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Original Article
The effect of rhinovirus on airway inflammation in a murine asthma model
Eugene Kim, Huisu Lee, Hyun Sook Kim, Sulmui Won, Eu Kyoung Lee, Hwan Soo Kim, Kyongwon Bang, Yoon Hong Chun, Jong-Seo Yoon, Hyun Hee Kim, Jin Tack Kim, Joon Sung Lee
Clin Exp Pediatr. 2013;56(11):482-489.   Published online November 27, 2013
Purpose

The aim of the present study was to investigate the differences in lower airway inflammatory immune responses, including cellular responses and responses in terms of inflammatory mediators in bronchoalveolar lavage fluid (BALF) and the airway, to rhinovirus (RV) infection on asthma exacerbation by comparing a control and a murine asthma model, with or without RV infection.

Methods

BALB/c mice were intraperitoneally injected...

Effect of respiratory syncytial virus infection on regulated on activation, normal T-cells expressed and secreted production in a murine model of asthma
Yanghua Ju, Seung Jun Choi, Huisu Lee, Hyun Sook Kim, Sulmui Won, Yoon Hong Chun, Jong-Seo Yoon, Hyun Hee Kim, Joon Sung Lee
Clin Exp Pediatr. 2011;54(11):456-462.   Published online November 30, 2011
Purpose

Synthesis of regulated on activation, normal T-cells expressed and secreted (RANTES) in the airway has previously been shown to be elevated after respiratory syncytial virus (RSV) infection. However, since few studies have examined whether RSV-infected asthma patients express a higher level of RANTES than do normal individuals, we used a murine model of asthma to address this question.

Methods

We prepared Dermatophagoides...

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