Purpose : The aim of this study was to determine the reference ranges of serum albumin levels depending on the gestational ages of preterm infants. We also intended to compare the mean serum albumin levels between groups of preterm infants that did not develop clinical disorders later, and groups that did develop clinical disorders such as respiratory distress syndrome, intraventricular... |
Purpose : The incidence of obesity has increased in Korea recently. Obesity leads to higher risks of hypertension, hyperlipidemia and insulin resistance. It also leads to risks of respiratory complications. This study was performed to see the effects of obesity on children's pulmonary functions and on developed bronchospasm after exercise loading according to their obesity degrees. Methods : 257 obese... |
Purpose : This study aimed to determine the amino acids composition, safety and efficacy of formulas recently developed by Korean dairy companies for children with inherited metabolic disorder. Methods : The determination of amino acids concentration was performed on eight Korean formula samples. The samples were hydrolyzed with 6N HCL or performic acid and analyzed by amino acid analyzer. Results : No phenylalanine, methionine or... |
Purpose : Recently, the numbers of non-pediatric doctors' giving medical treatment to children has shown a tendency to increase, especially in case of upper respiratory infection(URI) and it's complications such as tonsillitis, sinusitis and otitis media. Therefore we surveyed parents on children's URI and complications to find out parents' general understandings on pediatric treatment, what kind of pediatric treatment they... |
The authors report a 7-year-old boy with neuroblastoma complicated by severe hypertension and pulmonary edema. Abdominal computed tomographic scan revealed a huge mass surrounding the aorta. After administration of cancer treatment, there was a marked increase in serum catecholamines level and hypertension, which resulted in pulmonary edema and heart failure. Alpha adrenergic blocking agents(prazocin, terazocin) were administrated, successfully controlling the... |
Graves' disease is a relatively rare endocrinologic disorder in childhood age and often associated with other endocrinologic disorders such as type I diabetes mellitus and Addison's disease etc. Also, it is associtated with non-endocrinologic autoimmune diseases such as systemic lupus erythematosus, myasthenia gravis, idiopathic thrombocytopenic purpura, vitiligo and pernicious anemia. However, idiopathic hypoparathyroidism associated with Graves' disease is very... |
Lymphoid interstitial pneumonia(LIP) is an uncommon process in childhood, and is characterized by interstitial accumulation of mature lymphocytes, plasma cells and reticuloendothelial cells. LIP is believed to have autoimmune or immunologic pathogenesis, because it is frequently associated with acquired immune deficiency syndrome, Epstein-Barr virus infection, common variable immunodeficiency. The patient described in this report had idiopathic thrombocytopenic purpura, Evans syndrome... |
Multicystic encephalomalacia is the condition defined anatomically by the presence of multiple cavities in the great part of both cerebral hemispheres. The most common cause of the condition was regarded as the circulatory disturbance during the perinatal period. Also,neonatal asphyxia was the most important cause of the circulatory disturbance. But we experienced a case of multicystic encephalomalacia in a liveborn twin with a stillborn... |
Narcolepsy is a serious, lifelong, disabling disorder characterized by a tetrad of symptoms including excessive daytime sleepiness, cataplexy, hypnagogic hallucination, and sleep paralysis. We experienced a 14 year old boy with a narcolepsy diagnosed by typical clinical symptoms above mentioned and multiple sleep latency test. A brief review of the related literatures was also made. |
Purpose : Most patients suffer from croup only once in a life time. However, a small group of patients suffer from it several times. A type of croup from which they suffer more than 3 times is called recurrent croup. The cause of recurrent croup has not been clearly described, but in recent years the allergic reaction is considered as a... |
The cholelithiasis and common bile duct(CBD) stone are rare problems among children. Endoscopic retrograde cholangiopancretogram(ERCP) and endoscopic sphincterotomy are rarely commomly utilized in the treatment of children, primarily because there are fewerindications. ERCP is an established procedure for visualization of the biliary tract. Endoscopic sphincterotomy with stone extraction has been accepted as the treatment of choice for CBD stone removal in adults. However, the role... |
Pneumoperitoneum in the newborn is usually a surgical emergency resulting from gastroint-estinal perforation. However, pneumoperitoneum can occur secondary to a pulmonary air leak which progresses from the mediastinum to the retroperitoneum by way of perivascular spaces and then to the peritoneum following rupture. We have observed this phenomenon in three ventilated newborn. A brief review of the related literatures was... |
We experienced a case of eisenmenger syndrome treated by simple surgical intervention. Eisenmenger syndrome refers to patients with congenital heart defects who have a systemic level of pulmonary arterial pressure and high pulmonary vascular resistance, with right-to-left or bidirectional shunting. Because a progressive rise in pulmonary vascular resistance may be better tolerated with an intracardiac communication, surgical repair in such patients... |
This study was taken to measure the serum aminotransferase level and it's correlation with clinical symptoms from Human Rotavirus gastroenteritis. This report is based on analysis of 434 patients who were admitted to the Pediatric department at Wonju Christian Hospital because of watery diarrhea and vomiting during 2-year period from July, 1991 to June 1993. The stool specimen on admission... |
Isolated angiitis of the central nervous system is a rare clinicopathologic entity characterized by vasculitis restricted to the vessels of the central nervous system without other apparent systemic vasculitis. It manifests headache, higher cortical dysfunction, focal neurologic dysfunction and cranial nerve palsies. We experienced a case of isolated angiitis of the central nervous system in 6 year-old girl who was admitted... |
Brachyecphaly is a kind of craniosynostosis. Because of premature closure of the coronal suture, the skull is shorter in the anteroposterior diameter but is widened with a high vault and the occiput and borehead are flattened. Diabetes insipidus had been reported in oxycephaly. We have experienced a case of central diabetes insipidus associated with brachcephaly. A brief review of related literatures... |
To validate the diagnostic significance of red cell indices in non-anemic iron deficiency and iron deficiency anemia, complete blood count, serum iron, total iron binding capacity, and serum ferritin were measured in 208 middle school girls between 13 and 15 years age. We used Reciever Operating Characteristic (ROC) curve to compare the diagnostic significances of various red cell indices (MCV,... |
Regionalization of high-risk perinatal care has been advocated because intensive care of small and ill newborn infants lowers mortality and morbidity. This report is based on analysis of admissions to the Neonatal Intensive Care Unit (NICU) at the Wonju Christian Hospital during the 4-year period from January, 1988 to December, 1991. There were 786 inborn infants and 1155 outborn... |
Virus associated hemophagocytic syndrome, class II histiocytoses, characterized by high fever, severe constitutional symptoms, abnormal liver function and coagulation, peripheral blood pancytopenia and histiocytic hyperplasis with prominent hemophagocytosis in bone marrow and lymph nodes has been reported and associated with active viral infection. It is non-malignant and reversible. It must be differentiated from histiocytic medullary reticuosis because of the inappropriateness... |
We have experienced a 14 year old female patient who had suffered from headache, dizziness, exertional dyspnea and chest pain during 6 months. She was diagnosed as primary pulmonary hypertension by ultrasonogram and cardiac catheterization. On the cardiac catheterization, there was elevated pulmonary artery pressure and normal pulmonary wedge pressure. We report this case with related literature review. |
We experienced a case of nonbacterial thrombotic endocarditis in a 25-day-old male neonate, who was suffered from ASD, MR and congestive heart failure. He was died suddenly during recovery phase. The Post diagnosis was nonbacterial thrombotic endocarditis. We report with a brief review and its related literatures. |
Acute disseminated encephalomyelitis(ADEM) is an acute inflammatory demyelinating disease of the central nervous system. It is thought to be an autoimmune mediated disorder which occurs usually after viral or bacterial infections, or after immunization. The clinical manifestations reflect sudden onset of the diffuse involvement of the brain, spinal cord and the meninges. We experienced two cases of acute disseminated encephalomyelitis. The... |
While lipomas are common in the rest of the rest of the body, intracranial lipomas are rare condition which are usually found in the midline of the brain. The majority of these lesions show few or even no symptoms and hardly ever produce alarming neurological defects. We experienced a case of corpus callosum lopoma in a 7 year old boy, who... |
This study was conducted to find out the significance of nucleated red blood cell (NRBC) in neonates, especially associated with acute or chronic perinatal asphyxia. So, we compared NRBC counts in various neonatal groups, such as normal newborn, small for gestational age (SGA), premature, acute perinatal asphyxia, & hyaline membrane disease (HMD). In the first day of life, we examined... |
Poststeroid panniculitis occuring after steroid treatment is an extremely rare entity. Multiple subcutaneous, firm, pruritic, tender nodules occur chiefly over the cheeks, arms, and trunk in young children following sudden discontinuation of large dose of steroids. We experiened a case of poststeroid panniculitis in a 2day-old female infant with complaints of multiple subcutaneous nodules on cheeks and neck... |
Tuberculous meningitis is still relatively common infectious disease of central nervous system in korea. The prognosis of tuberculous meningitis is closely related to the state at which treatment if started. Adenosine deaminase (ADA) is an enzyme which irreversibly hydrolyzes adenosine into inosine and ammonia. Recent investigations have suggested that the measurement of ADA activities in cerebrospinal fluid is useful in the... |
L-asparaginase is known as an effective anticancer drug in the induction chemotherapy of acute lymphocytic leukemia. The side effects or toxicities of L-asparaginase and prednisolone are hypersen- sitivity reaction, hepatotoxicity, pancreatitis and transient diabetes mellitus, CNS toxicity, disorder of coagulation system and mild cytotoxicity. We experienced a case of transient diabetes mellitus and diabetic ketoacidosis induced by L- asparaginase, prednisolone, vincristine and MTX administration in... |
Myelofibrrosis is characterized by anemia, leukoerythroblastosis, extramedullary hematopoiesis, hepatosplenomegaly, osteosclerosis and fibrosis of bone marrow. Idiopathc myelofibrosis is usually a disease of the adult and is rare in the pediatric age group. Juvenile xanthogranuloma is characterized by multiple papules on forehead and scalp. Lipid laden histiocytes and Touton giant cell are found in skin biopsy. We experienced a case of myelofibrosis with juvenile xanthogranuloma.... |
Citrobacter although once regarded as nonpathogenic, has been responsible for many well- documented pathologic conditions, especially in compromised hosts. These include urinary tract, pulmonary and bone infections, gastroenteritis, gangrenous ulcer with septicemia, meningitis, and brain abscess. Citrobacter organisms have a mosaic of 0, K and H antigens that are found in the Enterobacter- iaceae. Cross reactions with antisera of other members of the Enterobacteriaceae suggest... |