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Original Article
Risk factors associated with complicated methicillin-resistant Staphylococcus aureus bacteremia in neonates
Young Jin Lee, Hyen Jin Kim, Shin Yun Byun, Su Eun Park, Hee Ju Park
Clin Exp Pediatr. 2010;53(2):173-177.   Published online February 15, 2010
Purpose : Methicillin-resistant Staphylococcus aureus (MRSA) is an important pathogen that causes nosocomial infection in NICU. It contributes to neonatal morbidity and mortality with variable complications. This study was conducted to identify the risk factors associated with complicated MRSA bacteremia in neonates. Methods : We reviewed the medical records of 44 neonates with positive blood culture for MRSA who were admitted...
Case Report
A case of hepatopulmonary syndrome in a child with fatty liver disease secondary to hypopituitarism after craniopharyngioma resection
Sun Ju Im, Hyun Seok Park, Hyoung Doo Lee, Jae Hong Park, Hee Ju Park
Clin Exp Pediatr. 2007;50(8):794-798.   Published online August 15, 2007
Hepatopulmonary syndrome is a triad that includes: hepatic dysfunction, intrapulmonary vascular dilatation and abnormal arterial oxygenation. The incidence of intrapulmonary vascular dilatations, in adults with end-stage liver disease, has been reported to be 13% to 47%, however the incidence in children is unclear and the cases in Korean children have never been reported. The hepatopulmonary syndrome may occur as a...
Original Article
Screening Test for Heart Diseases in the First Grade Elementary School Children in Busan
Jae Min Oh, Hee Ju Park
Clin Exp Pediatr. 2003;46(5):490-494.   Published online May 15, 2003
Purpose : We'd like to determine the incidence of congenital heart disease and arrhythmia in elementary school children in Busan, and to provide adequate prevention and treatment. Methods : A total of 23,802(male 12,909, female 10,893) 1st grade elementary school children living in Busan were studied. All children were 7-8 years old. We obtained their medical history by questionnaire and checked...
Clinical Analysis of Atypical Kawasaki Disease : Comparison of Kawasaki Disease Between Typical and Atypical Types
Eun Ju Jeong, Jae Hong Park, Hee Ju Park
Clin Exp Pediatr. 2001;44(12):1448-1453.   Published online December 15, 2001
Purpose : Kawasaki disease(KD) is known as one of the most important causes of acquired heart disease in children. But the incidence of acquired heart disease can be reduced by early diagnosis and treatment with large amounts of intravenous γ-globulin(IVGG). For early diagnosis and treatment of atypical KD, we analyzed and compared the clinical features, laboratory findings and coronary lesions in patients with typical...
The Study of the Changes of Myocardial Histology and Left Ventricular Function according to the Total Doses of Doxorubicin in Rabbits
Jeong Hwa Choi, Hee Ju Park, Young Tak Lim, Bong Seon Kim, Eun Young Huh
Clin Exp Pediatr. 2001;44(12):1395-1403.   Published online December 15, 2001
Purpose : We'd like to evaluate the relationship between the degree of cardiac damage and that of cardiac function according to the total injected dose of doxorubicin. Methods : 12 rabbits(body weight : 2.0-3.2 kg) were used and 30 mg/m2/week of doxorubicin hydrochloride was injected intravenously. The cardiac function was checked under anesthesia, after which the thorax was opened and cardiac samples were evaluated...
The Relationship between Change of Cardiac Function and Systemic Oxygen Consumption according to the Dose of Dopamine in the Rabbit
Hee Ju Park, Seok Ho Yoon, Bong Seok Choi, Jung Hwoi Cho, Ku Tae Kim, Sun Young K, Sang Ook Nam, Bok Luel Lee
Clin Exp Pediatr. 2001;44(2):177-184.   Published online February 15, 2001
Purpose : We'd like to know the relationship between the changes of cardiac function and systemic O2 consumption according to the increasing dose of dopamine. Methods : Ten rabbits(from 2kg to 2.8kg) were used in this experiment. Anesthesia was induced with intraperitoneal pentobarbital sodium(35mg/kg) and tracheostomy was done. It was maintained by ventilation with a mixture of 1-3% halothane and 67-69%...
Case Report
A Case of Fibromuscular Dysplasia Associated with Hypertensive Encephalopathy
Ju Suk Lee, Sang Nam Bae, Sang Ook Nam, Su Young Kim, Hee Ju Park
Clin Exp Pediatr. 2000;43(5):715-719.   Published online May 15, 2000
Fibromuscular dysplasia is the single leading etiology of renovascular hypertension in children. We report an eight-year-old girl who was admitted for generalized tonic seizure with fibromuscular dysplasia of right renal artery. On admission, she presented hypertension and altered mentality. She had suffered from intermittent severe headache for the past year. Renal angiography of right renal artery showed stenosis, beaded pattern...
A Case of Infantile Marfan Syndrome
Sun Young Kim, Hee Ju Park
Clin Exp Pediatr. 1999;42(11):1583-1588.   Published online November 15, 1999
Marfan syndrome is infrequently diagnosed early in infancy. The morphologic characteristics and prognosis in infantile Marfan syndrome may be quite different from those in older patients. Characteristic cardiac findings in early life include mitral valve prolapse, valvular regurgitation, and aortic root dilation. Morbidity and mortality may be high for infants diagnosed with Marfan syndrome. Cardiac surgery for cardiovascular complication in...
A Case of Neonatal Myocardial Infarction with Structurally Normal Coronary Arteries
Ju Eun Lee, Seong Shik Park, Su Young Kim, Hee Ju Park
Clin Exp Pediatr. 1999;42(10):1459-1463.   Published online October 15, 1999
A Case of Isolated Right Ventricular Hypoplasia without Tricuspid Atresia or Pulmonary Atresia
Eui Jun Yang, Sun Young Kim, Sank Ook Nam, Hee Ju Park, Nam Hee Kwak
Clin Exp Pediatr. 1999;42(7):1026-1030.   Published online July 15, 1999
Isolated right ventricular hypoplasia, unassociated with severe pulmonary or tricuspid valvar malformations, is a rare primary congenital cardiac anomaly in which of the trabecular portion of right ventricle fails to develop. An atrial septal defect or a patent foramen ovale serves as an escape valve. We observed a 2-day-old neonate with this disorder who suffered from cyanosis. The diagnosis was...
Original Article
Correlation between Plasma Endothelin-1 Concentrations and Pulmonary Hypertension Associated with Congenital Heart Defects
Sang Ook Park, Su Eun Park, Hyang Jae Yoo, Young Tak Lim, Hee Ju Park
Clin Exp Pediatr. 1996;39(7):970-976.   Published online July 15, 1996
Purpose : Endothelin-1 is the most potent vasoconstrictor. This study was investigated the correlation of plasma endothelin-1 and pulmonary hypertension associated with congenital heart defect. Methods : We evaluated the concentration of ET-1 in 24 cases of congenital heart disease diagnosed at the Department of Pediatrics, Pusan National University, from December 1993 to September 1994. The patients were divided into 2 groups according to mean...
Case Report
A Case of Ring 14 Chromosome Syndrome
Jeong Hwa Choi, Han Sang Cho, Young Tak Lim, Hee Ju Park
Clin Exp Pediatr. 1995;38(11):1583-1587.   Published online November 15, 1995
A case of ring 14 chromosome syndrome, confirmed by chromosome study, was dis¡ⓒ cribed. She was 15 months old and manifestated facial abnormalities containing micro¡ⓒ cephaly, flat occiput, hyperterrorism and psychomotor retardation, intractable seizure. Chromosomal study showed the ring 14 chromosome, karyotypic ally she was depicted 46, XY, r(14). A brief review of all literature was also presented.
Original Article
Studies on Mechanism of Vascular Hyporeactivity of Mesenteric Artery from Septic Rats
Man Chul Ha, Hee Ju Park, Ki Whan Hong
Clin Exp Pediatr. 1995;38(7):922-935.   Published online July 15, 1995
Purpose : Septic shock due to gram negative bacterial infection is characterized by vasodil-ation, hypotension, and myocardial depression due to the effect of lipopolysaccharide (LPS). In spite of extensive studies, the mechanisms for the vascular effects of endotoxemia are not clear. Recently, it has been proposed that nitric oxide (NO) synthesized from L-arginine by nitric oxide synthase contributes to the...
Case Report
A Case of Eosinophilic Gastroenteritis in a Child
Young Don Kim, Jung Hwa Choi, Young Tak Lim, Hee Ju Park
Clin Exp Pediatr. 1995;38(4):552-556.   Published online April 15, 1995
Eosinophilic gastroenteritis is an uncommon disorder of the stomach, small bowel, and colon, characterized by eosinophilic infiltration of the gut wall and peripheral blood eosinophilia. The clinical features depend on the site of eosinophilic infiltration. Patients with eosinophilic gastroenteritis may develop an exudative ascites containing eosinophils. We experienced a case of eosinophilic gastroenteritis in a 9 year old boy who had...
G Deletion Syndrome II
Bon Su Koo, Sang Uk Park, Yung Tak Lim, Hee Ju Park
Clin Exp Pediatr. 1995;38(2):240-244.   Published online February 15, 1995
We experienced a case of G deletion syndrome II in a 8 year and 1 month old boy. He showed mental retardation, microcephaly, high arched palate, low set malformed ears, epicanthal fold, thoracic deformity, tracheomegaly and two lumens of esophagus. Chromosomal study showed the deletion of long arm of chromosome 22, kariotypically he was depicted as 46, XY, 22q-. A brief...
Congenital Adrenal Hyperplasia with 21-hydroxylase Deficiencies in Twins
Young Don Kim, Jeong Hwa Choi, Jae Hong Park, Hee Ju Park, Seong Suk Jeon
Clin Exp Pediatr. 1994;37(10):1469-1473.   Published online October 15, 1994
Congenital adrenal hperplasia is inherited disorder of adrenal steroidogenesis. 21-hydroxylase deficiency is the most commone enzymatic defect and is divided into classic and late-onset or nonclassic forms. Both classic and non-classic 21-hydroxylase deficiencies are inherited in a recessive manner as allelic variants. But it is rare that happened in twin infants. Chief complaints of affected twins in our case were ambiguous...
Original Article
A Clinical Study on Chronic Hepatitis b in the Children
Bon Su Koo, Han Sang Joo, Yung Tak Lim, Hee Ju Park
Clin Exp Pediatr. 1994;37(6):767-775.   Published online June 15, 1994
The author observed clinical study and response of -interferon treatment of 43 cases of chronic hepatitis who were admitted to Department of Pediatrics Pusan National University College of Medicine during the period of 4 year 6 months from Jenuary, 1988 to Jun, 1992. The results were as follows: 1) Of 43 patients with chronic hepatitis CPH was 17 cases (39.5%) and CAH...
Case Report
A Case of Ulcerative Colitis
Byung Mun Lee, Se Ook Oh, Se Chang Ham, Hee Ju Park, Hee Ju Park, Chan Tung Kim
Clin Exp Pediatr. 1992;35(9):1307-1313.   Published online September 15, 1992
The authors experienced a case of ulcerative colitis in a 15 year old girl. She was admitted to our department because of recurrent bloody mucous diarrhea, lower abdominal cramps and anorexia for 3 year. The diagnosis was established by clinical feature, radiological, endoscopic and histologic findings. The patient had an initial improvement after taking combined medication as sulfasalzine and prednisolone, followed...
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