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Review Article
Neonatology (Perinatology)
Update of minimally invasive surfactant therapy
Gyu-Hong Shim
Clin Exp Pediatr. 2017;60(9):273-281.   Published online September 21, 2017

To date, preterm infants with respiratory distress syndrome (RDS) after birth have been managed with a combination of endotracheal intubation, surfactant instillation, and mechanical ventilation. It is now recognized that noninvasive ventilation (NIV) such as nasal continuous positive airway pressure (CPAP) in preterm infants is a reasonable alternative to elective intubation after birth. Recently, a meta-analysis of large controlled trials...

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