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Original Article
Assessment of Chromosomal Analyses of 1,180 Cases Suspected of Chromosomal Aberrations
Hyeon Kyoung Jeong, Eun Young Ahn, Sung Soo Rim, Eun Young Kim, Kyoung Sim Kim, Yong Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 2002;45(3):311-319.   Published online March 15, 2002
Purpose : We have performed this study to obtain reference data for the distribution of chromosomal aberrations in Korea. Methods : We analyzed 1,180 chromosomal study cases from Kwang ju Christian Hospital during the past 25 years. 756 cases suspected of characteristic chromosomal aberration syndromes and 424 cases with hermaphroditism, mild sexual abnormalities, multiple anomalies, or mental & growth retardation...
The Prognosis and Factors of Neonatal Thyroid Dysfunction
Yun Yee Kim, Kyoung Sim Kim, Yong Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 2000;43(1):23-33.   Published online January 15, 2000
Purpose : The function of the neonatal thyroid is affected transiently or consistently by various maternal thyroid diseases, neonatal diseases, drugs, and more as well as thyroid dysgenesis. In this study, we analyzed several factors of neonatal thyroid dysfunction through neonatal screening test and investigated the prognosis. Methods : From January 1992 to July 1997, we reviewed 66 newborn patients, who showed abnormal thyroid function...
Survey of Harada Scoring of Occurrence of Coronary Aneurysm in Kawasaki Disease Compared to Current Criteria
Chang Kyu Nam, Yong Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1999;42(7):928-935.   Published online July 15, 1999
Purpose : Gamma-globulin is effective in preventing coronary aneurysm, the primary complication of Kawasaki disease(KD). However, in order to predict high-risk cases which absolutely require γ-globulin, because of its high expenses, Harada score(HS) was introduced in Japan in 1990. We attempted to compare HS scoring with the health insurance criteria currently used in Korea. Methods : Retrospective studies were performed on...
Case Report
A Case of Hinman Syndrome Successfully Treated by Non-Surgical Measures
Won Seoung Lee, Chang Weon Oh, Ki Bok Kim
Clin Exp Pediatr. 1999;42(5):722-727.   Published online May 15, 1999
Hinman syndrome is a condition caused by an incoordination between the detrusor and external urethral sphincter during bladder contraction. Manifestations include day-and-night wetting, residual urine, infected urine, vesicoureteral reflux, christmas-tree shaped bladder-wall change, and upper tract damage without neurologic lesion or anatomical obstruction. Recently, this incoordination was postulated to be due to over-compensation of the external sphincter which compensates the...
A Case of Cavernous Sinus Thrombosis due to a Mistreated Facial Furuncle
Chae Yun Cho, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1999;42(4):584-588.   Published online April 15, 1999
Infections of the face, especially of the medial third or “the danger triangle”, are the most frequent primary foci associated with thrombosis of cavernous sinus. Microorganisms entering the facial vein and pterygoid plexus from these sites are easily carried to the sinus through the ophthalmic vein. When the septic thrombosis involves various structures in the sinus, multiple clinical manifestations develop...
Original Article
A Nationwide Clinical Study of Acute Respiratory Distress Syndrome in Children
Soo Jung Choi, Do Suck Jeong, Jae Won Oh, Ha Baik Lee, Im Ju Kang, Kwang Woo Kim, Kyu Earn Kim, Ki Bok Kim, Young Ho Rah, Kang Seo Park, Byong Kwan Son, Ki Young Lee, Sang Il Lee, Ji Tai Choung, Young Mi Hong
Clin Exp Pediatr. 1999;42(1):23-31.   Published online January 15, 1999
Purpose : Acute respiratory distress syndrome(ARDS) is the final course of acute lung injury. It results from various etiological origins and pathophysiologic mechanisms, and has a mortality rate of approximately 60-70%. Although the confirmative incidence of ARDS in children is yet unknown, the increasing incidence of ARDS has been reported in Korea. In the present study, we report ARDS diagnosed...
Case Report
Two Cases of Double-Orifice Mitral Valve Detected by Echocardiography
Kwan Cheol Oh, Yong Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1998;41(6):825-830.   Published online June 15, 1998
Double-orifice mitral valve is a rare congenital anomaly. Most cases of double-orifice mitral valve are hemodynamically normal and remain symptomless, so that it is usually discovered incidentally in autopsy or during surgical correction of a cardiovascular abnormality. Recently, however, it is increasingly recognized as such, since the echocardiography has gained wide acceptance as a non-invasive diagnostic tool by the M-mode, two-dimensional and color Doppler echocardiogram....
Original Article
Prognosis of Bacterial Meningitis based on Cerebrospinal Fluid Culture
Yun Ju Lee, Won Sung Lee, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1998;41(5):614-621.   Published online May 15, 1998
Purpose : The present study was undertaken to assess whether the results of cerebrospinal fluid (CSF) culture are related to prognosis. Methods : Subjected to this study were 51 cases admitted to our department who had been diagnosed as bacterial meningitis. They were divided into two groups, Group Ⅰ(20) with positive CSF culture and Group Ⅱ(31) with negative outcome, then both...
Case Report
A Case of Berry Syndrome associated with Syndactyly
Sang Chun Jung, Kyoung Sim Kim, Yong Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1998;41(4):543-547.   Published online April 15, 1998
Berry syndrome is a rare association of congenital heart anomalies which consists of a distal aortopulmonary window with aortic origin of the right pulmonary artery and hypoplasia or interruption of the aortic arch. This defect can be corrected only by immediate surgical intervention, so accurate preoperative diagnosis and detailed anatomic depiction of this syndrome are important in prognosis. We experienced a case of Berry...
Original Article
The Pelvic Changes of Patients with Down Syndrome in Korea
Jong Park, Kwan Cheol Oh, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1997;40(2):159-166.   Published online February 15, 1997
Purpose : Since Caffey et al. first described the anomaly in pelvis among the Down patients, decreased iliac and pelvic indexes have been helpful in diagnosing the syndrome. For Korean cases, however, no definitive data are available as yet, prompting us to evaluate the pelvic changes in Korean Down's patients. Methods : Subjected to this study were 68 children with Down's syndrome. As...
Trend of Tuberculous Meningitis since 1970
Jeong A Park, Chang Weon Oh, Kyoung Sim Kim, Yong Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1996;39(11):1527-1537.   Published online November 15, 1996
Purpose : The incidence of tuberculous meningitis has reportedly decreased from 4.2% in 1970 to 1.8% in 1990 in Korea; however, tuberculous meningitis, which spreads hematogenously, claiming majority of mortality in childhood tuberculosis, still poses serious problems. This study was performed to evaluate the recent trend of tuberculous meningitis. Methods : We compared with three groups of tuberculous meningitis, two were our previous reports on...
Changes in MaternalAge and the Incidence of Down Syndrome
Chang Weon Oh, Sung Su Lim, Ki Bok Kim, Won Jin Kee
Clin Exp Pediatr. 1996;39(11):1512-1519.   Published online November 15, 1996
Purpose : The incidence of Down syndrome, the most common chromosoaml anomaly, increases with the advanced maternal age. Recently, however, the incidence of Down symdrome was reported to have decreased with wide acceptance of prenatal diagnosis and planned parenthood, prompting us to re-evaluate the incidence of Down syndrome in relation to changes in maternal age. Methods : Subjected to study were 296 Down cases: 26...
Study on Platelet Countsand Indices in Neonates
Kyoung Hee Choi, Sung Soo Rim, Byung Min Moon, Ki Bok Kim
Clin Exp Pediatr. 1996;39(3):338-345.   Published online March 15, 1996
Purpose : The platelet number alone does not give a complete picture of platelet maturity and function, therefore, the platelet indices have been the subject of intensive study in recent years, but they have not been firmly established in the neonates. Methods : Blood samples collected in K2 EDTA bottle from femoral vein of 176 neonates (54 healthy fullterm, 96...
Case Report
Arthrogryposis Multiplex Congenita in Siblings
Kyoung Hee Choi, Jeong Ah Park, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1995;38(9):1293-1298.   Published online September 15, 1995
Arthrogryposis multiplex congenita is a rare congenital disorder characterized by multiple fixed-joint deformities of the upper and lower extremities. Most cases are sporadic, although rare cases of familial recurrence are reported worldwide. Recently, we experienced 2 cases of arthrogryposis multiplex congenita in a family (a brother and a sister). They were born with micrognathia, low set ears, broad and short...
Clinical Evaluation of Unmarried Maternal Neonates Admitted to NICU
Chang Weon Oh, Suk Hyun Lee, Kyoung Sim Kim, Ki Bok Kim
Accepted January 1, 1970  
Purpose : This study was done to see whether neonates born to unmarried mothers have higher rates of prematurity, low birth weight, perinatal morbidity and mortality than normal married group. Methods : 88 neonates of unmarried mothers who were admitted in our NICU during the 5-year period from January 1987 through December 1991 were evaluated, and as the control gro-up served...
Case Report
A Case of Acrodysostosis
Suk Hyun Lee, Chang Won Oh, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1995;38(1):133-137.   Published online January 15, 1995
Acrodysostosis is a rare multiple congenital malformation syndrome with peripheral dysostosis, nasal hypoplasia, mental retardation and growth failure. In 1968, Maroteaux and Malamut first described this disorder in three patients, and thus far now over 30 published cases have been reported worldwide. Radiographic changes include severe shortening of metacarpals, metatarsals, and phalages, cone-shaped epiphyses of the hands and feet, premature fusion...
Original Article
Normal Blood TSH, T4 Levels in Neonates as Determined by Screening Test
In Ah Cha, Kwang Sin Kim, Kyoung Sim Kim, Young Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1994;37(6):832-841.   Published online June 15, 1994
In 1,146 term neonates without perinatal problems who were born in kwangju Christian Hospital, blood TSH levels were measured by immunoradiometric assay. In 397 term neonates among them, blood T4 levels were measured by radioimmunoassay in same specimens. 1) In normal neonates aged 3~5days, 6~10days, 11~20days and 21~28days, the TSH levels were 8.885.21(meanSD), 9.44¡¾5.16, 9.69¡¾4.98, 11.963.75IU/ml and the T4 levels were...
Normal Predicted Values of Pulmonary Function Test in children
In Ah Cha, Kwang Sin Kim, Young Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1994;37(5):672-688.   Published online May 15, 1994
An objective evaluation of the degree of respiratory impairment in children depends on the establishment of standards of normal function. In addition to sex and growth, various factors such as race and geography have been shown to be important determinants of lung function. The purposes of this paper are to report the result of lung function tests performed on a...
A Clinical Study on Twins
Kwang Sin Kim, In Ah Cha, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1994;37(4):537-546.   Published online April 15, 1994
We observed 233 twins and 2 triplets cases among 16,774 newborns delivered at Kwangju Christian Hospital during 5 years from Jan. 1986 to Dec. 1990. The results obtained are as follows : 1) The overall incidence of twin pregnancy was 1 : 72 (1.4%) and that of triplets 1 : z8387 (0.01%). 2) The average male-female sex ratio of twins was 1.06 :...
Ultrasonographic Diagnosis of Congenital Hypertrophic Pyloric Stenosis
Chung Hyun Yun, Kwang Sin Kim, Young Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1994;37(4):494-501.   Published online April 15, 1994
Ultrasonic evaluation of the pylorus was performed in a group of 22 infants clinically suspected of having Congenital Hypertrophic Pyloric Stenosis (CHPS), from march 1990 to July 1991. In every case the diagnosis of CHPS was confirmed by surgery. Ten normal babies served as the control group. 1) In CHPS group, the mean age on admission was 36.7¡¾16.4 days, and male...
Case Report
A Case of Monozygotic Twin with Dwn Syndrome
Seong Heon Jeon, Choong Hyun Yoon, Young Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1993;36(3):434-438.   Published online March 15, 1993
Down syndrome is the most common autosomal chromosomal abnormality characterized by mental and growth retardation, and by various typical features including prominent epicanthal fold, oblique palpebral fissure, flat nasal bridge, short and broad hand, wide toe interspace, etc. The overall incidence has been shown to be 1:800 deliveries, increasing with advancing maternal age. However, twin cses are extremely rare, and...
Original Article
Significance of Brain CT in Children with Chief Complaints of Neurological Symptoms and Signs of Intracranial Disorders
Chun Ho Cho, Chung Hyun Yoon, Young Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1992;35(6):753-761.   Published online June 15, 1992
Because of its accuracy, rapidity as well as non-invasiveness, brain CT (computerized transaxial tomography)is being widely used as the most reliablel diagnostic approach for neurologic disorders in childhood. Brain CT provides good anatomic configuration of the brain and its gross disease processes that have as a manifestation alteration in brain density, disturbance in blood-brain barrior, or mass effect etc. We evaluated...
Clinical Study on 44 Cases of Infant Born to Polyhydramniotic Mother
Byung Min Moon, Chun Ho Cho, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1992;35(5):630-638.   Published online May 15, 1992
Forty four cases of Polyhydramnios were studied clinically among 13,337 newborn infants delivered in Kwangiu Christian Hospital during the period from April 1, 1986 through March 31, 1990. 1) The incidence of polyhydramnios was 0.33%. 2) The mean gestational age was 37.2 week, and 18 cases(40.8%)were premature, while 3 babies (6.8%) were born postmaturely. 3) The mean birth weight was 2.3kg, with 30...
The Incidence of Hypothyroidism in Children with Down Syndrome
Seong Hyeon Jeon, Chun Ho Cho, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1992;35(4):534-538.   Published online April 15, 1992
A review of Thyroid function tests was performed on 32 children with Down syndrome confirmed by cytogenetic examination at the Dept. of Pediatrics, Kwangju Christian Hospital from Jan.1989 to Feb.1990. 1) Twenty among 32 children with Down syndrome were male, with the sex ratio being 1.7 : 1. Their ages ranged from 3 days to 5 years, with the mean age...
Clinical studies of meningitis cases in children.
Chun Oh Lee, Song Nyeon Choi, Yong Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1991;34(2):206-216.   Published online February 28, 1991
A clinical studies were carried out on 442 cases who were admitted to the Department of Pediatrics, Kwangju Christian Hospital under impression of meningitis during a 7 year period form January, 1982 to December, 1989. The results are summerized; 1) No yearly fluctuation in incidence for both purulent and aseptic meningitis was noted, but decreasing tendency was clearly seen for tuberculous meningitis. 2) Purulent meningitis affected mostly babies...
A clinical study on goiter in childhood.
Yeong Hee Chung, Byung Min Moon, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1991;34(1):83-94.   Published online January 31, 1991
A clinical study was done on 96 cases of goiter in children which were diagnosed at pediatric department of Kwangju Christian Hospital during the period form January 1985 to December 1988. The observed clinical data were summarized as follows: 1) Preponderately femalels were affected with the sex ratio of 1:6.7. The majority of cases (78.2%) were around puberty. 2) On physical examination, 59 cases (85.5%) were found...
A Case of Hypohydrotic Ectodermal Dysplasia.
Chun Oh Lee, Byung Min Moon, Young Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1990;33(12):1718-1722.   Published online December 31, 1990
Hypohidrotic ectodermal dysplasia is a group of disorders characterized characterized by faulty development of ectodermal structures including the skin, teeth, skin appendages, resulting in hypohi- drosis, hypotrichosis, and abnormal dentition. Here, we report a case of typical hypohidrotic ectodermal dysplasia in a 16-month-old male who had unexplained recurring fever, hypohidrosis, hypotrichosis, anodontia, and characteristic facial features.
Statistical Survey on Pediatric patients admitted to Kwangju Christian Hospital during 5 years.
Song Nyeon Choi, Young Hee Chung, Young Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1990;33(11):1479-1488.   Published online November 30, 1990
We made a statistical survey on the patients admitted to the Department of Pediatrics of Kwangju Christian Hospital during the past 5 years from Jan. 1984 to Dec. 1988 The results were as follows: 1) The pediatric inpatients during the period totaled 16,119, of which 10,020 were male, with the sex ratio being 1.6:1. 2) Pediatric patients amounted to 17.8% of all admission cases of Kwangju Christian...
Statistical Study on Pediatric Emergency Patients.
Boyoung Hong Ahn, Young Hee Chung, Young Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1990;33(3):283-290.   Published online March 31, 1990
An analysis was carried out on the pediatric patients who visited the emergency room of the Kwangju Christian Hospital during the three-year-period from Jan. 1985 to Dec. 1987. The results were as follows: 1) Out of 27,610 total emergency patients, 9,784 (35.8%) were under 15 years of age. 2) The male-to-female ratio was 1.6:1. 3) The peak incidence was found among children aged between 1 month to 11...
A Case of Cornelia de Lange syndrome.
Byoung Hong Ahn, Song Nyeon Choi, Young Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1990;33(2):234-240.   Published online February 28, 1990
We have experienced a case of Cornelia de Lange syndrome in a 3-year-old boy. The patient showed most of the typical clinical features of the syndrome: microcephaly, bushy eyebrows and synophys, antimongolian slant, small nose and anteverted nostrils, thin protruding lips with downturning of the comer, micrognathia, low set ears, generalized hirsuitism, and growth redardation. The patient also had skeletal abnormalities of hands. Chromosomal...
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