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Original Article
Analysis on the cause of eosinophilia in a neonatal intensive care unit
Jeoung Young Kim, Hyo Bin Im, Min Jung Sung, Sang Hee Son, Son Sang Seo
Clin Exp Pediatr. 2010;53(1):28-32.   Published online January 15, 2010
Purpose : Although eosinophilia is a common laboratory finding in many neonatal intensive care units (ICUs), its causative mechanisms remain obscure. We aimed to determine the causes of eosinophilia in the neonatal ICU environment. Methods : Serial eosinophil counts were determined weekly for 288 hospitalized, appropriately grown neonates. Infants were divided into four groups according to gestational age, and the...
Case Report
Isolated 3-Methylcrotonyl CoA Carboxylase Deficiency Detected by Newborn Screening Program Using Tandem Mass Spectrometry
Ju Young Kwak, Jun Young Park, Kyung A Nam, Sang Hi Son, Son Sang Seo
Clin Exp Pediatr. 2005;48(5):561-564.   Published online May 15, 2005
Isolated deficiency of 3-methylcrotonyl CoA carboxylase is a rare disorder of the catabolic pathway for leucine and many patients have mild symptoms or no symptom. However, the introduction of tandem mass spectrometry in newborn screening has revealed an unexpectedly high incidence of this disorder. We report an asymptomatic premature infant with isolated 3-methylcrotonyl CoA carboxylase deficiency detected by newborn screening...
Original Article
The Efficacy of Nebulized 3 Percent Hypertonic Saline Solution and Fenoterol in Infants with Bronchiolitis
Joon Young Park, Young Mi Jeong, Soo Jin Jeong, Son Sang Seo
Clin Exp Pediatr. 2005;48(5):518-522.   Published online May 15, 2005
Purpose : To evaluate the effect of inhaled hypertonic saline solution in hospitalized infants with bronchiolitis. Methods : A randomized double blind trial was performed from October 2003 to May 2004. A total of eighty patients <1 year of age with a clinical diagnosis of acute viral bronchiolitis were enrolled and assigned to receive either of the following : inhalation of...
The Efficacy of Nebulized Epinephrine Versus Fenoterol in Hospitalized Infants with Acute Bronchiolitis
Sang Hee Lee, Kyung Ah Nam, Ji Youn Choi, Meen Jung Kim, Son Sang Seo
Clin Exp Pediatr. 2004;47(9):953-958.   Published online September 15, 2004
Purpose : Acute bronchiolitis is a lower respiratory tract disease, resulting from inflammatory obstruction of the small airway. The main treatment of acute bronchiolitis is supportive but, numerous investigators have examined the efficacy of beta agonist as bronchodilators. In acute bronchiolitis, mucosal edema in the bronchioles may be an important cause of airway obstruction therefore, an alpha and beta agonist...
The Diagnostic Value of Gross Bloody Stool on Intussusception
Kyung Ah Nam, Sang Hee Lee, Sang Hee Son, Su Jin Jung, Son Sang Seo
Clin Exp Pediatr. 2004;47(8):851-854.   Published online August 15, 2004
Purpose : To evaluate the diagnostic value of gross bloody stools as a predictor of intussusception. Methods : We reviewed 159 cases retrospectively that had an ultrasound examination for diagnosis of intussusception from January 2001 to December 2003 at Ilsin Christian Hospital. We compared each symptom and assessed the diagnostic value of gross bloody stools in the patients with suspected intussusception. Results...
Case Report
A Case of Maple Syrup Urine Disease Associated with Acrodermatitis Enteropathica-like Syndrome Due to Iisoleucine Deficinecy During Diet Therapy
Ki Hyang Moon, Oh Sook Gwon, Jung Im Lee, Seong Woo Rho, Seong Sook Jeon, Son Sang Seo
Clin Exp Pediatr. 2001;44(4):469-474.   Published online April 15, 2001
Maple syrup urine disease(MSUD) is an autosomal recessive disorder involving the metabolism of the branched-chain amino acids(BCAA) such as leucine, isoleucine and valine. The disorder is due to a defect in branched-chain α-ketoacid dehydrogenase(BCKAD) and the classic form causes rapid progressive and overwhelming illness beginning in the first weeks of life, present with poor feeding, lethargy, change in muscle tone,...
Original Article
Comparison of Preventive Effect of RDS and Neonatal Morbidity between Antenatal Dexamethasone versus Ambroxol Administration
Eun Jeong, Kim, Seong Sook Jeon, Son Sang Seo
Clin Exp Pediatr. 2000;43(1):13-22.   Published online January 15, 2000
Purpose : Antenatal dexamethasone administration is associated with a significant lowering respiratory distress syndrome(RDS) incidence, but can increase neonatal infection. Ambroxol has been accepted as an alternative treatment to dexamethasone and is of at least equal efficacy but without adverse reaction. The aim of this study was to evaluate the effectiveness of ambroxol versus dexamethasone in RDS incidence and neonatal...
Gastric Emptying Time in Preterm Infents : Comparison between Breast Milk and Formula Milk
Seong Woo Roh, Seong Sook Jeon, Son Sang Seo, Jeong Mi Kwon
Clin Exp Pediatr. 1999;42(3):324-331.   Published online March 15, 1999
Purpose : Failure of adequate gastric emptying frequently interferes with successful enteral nutrition in infants. Study of gastric emptying in preterm infants has been hampered by the absence of a suitable and, valid technique, but ultrasonic assessment is well tolerated by infants. The aim of this study is to compare gastric emptying rates of breast milk and formula within preterm...
Bone Mineral Metabolism and Rickets Compared between Fortified Human Milk and Preterm Formula Feeding in Prematurity
Hong Sun Ju, Eun Young Jeong, Seong Sook Jeon, Son Sang Seo
Clin Exp Pediatr. 1998;41(11):1476-1483.   Published online November 15, 1998
Purpose : To compare the effect of breast milk containing fortifier with preterm formula on bone mineral metabolism in premature infants, we evaluated the state of bone mineralization, biochemical alteration and the frequency of rickets during the first five months of life. Methods : Fourteen fortified breast milk-fed infants and eleven preterm formula-fed infants who were born at Il-Sin...
Nitroglycerin Treatment in Persistent Pulmonary Hypertension of the Newborn
Ji Sook Kim, Sung Sook Jeon, Son Sang Seo
Clin Exp Pediatr. 1997;40(11):1529-1536.   Published online November 15, 1997
Purpose : Persistent pulmonary hypertension(PPHN) of the newborn has been treated with some vasodilators including tolazoline. But these drugs have many side effects, especially systemic hypotension . To investigate the usefulness of the nitroglycerin as a specific vasodilator with few side effects, this study was done. Methods : Nitroglycerin was administered within 1st one day after birth in 8 newborn infants who were diagnosed as...
Case Report
A Case of Neuronal Heterotopia
Jeong Hae Joo, Eun Joo Seok, Min Jeong Kim, Son Sang Seo
Clin Exp Pediatr. 1997;40(8):1173-1177.   Published online August 15, 1997
Neuronal migrational disorders of the brain represent abnormalities in the formation of the neocortex caused by faulty migration of the subependymal neuroblasts. The neuroblasts normally migrate between the sixth and 15th gestational week and in doing so form the six-layered neocortex. When the migration does not occur in a normal fashion the resultant brain anomalies include lissencephaly, pachygyria, schizencephaly, hemimegalencephaly, heterotopia, and polymicrogyria. Neuronal heterotopia is...
Original Article
Effect of Indomethacin Therapy in Prematurity with Patent Ductus Arteriosus:study of Its Effectiveness in Treatment Modality
Yun Kyeong Bae, Seong Woo Roh, Min Jeong Kim, Son Sang Seo
Clin Exp Pediatr. 1996;39(9):1239-1246.   Published online September 15, 1996
Purpose : Conventional indomethacin therapy(0.2mg/kg every 12 hours for three doses) has been used for closure of PDA. The effect of prolonged low dose of indomethacin therapy(0.1mg/kg daily for six days)had been reported in foreign country but, nothing had been reported in our country. So we attempted this study to examine effects of these two methods. Methods : Forty one infants with PDA of...
Case Report
Two Cases of Neonatal Adrenal Hemorrhage
Kyeong Hye Jeong, Sung Suk Jeon, Ok Sung Jeong, Son Sang Seo, Jung Mee Kweon
Clin Exp Pediatr. 1995;38(10):1411-1416.   Published online October 15, 1995
Neonatal adrenal hemorrhage is not uncommon due to its relative large size and vascularity, thus making it vulnerable to traumatic and asphyxial injuries. It뭩 etiology is unknown, but postulated etiologies include maternal diabetes, obstetric trauma, asphyxia, thrombocytopenia and coagulation defect. Clinical manifestations ate those of a paplable mass in the affected flank, anemia and jaundice. Hypoglycemia, hypotension and hypovolemia may...
Original Article
A Clinical Observation of 23 Cases of Necrotizing Enterocolitis
Ok Young Kim, Eun Ju Jeong, Min Jeong Kim, Mi Yeon Park, Son Sang Seo
Clin Exp Pediatr. 1995;38(7):886-894.   Published online July 15, 1995
Purpose : We observed risk factors, clinical findings, diagnosis and treatment of NEC in 23 cases in order to try to prevent developement of, and improve the prognosis of necrotizing enterocolitis(NEC) in the future. Methods : 23 cases of NEC who were admitted to the NICU of Ilsin Christian Hospital between Jan 1992 and June 1994 were studied. Data about birth...
Clinical Study on Twins
Sang Hee Lee, Ok Young Kim, Son Sang Seo
Clin Exp Pediatr. 1993;36(12):1663-1671.   Published online December 15, 1993
Clinical survey was performed on 413 cases of twin pregnancies and their 816 twin babies who were born at IlSin Christian Hospital during 5years from January 1987 to December 1991. The result of study was as follows : 1) There was 413 twin pregnancies among 40,711 deliveries, so the incidence of twins was 1 : 98.6. Average male-female sex ratio of twins...
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