Clinical and Experimental Pediatrics

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Original Article

Utility of a multiplex reverse transcriptase-polymerase chain reaction assay (HemaVision) in the evaluation of genetic abnormalities in Korean children with acute leukemia: a single institution study

Hye-Jin Kim, Hyun Jin Oh, Jae Wook Lee, Pil-Sang Jang, Nack-Gyun Chung, Myungshin Kim, Jihyang Lim, Bin Cho, Hack-Ki Kim

Clin Exp Pediatr. 2013;56(6):247-253. Published online June 21, 2013

Crossref 6

Purpose

In children with acute leukemia, bone marrow genetic abnormalities (GA) have prognostic significance, and may be the basis for minimal residual disease monitoring. Since April 2007, we have used a multiplex reverse transcriptase-polymerase chain reaction tool (HemaVision) to detect of GA.

Methods

In this study, we reviewed the results of HemaVision screening in 270 children with acute leukemia, newly diagnosed at The...

DOI: https://doi.org/10.3345/kjp.2013.56.6.247

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