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Case Report
Rheumatology
Recurrent macrophage activation syndrome since toddler age in an adolescent boy with HLA B27 positive juvenile ankylosing spondylitis
Joon Hyeong Park, Yu Mi Seo, Seung Beom Han, Ki Hwan Kim, Jung Woo Rhim, Nack Gyun Chung, Myung Shin Kim, Jin Han Kang, Dae Chul Jeong
Clin Exp Pediatr. 2016;59(10):421-424.   Published online October 17, 2016

Recurrent macrophage activation syndrome (MAS) is very rare. We present the case of an adolescent boy with human leukocyte antigen (HLA) B27-positive ankylosing spondylitis (AS), who experienced episodes of recurrent MAS since he was a toddler. A 16-year-old boy was admitted because of remittent fever with pancytopenia and splenomegaly after surgical intervention for an intractable perianal abscess. He had been...

Review Article
BK virus-associated hemorrhagic cystitis after pediatric stem cell transplantation
Seung Beom Han, Bin Cho, Jin Han Kang
Clin Exp Pediatr. 2014;57(12):514-519.   Published online December 31, 2014

Hemorrhagic cystitis is a common stem cell transplantation-related complication. The incidence of early-onset hemorrhagic cystitis, which is related to the pretransplant conditioning regimen, has decreased with the concomitant use of mesna and hyperhydration. However, late-onset hemorrhagic cystitis, which is usually caused by the BK virus, continues to develop. Although the BK virus is the most common pathogenic microorganism of poststem...

Case Report
Use of intravenous immunoglobulin in a disseminated varicella infection in an immunocompromised child
Jae Hong Kim, Dae Hyun Kwon, E Young Bae, Seung Beom Han, Jae Wook Lee, Nack Gyun Chung, Dae Chul Jeong, Bin Cho, Jin Han Kang, Hack Ki Kim
Clin Exp Pediatr. 2014;57(8):370-373.   Published online August 25, 2014

Varicella-zoster virus infection can lead to severe illness in immunocompromised patients. Further the mortality rate of disseminated varicella infection is extremely high particularly in immunocompromised children. We report a case of disseminated varicella infection in a child with acute lymphoblastic leukemia who was receiving chemotherapy, but was initially admitted with only for acute abdominal pain. The patient rapidly developed severe...

A case of Kikuchi-Fujimoto disease with autoimmune thyroiditis
Eun Ji Go, You Jin Jung, Seung Beom Han, Byung Kyu Suh, Jin Han Kang
Clin Exp Pediatr. 2012;55(11):445-448.   Published online November 23, 2012

Kikuchi-Fujimoto disease (KFD) is a benign self-limiting disease characterized by fever and lymphadenitis. The etiology and pathogenesis of KFD is unclear. However, two hypotheses have been suggested: a viral infection hypothesis and an autoimmune hypothesis. Several KFD patients with various types of autoimmune diseases have been reported, and these reports support the hypothesis for autoimmune pathogenesis of KFD. Here, we...

Original Article
Regional differences in phylogenetic group of Escherichia coli strains isolated from children with urinary tract infection in Korea
Ui-Yoon Choi, Seung Beom Han, Soo Young Lee, Jin Han Kang, Sun Mi Kim, Sang Hyuk Ma
Clin Exp Pediatr. 2012;55(11):420-423.   Published online November 23, 2012
Purpose

We phylogenetically analyzed the Escherichia coli strains isolated from children with urinary tract infection (UTI) in 2 regions of Korea. Virulence factors (VFs) and antibiotic resistance of the strains were also determined to compare the possible differences.

Methods

A total of 138 E. coli strains were collected from the 2 regions; Gyeongin (78 strains) and Gyeongnam (60 strains). The phylogenetic groups were...

Performance effectiveness of pediatric index of mortality 2 (PIM2) and pediatricrisk of mortality III (PRISM III) in pediatric patients with intensive care in single institution: Retrospective study
Hui Seung Hwang, Na Young Lee, Seung Beom Han, Ga Young Kwak, Soo Young Lee, Seung Yun Chung, Jin Han Kang, Dae Chul Jeong
Clin Exp Pediatr. 2008;51(11):1158-1164.   Published online November 15, 2008
Purpose : To investigate the discriminative ability of pediatric index of mortality 2 (PIM2) and pediatric risk of mortality III (PRISM III) in predicting mortality in children admitted into the intensive care unit (ICU). Methods : We retrospectively analyzed variables of PIM2 and PRISM III based on medical records with children cared for in a single hospital ICU from January 2003...
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