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Editorial
Gastroenterology
Recent advances in epigenetic mechanisms, diagnosis, and treatment of pediatric gastrointestinal allergic disorders
Eell Ryoo
Clin Exp Pediatr. 2023;66(6):250-251.   Published online May 19, 2023
· Epigenetic mechanisms are involved in rapidly increasing food allergy.
· There is still no definitive way to diagnose food allergy.
· Early introduction of peanuts, eggs, and cow’s milk reduces food allergy incidence.
· Administration of probiotics such as Lactobacillus rhamnosus GG, Bifidobacterium bifidum can partially reduce the occurrence of allergic symptoms.
Review Article
Gastroenterology
Causes of acute gastroenteritis in Korean children between 2004 and 2019
Eell Ryoo
Clin Exp Pediatr. 2021;64(6):260-268.   Published online September 18, 2020
· Norovirus is the most common virus in Korean children with acute gastroenteritis.
· Escherichia coli and Salmonella spp. are the most common cause of bacterial gastroenteritis in Korean children, with a detection rate of 3%–20%.
· Uncommon bacterial and parasitic gastroenteritis require attention because of increasing international exchange and overseas travel.
Original Article
Allergy
Clostridium difficile colonization and/or infection during infancy and the risk of childhood allergic diseases
Sun Hwa Lee, Yun Na Gong, Eell Ryoo
Clin Exp Pediatr. 2017;60(5):145-150.   Published online May 31, 2017
Purpose

The gut microbiota can influence several diseases through immune modulation; however, the exact role of microbes such as Clostridium difficileand the relationship between microbiota colonization and allergic diseases are not well known. This study aimed to determine the relationship between C. difficilecolonization and/or infection (CDCI) during infancy and allergic diseases during early childhood.

Methods

Infants 1–12 months of age presenting changes in...

Gastroenterology
Risk factors of delayed diagnosis of acute appendicitis in children: for early detection of acute appendicitis
Jea Yeon Choi, Eell Ryoo, Jeong Hyun Jo, Tchah Hann, Seong Min Kim
Clin Exp Pediatr. 2016;59(9):368-373.   Published online September 21, 2016
Purpose

This study examined the risk factors of a delayed diagnosis of acute appendicitis in children undergoing an appendectomy.

Methods

This retrospective study involved children aged below 18 years, who underwent an appendectomy. After dividing them into a delayed diagnosis group and nondelayed diagnosis group according to the time interval between the initial hospital visit and final diagnosis, the risk factors of delayed...

Hepatitis associated with Mycoplasma pneumoniae infection in Korean children: a prospective study
Kyu Won Kim, Jae Jin Sung, Hann Tchah, Eell Ryoo, Hye Kyung Cho, Yong Han Sun, Kang Ho Cho, Dong Woo Son, In Sang Jeon, Yun Mi Kim
Clin Exp Pediatr. 2015;58(6):211-217.   Published online June 22, 2015
Purpose

Mycoplasma pneumoniae (MP) infection is a major cause of respiratory infection in school-aged children. Extrapulmonary manifestations of MP infection are common, but liver involvement has been rarely reported. The aim of this study was to determine the clinical characteristics of MP-associated hepatitis.

Methods

This prospective study included 1,044 pediatric patients with MP infection diagnosed serologically with MP IgM at one medical center...

Review Article
Adolescent nutrition: what do pediatricians do?
Eell Ryoo
Clin Exp Pediatr. 2011;54(7):287-291.   Published online July 31, 2011

Multiple psychosocial problems and many chronic diseases of adulthood can be influenced by adolescent nutritional problems. In Korea, adolescent obesity and obesity related health risks have been increased and insufficient intakes of nutrients, such as calcium, iron and potassium, and distorted thinking about obesity are also common. However there are no comprehensive countermeasure because of the excessive burden of studies...

Original Article
Current feeding practices and maternal nutritional knowledge on complementary feeding in Korea
Hye Won Yom, Jeong Wan Seo, Hyesook Park, Kwang Hae Choi, Ju Young Chang, Eell Ryoo, Hye Ran Yang, Jae Young Kim, Ji Hyun Seo, Yong Joo Kim, Kyung Rye Moon, Ki Soo Kang, Kie Young Park, Seong Soo Lee, Jeong Ok Shim
Clin Exp Pediatr. 2009;52(10):1090-1102.   Published online October 15, 2009
Purpose : To evaluate current feeding practices and maternal nutritional knowledge on complementary feeding. Methods:Mothers of babies aged 9-15 months who visited pediatric clinics of 14 general hospitals between September and December 2008 were asked to fill questionnaires. Data from 1,078 questionnaires were analyzed. Results : Complementary food was introduced at 4-7 months in 89% of babies. Home-made rice gruel was the...
Review Article
Recent concepts on vitamin D in children and adolescents
Hye Ran Yang, Jeong Wan Seo, Yong Joo Kim, Jae Young Kim, Eell Ryoo, Jae Geon Sim, Hye Won Yom, Ju Young Chang, Ji A Jung, Kwang Hae Choi
Clin Exp Pediatr. 2009;52(10):1082-1089.   Published online October 15, 2009
Vitamin D is an important fat-soluble vitamin that functions as a prohormone and affects bone mineralization and calcium homeostasis. Vitamin D deficiency causesboth musculoskeletal manifestations, including rickets, and extra-musculoskeletal symptoms. Because vitamin D is naturally present in only some foods, intake of daily foods cannot meet the dietary reference intake for vitamin D. Sunlight is the main source of vitamin...
Erratum
Assessment of modifiable lifestyle factors for obese children and adolescents through questionnaires
Jeong Wan Seo, Ji A Jung, Hye Sook Park, Jae Sung Ko, Yong Joo Kim, Jae Young Kim, Eell Ryoo, Sun Hwan Bae, Jae Geon Sim, Hye Ran Yang, Byung Ho Choe, Ky Young Cho
Clin Exp Pediatr. 2008;51(6):576-583.   Published online June 15, 2008
Purpose : The identification of specific behaviors conducive to overeating or inactivity is the cornerstone of obesity management. The Committee on Nutrition of the Korean Pediatric Society developed parent and self-reporting questionnaires about eating behavior and physical activity in 2006. The aim of this study was to evaluate the usefulness of the questionnaires in assessing modifiable lifestyle factors related to...
Original Article
Hepatitis Complicated with Mycoplasma pneumoniae Infection in Children
Seung Min Lee, Sung Moon Lee, Hann Tchah, In Sang Jeon, Eell Ryoo, Kang Ho Cho, Yong Han Seon, Dong Woo Son, Hee Joo Hong
Clin Exp Pediatr. 2005;48(8):832-838.   Published online August 15, 2005
Purpose : Mycoplasma pneumoniae infection is relatively common in childhood. Its extrapulmonary manifestations have been reported so much, but hepatitis associated with it has been reported rarely in Korea. Methods : A clinical study was performed on 556 patients of M. pneumoniae pneumonia diagnosed serologically at Gil hospital from January 2001 to December 2004. We reviewed 65 cases among these patients,...
Colon Perforation during Air Enema Reduction of Intussusception
Yong Kuk Kim, Hae Ra Im, Gwang Hoon Lee, Soo Jin Han, Yong Han Sun, Eell Ryoo, Kang Ho Cho, Hann Tchah, Hak Soo Lee
Clin Exp Pediatr. 2003;46(1):37-41.   Published online January 15, 2003
Purpose : Although air enema reduction has been known as a good method of diagnosis and treatment of intussusception, it could develop colon perforation. However, there have been few studies about this complication. So we analyzed the risk factors of colon perforation during air enema reduction in patients with intussusception. Methods : We reviewed the charts of 12 colon perforation patients...
Case Report
A Case of Saldino-Noonan Type Short Rib-Polydactyly Syndrome
Hye Young Han, Gwang Hoon Lee, Eell Ryoo, Kang Ho Cho, Mi Jin Jung, Gil Hyun Kim, Hak Soo Lee, Hyuni Cho
Clin Exp Pediatr. 2000;43(4):578-582.   Published online April 15, 2000
Short rib-polydactyly syndrome(SRPS) is a rare type of skeletal dysplasia characterized by short limb dysplasia, thoracic hypoplasia, polydactyly and multiple visceral anomalies. It is transmitted as a autosomal recessive trait. There have been 4 classic types of SRPS, of which Saldino-Noonan type is the most common, and is characterized by very narrow thorax, short limb, postaxial polydactyly, striking metaphyseal dysplasia...
A Case of Alagille Syndrome
Eun Kyung Hwang, Gwang Hoon Lee, Eell Ryoo, Kang Ho Cho, Gil Hyun Kim, Hak Soo Lee, Ji Hye Kim, Sung Hae Park, Hee Sup Kim
Clin Exp Pediatr. 1998;41(3):410-414.   Published online March 15, 1998
Alagille syndrome is characterized by chronic cholestasis, posterior embryotoxon, skeletal abnormalities, cardiovascular abnormalities, and a typical face with prominent forehead and pointed chin. Its histological feature includes paucity of interlobular bile ducts. We experienced a 49-day-old female infant presenting with frequent upper respiratory tract infection and persistent jaundice. She had a typical face and chronic cholestasis. Echocardiograms revealed peripheral pulmonary...
A Case of Chronic Recurrent Multifocal Osteomyelitis
Weon Young Lee, Eell Ryoo, Mi Jin Jeong, Kye Hwan Seol, Kil Hyen Kim, Hak Su Lee
Clin Exp Pediatr. 1996;39(5):732-737.   Published online May 15, 1996
Chronic recurrent multifocal osteomyelitis(CRMO) is an unusual inflammatory process involving multiple osseous sites. No causative agent can be consistently isolated from these lesions despite multiple biopsies and the affected child purses a clinical course of chronic remissions and exacerbations independent of antibiotic therapy. Biopsy of the lesions did not reveal any pathogens. Immunologic investigation revealed no abnormality common to the patient...
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