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Case Report
Congenital miliary tuberculosis in an 18-day-old boy
Jue Seong Lee, Chang Hoon Lim, Eunji Kim, Hyunwook Lim, Yoon Lee, Ji Tae Choung, Young Yoo
Clin Exp Pediatr. 2016;59(Suppl 1):S64-S67.   Published online November 30, 2016

Congenital tuberculosis (TB) is a rare disease that is associated with high mortality. Mycobacterium tuberculosis, the causative agent, may be transmitted from the infected mother to the fetus by the transplacental route or by aspiration of infected amniotic fluid. Clinical symptoms and signs are not specific. Miliary patterns are the most common findings in the chest X-rays of many infants...

Original Article
Predictive value of C-reactive protein in response to macrolides in children with macrolide-resistant Mycoplasma pneumoniae pneumonia
Young Ho Seo, Jang Su Kim, Sung Chul Seo, Won Hee Seo, Young Yoo, Dae Jin Song, Ji Tae Choung
Clin Exp Pediatr. 2014;57(4):186-192.   Published online April 30, 2014

The prevalence of macrolide-resistant Mycoplasma pneumoniae (MRMP) has increased worldwide. The aim of this study was to estimate the proportion of MRMP in a tertiary hospital in Korea, and to find potential laboratory markers that could be used to predict the efficacy of macrolides in children with MRMP pneumonia.


A total of 95 patients with M. pneumoniae pneumonia were enrolled in...

Case Report
Idiopathic acute eosinophilic pneumonia in a 14-month-old girl
Ha Neul Park, Bo Hyun Chung, Jung Eun Pyun, Kwang Chul Lee, Ji Tae Choung, Choon Hak Lim, Young Yoo
Clin Exp Pediatr. 2013;56(1):37-41.   Published online January 29, 2013

Idiopathic acute eosinophilic pneumonia (IAEP), characterized by acute febrile respiratory failure associated with diffuse radiographic infiltrates and pulmonary eosinophilia, is rarely reported in children. Diagnosis is based on an association of characteristic features including acute respiratory failure with fever, bilateral infiltrates on the chest X-ray, severe hypoxemia and bronchoalveolar lavage fluid >25% eosinophils or a predominant eosinophilic infiltrate in lung...

Original Article
CD4+/CD8+ T lymphocytes imbalance in children with severe 2009 pandemic influenza A (H1N1) pneumonia
Ji Eun Kim, Siegfried Bauer, Kyong Suk La, Kee Hyoung Lee, Ji Tae Choung, Kyoung Ho Roh, Chang Kyu Lee, Young Yoo
Clin Exp Pediatr. 2011;54(5):207-211.   Published online May 31, 2011

This study was conducted to investigate the immune responses of children with moderate and severe novel influenza A virus (H1N1) pneumonia, and to compare their clinical and immunological findings with those of control subjects.


Thirty-two admitted patients with H1N1 pneumonia were enrolled in the study. The clinical profiles, humoral and cell-mediated immune responses of the 16 H1N1 pneumonia patients who were...

Case Report
Isolated pulmonary cryptococcosis in an immunocompetent boy
Siegfried Bauer, Ji Eun Kim, Kyong Suk La, Young Yoo, Kee Hyoung Lee, Sang Hee Park, Ji Tae Choung, Chul Whan Kim
Clin Exp Pediatr. 2010;53(11):971-974.   Published online November 30, 2010

Pulmonary cryptococcosis is rare in immunocompetent subjects. Here, we present the case of a 16-year-old boy who was referred to our pediatric department for the management of multiple consolidations detected on chest radiography, which was routinely performed when the patient was being evaluated for an ankle fracture. Fine needle aspiration biopsy was performed, and the definitive diagnosis was established as...

Original Article
Caregivers’adherence factors affecting maintenance treatment in children with well-controlled asthma : A qualitative analysis through in-depth interview
Ic Sun Choi, Saeng Koo Cho, Kyong Suk La, Jung Hye Byeon, Dae Jin Song, Young Yoo, Ji Tae Choung
Clin Exp Pediatr. 2010;53(3):364-372.   Published online March 15, 2010
Purpose : Good adherence of caregivers is essential for successful health outcomes in the treatment of childhood asthma. The purpose of this study was to identify the factors contributing to good adherence of maintenance treatment in children with well-controlled asthma. Methods : Children with well-controlled asthma being treated with a daily controller for at least 3 months in Korea University...
Effects of inhaled corticosteroids on bone mineral density and bone metabolism in children with asthma
Ic Sun Choi, Jung Hye Byeon, Seung Min Lee, Kyong Suk La, Yeon Joung Oh, Young Yoo, Kee Hyoung Lee, Ji Tae Choung
Clin Exp Pediatr. 2009;52(7):811-817.   Published online July 15, 2009
Purpose : Inhaled corticosteroids (ICS) are used as first-line agents for the treatment of persistent asthma; however, their use is accompanied by apprehension of potential systemic adverse effects. This study aimed to assess the effects of ICS on bone mineral density (BMD) and bone metabolism in children with asthma. Methods : From February 2008 to September 2008, 26 asthmatic children treated...
Increased vascular endothelial growth factor in children with acute Mycoplasma pneumoniae pneumonia and wheezing
Young Seo, Byung Keun Yu, Yeon Joung Oh, Yoon Lee, Young Yoo, Ji Tae Choung, Young Yull Koh
Clin Exp Pediatr. 2008;51(5):487-491.   Published online May 15, 2008
Purpose : Although Mycoplasma pneumoniae (M. pneumoniae) infection can cause wheezing in non-asthmatic children, the mechanisms of this symptom remain unclear. Vascular endothelial growth factor (VEGF) is a major mediator of angiogenesis and vascular permeability, and is also known to be elevated in cases of chronic pulmonary disease such as asthma. We hypothesized that VEGF may increase in children with...
Effects of an intensive asthma education program on asthmatic children and their caregivers
Kang Jin Seo, Gun Ha Kim, Byung Keun Yu, Yun Ku Yeo, Jong Hoon Kim, Eu Ddeum Shim, Mi Ri Yoon, Young Yoo, Ji Tae Choung
Clin Exp Pediatr. 2008;51(2):188-203.   Published online February 15, 2008
Purpose : Asthma is one of the most common chronic childhood disease. Education of asthmatic children and their families about asthma and its management may improve disease control, reduce symptoms, and improve school performance. The aim of the study was to evaluate the effects of an intensive asthma education program in asthmatic children and their families on outcome measure...
Case Report
Three cases of pulmonary and/or intestinal tuberculosis in adolescents
Jung Hye Byeon, Yoon Lee, Jin Chul Lee, Young Yoo, Kee Hyoung Lee, Kwang Chul Lee, Ji Tae Choung, Soo Youn Ham, Chul Whan Kim
Clin Exp Pediatr. 2007;50(11):1134-1138.   Published online November 15, 2007
Since the tuberculosis (TB) in adolescents has unique clinical characteristics, special attention should be paid to this age group. Adolescents are more susceptible to developing TB disease and more likely to have cavitary pulmonary disease. Also, adolescent patients with TB more frequently present with extrapulmonary disease. We report three adolescents with active pulmonary and/or intestinal TB: one had pulmonary and...
Original Article
Health and risk taking behaviors of freshmen in college
Hong Ki Ko, Jae Joon Han, Yoon Lee, Young Yoo, Kee Hyoung Lee, Ji Tae Choung, Sang Hee Park
Clin Exp Pediatr. 2006;49(10):1042-1049.   Published online October 15, 2006
Purpose : This study was conducted to survey the preliminary data on risk behaviors and to identify the factors that prevent risk-behaviors in late adolescence. Methods : Freshmen(n=1,297) beginning the first semester in Korea University, Seoul, Korea completed self-administered risk behavior questionnaires, comprising 5 domains : demographics, smoking, drinking, drug abuse and sexual behavior. Results : The rate of smoking experience was...
Smoking Adolescents' Acquisition of Cigarettes and Status of Proof of Age
Hee Ra Kim, Ji Young Kim, Gee Hyung Lee, Ji Tae Choung, Sang Hee Park
Clin Exp Pediatr. 2005;48(4):363-368.   Published online April 15, 2005
Purpose : The aim of this study is to identify where and how adolescents acquire cigarettes and how many were asked for identification while purchasing cigarettes. Methods : This study was conducted in 2003; participants were 2,200 students in middle and high schools, aged from 13 to 18 years old(males 1,098; females 1,102) in Ansan, Korea. The questionnaire assured them of...
Case Report
Two Cases of Kabuki Make-up Syndrome Including One Case Associated with Xq Isochromosome
Ki Hea Cho, Jung Hwa Lee, Kee Hyoung Lee, Kwang Chul Lee, Ji Tae Choung, Chang Sung Son, Young Chang Tockgo
Clin Exp Pediatr. 2000;43(8):1111-1115.   Published online August 15, 2000
Kabuki make-up syndrome(KMS) is characterized by mental and developmental retardation and peculiar facial features including long palpebral fissures with eversion of the lateral portion of lower eyelid and arching of eyebrows, resembling the actors in Japanese Kabuki. In addition, dermatoglyphic and skeletal abnormalities are commonly associated. Although most karyotypes of KMS are shown to be normal, there have been some...
Original Article
Mumps and Rubella-Specific IgG Levels of Term Pregnant W omen and Their Neonates
Young Kyoo Shin, Hae Won Cheon, Kee Hyoung Lee, Ji Tae Choung, Young Chang Tockgo
Clin Exp Pediatr. 1998;41(1):47-52.   Published online January 15, 1998
Purpose : This study was performed to evaluate seropositivities in term pregnant women and their neonates, and the transplacental transfer rate of maternal mumps and rubella- specific IgG from term pregnant women to their neonates. Methods : During Jun. 1, 1994 to Mar. 31. 1995, we collected 44 pairs of sera from pregnant women and their neonates in Anam Hospital of Korea University Medical...
Measles Specific IgG Antibody Level of Term Pregnant Women and Neonatal Umbilical Cords
Hee Yeon Park, Young Kyoo Shin, Ji Tae Choung, Young Chang Tockgo
Clin Exp Pediatr. 1996;39(9):1224-1230.   Published online September 15, 1996
Purpose : Despite appropriate preventive measures, measles outbreaks occurred in the year of 1989-1990 and 1994 in Korea. Especially, the ratio of young infantile patients below 15 months old was high in those outbreaks, and the reason was, we thought, low serum level of measles specific IgG antibody in pregnant women and low transplacental transfer rate of measles specific IgG antibody to neonate. This...
Clinical Lecture
Diagnosis and Treatment of Chronic Cough
Ji Tae Choung
Clin Exp Pediatr. 1996;39(3):313-318.   Published online March 15, 1996
Case Report
Two Case of Dyke-Davidoff-Masson Syndrome
Dong Gun Park, Ji Hee Park, Kee Hwan Yoo, Ji Tae Choung, Chang Sung Son, Young Chang Tockgo
Clin Exp Pediatr. 1993;36(6):865-869.   Published online June 15, 1993
Dyke-Davidoff Masson syndrome is a rare disorder which developed hemiatrophy of brain, enlargement of ventricles and prominet pneumatrization of pertous pyramid of the temporal bone. It manifests hemiparesis, varying type seizure, and mental retardation. We experienced two cases of Dyke-Davidoff-Masson Syndrome, in a 6/12 year-old boy and a 1,10/12 year-old girl who were admitted to our department of pediatrics, because of...
Original Article
Conjoined Thoracopagus Twins.
Min Young Lee, Young Yoo, Ji Tae Choung, Joo Won Lee, Young Chang Tockgo, Yang Seouk Chae
Clin Exp Pediatr. 1990;33(5):671-674.   Published online May 31, 1990
Conjoined twins are very rare congenital malformation in which twins have varying degree of anatomical union. The conjoined twins seems preferable to such as craniopagus, thoracopagus, ischiopagus and pyopagus. Because of their associated anomalies, particularly of cardiovascular system, and difficulties in delivery, they usually survive only short postnatal period. Successful surgical separation and long term survival would have been achieved in a small numbers...
Serum LDH and Isoenzyme Activity in Children with Respiratory Diseases.
Kyoung Min Ann, Young Kyoo Shin, Kwang Chul Lee, Ji Tae Choung, Young Chang Tockgo, Pyung Hwa Choe
Clin Exp Pediatr. 1989;32(8):1051-1056.   Published online August 31, 1989
LDH which are widely distributed in mammalian tissues, being rich in myocardium, kidney, liver and muscle, and which is well known to catalyzes the reversible oxidation of lactate to pyruvate. We investigated serum LDH & Isoenzyme changes in 317 cases of children with respiratory disease and in 117 cases of healthy children as control. The objectives of this study were to ascertain whether serum...
A Case of Congenital Neuroblastoma.
Kee Hyung Lee, Baik Lin Eun, Kwang Chul Lee, Ji Tae Choung, Toung Chang Tockgo, Yang Seok Chae
Clin Exp Pediatr. 1988;31(6):803-808.   Published online June 30, 1988
Neuroblastoma is one of the most common malignancy in infancy & childhood, but congenital neuroblastoma is rare. We experienced a case of congenital neuroblastoma of right posterior mediastinum without metastasis in 10-day-old female neonate. The diagnosis was established by autopsy including gross and microscopic finding. A brief review of literatures was made.
Clinical Study of 12 Cases of Korean Hemorrhagic Fever in Childhood.
Dae Kyung Ko, Keyun Haeung Cho, Ji Tae Choung, Pyung Hwa Choe
Clin Exp Pediatr. 1987;30(8):837-845.   Published online August 31, 1987
Korean hemorrhagic fever (KHF) is an acute, rodent-bom, viral illness (Hantaanvirus) which is characterized by widespread abnormalities of blood vessels, chiefly arterioles and capillaries. The vascular abnormaliteis lead to impairment of function in a number of organs with resulting bleeding tendency and renal failure. KHF was recognized for the first time in Korea in 1951. In recnt years the disease has invaded the southern parts...
Zinc and Copper Contents in Infant Formula.
Ji Tae Choung, Hyun Keum Lee
Clin Exp Pediatr. 1987;30(8):831-836.   Published online August 31, 1987
In 22 samples of infant formula, marketed in Korea, from Apr. 1986 to Oct. 1986, trace elements especially Zn and Cu levels were examined by Atomic Absorption Spectrophotometer. The results were as follows; 1) B-milk, zinc supplemented, contained Zn 863.23 ±50.52 ㎍/100 g, there were no relations with manufacturing date. 2) A-milk and C-milk contained variable levels from absent to 641.19 ㎍/100 g in Zn, 20.02㎍/100g in...
Case Report
Acute isoniazid poisoning in childhood.
Ji Tae Choung, Jun Tae Park, Jee Kyu Lee, Kyu Eun Lee
Clin Exp Pediatr. 1982;25(9):959-962.   Published online September 30, 1982
Sin:e tae introiucdon of isoniazid in ;1952, periodic reports of intentional or accidental intoxications complicate! by generalize! convulsions have appeared. Only 31 cases, to our knowlelge, have reportei in English literature until 1980 in pediatric age group. In Korea, oily two cases of a?ite isoniazid intoxication in childhood reported, although there are high incideiee of T.B. ani frequent use of isoniazid. We have experienced...
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