ho Cha
Clin Exp Pediatr. 2005;48(9):960-968.   Published online September 15, 2005
Purpose : This multi-center, open-label, clinical study was designed to evaluate the safety and immunogenicity of a trivalent, live, attenuated measles-mumps-rubella(MMR) vaccine, PriorixTM in Korean children. Methods : From July 2002 to February 2003, a total of 252 children, aged 12-15 months or 4-6 years, received PriorixTM at four centers : Han-il General Hospital, Kyunghee University Hospital, St. Paul's Hospital at...
Case Report
Two Cases of Rotor Syndrome in Siblings
Hwa-Jin Park, Eun-Sung Kim, Ji-Young Chung, Sung-Ho Cha, Deog-Yoon Kim
Clin Exp Pediatr. 2004;47(8):892-895.   Published online August 15, 2004
Rotor syndrome is a rare benign familial disorder characterized by chronic, fluctuating, nonhemolytic and predominantly direct bilirubinemia with normal liver tissue. We have recently experienced two cases of Rotor syndrome in a brother and sister. They revealed icteric sclerae with mild hepatomegaly in physical examination. Laboratory findings showed increased serum bilirubin with direct bilirubin predominance. The urinary excretion of total...
Original Article
Serological Analysis and Epidemiologic Characteristics of Group A Streptococci in Seoul(1998-2000)
Sun-Hee Choi, Yun-Ho Kim, Sung-Ho Cha, Ki-Sang Kim, Young-Hee Lee
Clin Exp Pediatr. 2002;45(11):1368-1372.   Published online November 15, 2002
Purpose : Group A streptococci have a cell wall which consists of M protein and T protein. T protein is known to be helpful in the understanding of the epidemiology of group A streptococci. To study the epidemiologic characteristics, we serotyped T protein of group A streptococci obtained from patients admitted to hospitals, or who visited OPD in five districts...
Molecular Epidemiologic Study of Streptococcus pyogenes Analyzed by T protein Serotyping and Pulsed Field Gel Electrophoresis(PFGE) in Normal Children
Jin Ah Son, Don Hee Ahn, Kyu Jam Hwang, Younghee Lee, Sung-Ho Cha
Clin Exp Pediatr. 2000;43(10):1330-1342.   Published online October 15, 2000
Purpose : In this study we tried to look at the spreading, duration of colonization, and acquisition of new streptococci which were obtained in one geographical area, as well as the bacteriologic and molecular epidemiology of normal school children carrying group A streptococci and their clonal relationship through the combined application of the serotype of T antigen and Pulsed Field...
Epidemiologic Characteristics of T Serotyping in Relation to the Outbreak of Erythromycin Resistant Streptococcus pyogenes
Sung-Ho Cha, Kyu Jam Hwang, Young Hee Lee
Clin Exp Pediatr. 2000;43(10):1323-1329.   Published online October 15, 2000
Purpose : The identification of antigenic specificity of Streptococcus pyogenes using T serotyping is important to understand biologic characteristics of microorganisms. We would like to disover the association of the occurrence of predominant T type, with possible outbreak of erythromycin resistant Streptococcus pyogenes in this country, which has been documented since the late 1990s. Methods : Throat swab cultures were taken...
Clinicial Observations of Oliguric Acute Renal Failure in Children
Sung-Soo Lee, Young-Mi Choi, Chong-Woo Bae, Sung-Ho Cha, Byoung-Soo Cho
Clin Exp Pediatr. 1999;42(10):1419-1425.   Published online October 15, 1999
Purposes : We studied the clinicial findings of oliguric acute renal failure(ARF) developed on admission or during treatment of other diseases. Methods : We performed a retrospective analysis of medical records of 118 patients with oliguric ARF who had been admitted to Kyunghee University Hospital since January 1988 to December 1997. Diagnostic criteria of oliguric ARF are serum creatinine>1.0mg/dl and urine...
Clinical Trends in Acute Rheumatic Fever in Korean Children : Mailed Questionnaire Survey from 1988 to 1997 (Compared with 1978-1987)
Hyeon-Ho Kang, Sung-Ho Cha, Kyong-Su Lee, Sang-Bum Lee, Tae-Chan Kwon, Young-Chang Tockgo, Chang-Sung Son, Jin-A Son, Hee-Ju Park, Yong-Soo Yun, Jung-Yun Choi, Chang-Hwi Kim, Chul-Ho Kim, Tai-Ju Hwang, Jae-Sook Ma, Chan-Uhng Joo, Nam-Su Kim
Clin Exp Pediatr. 1999;42(10):1381-1391.   Published online October 15, 1999
Purpose : The purpose of this study was to assess the frequency of acute rheumatic fever(ARF) among children in Korea and to describe trends in its clinical characteristics compared to data from a previous study(1978-1987). Methods : A mailed questionnaire survey sent to the pediatric departments of 13 general hospitals in Korea requested the total number of patients with ARF and...
Clinical Application of a Scoring System in the Diagnosis of Group A Streptococcal Pharyngitis
Hyeon-Bu Kim, Byung-Soo Cho, Sung-Ho Cha, Jeong-Hun Ha, Sun-Hee Kim, Gui-Sook Cho
Clin Exp Pediatr. 1998;41(10):1365-1371.   Published online October 15, 1998
Purpose : A scoring system could be clinically useful in determining cases in which a throat culture may be omitted or in cases whether antibiotics may be initiated or not. We propose to make a clinical guideline of antibiotics administration in patients with pharyngitis. Methods : From Apr. 1996. to Mar. 1997, throat cultures were taken from 321 cases(72 cases from...
Nationwide Survey on Group A beta-Hemolytic Streptococcal Carrier Rate in Normal Korea School Children in 1996
Sung-Ho Cha, Yong-Mook Choi, Sei-Won Yang, Dong-Hwan Lee, Chong-Guk Lee, Chang-Ho Hong
Clin Exp Pediatr. 1998;41(5):585-592.   Published online May 15, 1998
Purpose : The accuracy of bacteriologic diagnosis of beta-hemolytic streptococcal pharyngotonsillitis depends on the degree of carrier rate in that area. It is the purpose of this study to obtain the carrier rate from seven different areas and to find results and epidemiologic factors. Methods : Throat swab was obtained from the tonsillar fossa of normal school children during March through...
The Correlation between a Semi-quantitative ASO(Antistreptolysin O) Assay by Rantz-Randall and a Quantitative ASO Assay by Nephelometry
Sung-Keun Park, Seok-Hee Ahn, Jung-Woo Lee, Byoung-Soo Cho, Sung-Ho Cha, Yong-Mook Choi
Clin Exp Pediatr. 1997;40(12):1670-1674.   Published online December 15, 1997
Purpose : Accurate diagnosis and prompt treatment of infection with Streptococcus pyogenes (group A streptococci) is required as it may cause many complications, and chronic serious sequelae, acute rheumatic fever and acute glomerulonephritis. Recently, the assay methods of ASO concentration tend to be changed into quantitatively from semi-quantitative or qualitative methods in this country. We would like to know relationships and degree of concurrences between...
Appraisal of the Results of Throat Swab Culture Obtained from Pediatric Outpatient Clinic
Sung-Ho Cha, Byoung-Soo Cho, Hwan-Jo Suh, Jin-Tae Suh, Seon-Ju Kim
Clin Exp Pediatr. 1995;38(7):895-900.   Published online July 15, 1995
Purpose : We can meet a lot of patients with the upper respiratory tract infection in outpatient clinic, most of them are caused by viral in origin, which make us consider prudent prescribing antibiotics. But on the other hand, the accurate diagnosis and proper treatment of group A streptococcal upper respiratory infection should be emphasized concerning about possible development of...
Clinical Review of Positive Antinuclear Antibody(ANA) Test in Pediatric Patients
Dong-Jin Choi, Kye-Sik Shim, Hyok Choi, Byoung-Soo Cho, Sung-Ho Cha, Jin-Tae Suh
Clin Exp Pediatr. 1994;37(10):1397-1404.   Published online October 15, 1994
The antinuclear antbody (ANA) test have been used to screen the patients with systemic lupus erythematosus (SLE) and other autoimmune diseases. We had retrospectively reviewed the 263 records of pediatric patients with doing ANA tests who admitted at Department of Pediatrics, Kyung Hee University Hospital, from January 1988 to May 1993. The following results were obtained. 1) The positive rate of ANA...
Case Report
Pulmonary Artery Sling with Situs Solitus Dextroposition of Heart and Left Superior Vena Cava
Sung-Ho Cha, Sung- Yong Jung, Pill-Jin Shin, Byong-Soo Cho, Chang-Il Ahn, Sun-Wha Lee
Clin Exp Pediatr. 1994;37(2):257-261.   Published online February 15, 1994
Pulmonary artery sling is a rare congenital cardiovascular anomaly which presents clinical obstructive symptoms and signs of trachea, right main bronchus and esophagus due to left pulmonary artery abnormaly arises from proximal part of right pulmonary artery. Aberrant left pulmonary artery courses to the right above right main bronchus and then turns to the left, and courses to between the...
Original Article
The Clinical Observation in Kawasaki Disease
Min-Young Park, Gye-Sik Shim, Sung-Ho Cha, Chang-Il Ahn
Clin Exp Pediatr. 1994;37(2):167-174.   Published online February 15, 1994
One-hundred ninty five cases with Kawasaki disease who diagnosed and treated at the Department of Pediatrics, Kyung Hee University Hospital from January 1985 to June 1993, were investigated for their clinical manifestations and laboratory findings, and cardiac complications. The results are as follows: 1) Most patients (92.8%) were under 5 years of the age. 2) Boys were more prevalent than girls, as a...
Case Report
Three Cases of Atypical Kawasaki Disease with Coronary Aneurysm
Min-Young Park, Kwang-Sun Han, Sung-Yoon Cho, Byoung-Soo Cho, Sung-Ho Cha
Clin Exp Pediatr. 1993;36(9):1315-1319.   Published online September 15, 1993
Kawasaki disease is described by fever lasting five days or more, bilateral conjunctival injection, changes of lips and oral cavity, polymorphous exanthema, acute non-purulent cervical lymphadenopathy, and changes of extremities. Atypical Kawasaki disease is defined as fewer than 4 of 6 criteria described above including coronary artery abnormalities. Especially, atypical clinical manifestations of Kawasaki disease appear in infants younger than 6...
A Case of Infectious Mononucleosis Associated with Facial Nerve Palsy
Ho-Suk Lee, Jin-Park , Il-Soo Kim, Sung-Ho Cha, Byoung-Soo Cho, Chang-Il Ahn
Clin Exp Pediatr. 1993;36(4):579-582.   Published online April 15, 1993
Infectious Mononucleosis is a common sysemic illness primarily invloving children and young adults and due apparently to the Epstein-Barr virus (EBV). Although the typical case is easily recogniged, unusual manifestations or serious complications occur frequently enough to pose problems in diagnosis and management. Neurologic complications are rare(1%). These nerologic complications may actually precede the full clinical picture or presen: as the sole...
Acute Tubular Necrosis Associated with Typhoid Fever
Sung-Yoon Cho, Kyu-Young Lee, Sung-Ho Cha, Byoung-Soo Cho, Chang-Il Ahn, So-Yeon Yu, Mun-Ho Yang, Soon-Don Hong
Clin Exp Pediatr. 1992;35(6):867-872.   Published online June 15, 1992
Acute tubular necrosis has been rarely reported in typhoid fever. We experienced a case of acute tubular necrosis due to typhoid fever in a 5 years old male patient. The patient showed significant titer of widal reaction associated with acute renal failure. Renal boipsy finding was compatible with acute tubular necrosis and immune complex was not deposited. Clinical and urinary...
Medical Lecture Course
Reappriasal of the Group A Beta Streptococcal Upper Respiratory Infection and Its Carrier -Relationship with Acute Rheumatuc Fever-
Sung-Ho Cha
Clin Exp Pediatr. 1992;35(6):733-743.   Published online June 15, 1992
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