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Case Report
A Case of Childhood Acute Lymphoblastic Leukemia with Monosomy 20 and Parotid Gland Involvement
Hae Rim Kim, Seung Ah Hong, Byung Kyu Choe, Heung Sik Kim, Jung Sook Ha, Dong Seok Jeon, Yu Na Kang
Clin Exp Pediatr. 2004;47(12):1347-1350.   Published online December 15, 2004
Hypodiploidy exists in 3-15% of patients with childhood acute lymphoblastic leukemia(ALL) and is associated with a poor prognosis. Monosomy 7 and monosomy 20 account for most karyotypic abnormalities in patients in whom whole chromosomes are lost and their incidences are rare. Parotid tumors in the pediatric age group are unusual and in 1996, there was a case of invasion of...
Original Article
A Clinical Study of Children Who Showed Benign Hemophagocytic Histiocytes in Bone Marrow Examination
Jin A Park, Joo Young Park, Ji Min Park, Seat Byoul Park, Heung Sik Kim, Dong Seok Jeon
Clin Exp Pediatr. 2002;45(8):1007-1015.   Published online August 15, 2002
Purpose : The aim of this study is to find a method to diagnose and treat children who showed benign hemophagocytic histiocytes in bone marrow examination. Methods : We analyzed the clinical data of thirty patients retrospectively who showed benign hemophagocytic histiocytes in bone marrow examination from January 1995 to November 2001 at Keimyung University Dong-san Hospital. Bone marrow histiocytes...
Case Report
MRI Finding of a Case of Relapsed Acute Mixed Type Leukemia with Bone Marrow Necrosis
Joo Young Park, Euk Park, Seat Byeoul Park, Dong Seok Jeon, Hee Jung Lee, Heung Sik Kim, Chin Moo Kang
Clin Exp Pediatr. 2002;45(2):256-260.   Published online February 15, 2002
Bone marrow necrosis is a rare complication of a variety of diseases affecting the marrow. The cause and incidence are unknown, and reports of treatment response are rare. We describe a case of relapsed acute mixed type leukemia with bone marrow necrosis. The patient was a 10 year old female diagnosed with acute mixed type leukemia four years ago. She...
Original Article
Megakaryocyte Colony Formation of Fetal Liver Cells
Byung O Kwon, Hye Young Ju, Chun Soo Kim, Dong Seok Jeon, Jong In Kim, Heung Sik Kim
Clin Exp Pediatr. 2002;45(2):247-255.   Published online February 15, 2002
Purpose : This study was undertaken to obtain basic data about the megakaryocyte colony formation of fetal liver cells by using immunocytochemical staining and ex vivo culture with growth factors. Methods : The mononuclear cells were isolated from fetal liver and bone marrow with idiopathic thrombocytopenic purpura(ITP) and pancytopenia. These mononuclear cells were cultured in MegaCultTM-C(Stem Cell Tech, Canada) media in...
Urinary Red Cell Volume in the Diagnosis of Glomerular and Non-Glomerular Heaturia in children
Jong Sul Kwon, Dong Seok Kim, Myung Sung Kim, Joon Sik Kim, Chin Moo Kang, Dong Seok Jeon
Clin Exp Pediatr. 1994;37(1):40-46.   Published online January 15, 1994
Hematuria is a important clinical sign that is a consequence of significatn renal, urologic or sytemic disease. Recently the morphology of the red cell in hematuria has been used to indicate a renal or non-renal source and also the measurement of red cell volume by red cell analyzer has been used to distinguish glomerular from non-glomerular hematuria. In this study, the...
A case of acute megakaryoblastic leukemia with Down syndrome.
Sung Jin Chang, Sung Min Sohn, Heung Sik Kim, Chin Moo Kang, Dong Seok Jeon
Clin Exp Pediatr. 1991;34(12):1730-1735.   Published online December 31, 1991
We experienced a case of acute megakaryoblastic leukemia (M7) with Down syndrome. The patient was admitted due to premature SGA, which revealed characteristic facial figure of Down syndrome. M7 was diagnosed with PB smear which showed abundant megakaryoblast and confirmed by using the monoclonal antiplatelet glycoprotein IIb/IIIa antibody (J 15). On 25th hospital day, the patient gained weight but discharged without further treatment of M7. Authors...
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