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Allergy and Genetics
Dong Hak Shin
Clin Exp Pediatr. 1994;37(4):439-451.   Published online April 15, 1994
Allergy was originally defined in 1906 in 1906 by Clemens von Pirquet as 'altered reactivity' to denote the different reaction which occurs on second exposure to an antigen due to the formation of antibodies, when compared to the first exposure. The term atopy decribes the clinical presentation of Type I hypersensitivity, which include asthna, eczema, hay fever and urticaria....
Original Article
A Clinical Review of Congenital Gastrointestinal Anomalies
Dong Hak Shin, Woo Hyun Park, Chul Young Bae
Clin Exp Pediatr. 1993;36(7):944-950.   Published online July 15, 1993
A clinical review was done on 343 infants and children diagnosed and operated at the Department of Pediatric Surgery in Keimyung University, Dong San Medical Center for congenital gastrointestinal anomalies from January, 1988 to December, 1991. The results are summarized as follows; 1) The most prevalent age group of congenital gastrointestinal anomaly was within first week after birth, and infants within 3months...
A Role of Electrolytes in Fetal Tracheal Fluids As a Fetal Lung Maturity Profile.
Dong Hak Shin, Sung Do Yoon
Clin Exp Pediatr. 1988;31(10):1267-1274.   Published online October 31, 1988
The Fetal lung is filled by fluid from the beginning of the canalicular stage until the completion of fetal development. The fluid is produced by the lungs and flows out of the traches: Part of it is swallowed & part enters the amniotic fluid. The fluid is differs in composition from the plasma & amniotic fluid. Ifs electrolytes components change very little during...
Clinical and Epidemiological Studies on Childhood Bronchial Asthma.
Dong Hak shin
Clin Exp Pediatr. 1987;30(12):1368-1377.   Published online December 31, 1987
Chilhood bronchial asthma tends to be increased annually and overall incidence is about 3-10% of childhood age. Asthma is a troublesome disease during school life and nocturnal attacks often frighten the family. Asthma is a chronic obstructive pulmonary disease but usually self remmission with or without specific treatment. Asthma can be triggered by a variety of causative facotrs such as extrinsic, emotional, environmental,...
Hepatitis with Positive HBsAg in 3 Generations in 3 Families.
Dong Hak Shin
Clin Exp Pediatr. 1987;30(11):1265-1273.   Published online November 30, 1987
Since Jolly reported multiple occurences of cryptogenic cirrhosis in children in a family members in 1892, there had been sporadic cases reported and this familial liver cirrhosis was called as familial juvenile cirrhosis by Gunn. In 1960, numer of family pedigree of chronic liver diseases (such as chronic hepatitis, liver cirrhosis and liver cell carcinoma) in adult was more numerous than that of in...
The Influence of Hepatitis B Virus to Neonates.
Dong Hak Shin, Rac Kyun Ro, Sung Do Yoon
Clin Exp Pediatr. 1986;29(1):51-57.   Published online January 31, 1986
To evaluate the influence of HBV to fetus, authors studied 817 pregnant women and neonates who were admitted to delivery room of Keimyung University Dongsan medical center from 1882 to 1984. The results were as follows; 1) Percent of HBsAg positive mother was 6.8% (50/817) and child bearing age was 7.8% (72/917). Percent of Anti-HBs positive was 33.9% and...
Case Report
A Case of Congentital Leukemia.
Joon Sik Kim, Chang Ik Lee, Dong Hak Shin
Clin Exp Pediatr. 1984;27(8):802-807.   Published online August 31, 1984
Congenital leukemia is rare disease and several cases were reported in this country. We experienced a case of congenital leukemia(myelomonocytic type) in a 27 days old female. She was admitted due to marked abdominal distension, vomiting and generalized petechia. The diagnosis was established by clinical features as well as peripheral blood and bone marrow studies. We report this case with...
A Case of Primary Lung Cancer(Squamous cell ca) in Children.
Yong Ae Kim, So Kyung Park, Dong Hak Shin, Sang Suk Lee
Clin Exp Pediatr. 1984;27(2):178-183.   Published online February 28, 1984
This paper presented a case of primary lung cancer (squamous cell ca) in children, found a 12 years old boy. This patient was presented chief complaints of respiratory difficulty, procuctive cough and high fever. Diagnosis of lung cancer was made thuough bronchoschopic biopsy of bronchus with sputum cytology. We thought this is unusual case and we reviewed literatures and could not find the...
A Case of Osteogenesis Imperfecta Type II.
Chang Ick Lee, Young Ai Kim, Jung Joo Kim, Dong Hak Shin
Clin Exp Pediatr. 1984;27(1):93-97.   Published online January 31, 1984
Osteogenesis, imperfecta is an inherited disorder of connective tissue characterized by multiple fractures, blue sclerae, progressive deafness, loose jointedness, and skin. We experienced a case of Type I osteogenesis imperfecta in a 2 months old male infant who visited our hospital with chief complaints of generalized growth retardation, blue sclera and frequent fractures and deformities of limbs. With typical manifestation...
A Case of Neonatal Hyperthyroidism.
Gui Hee Jun, Yeon Sang Lee, Jung Ju Kim, Dong Hak Shin
Clin Exp Pediatr. 1983;26(9):939-944.   Published online September 30, 1983
The pathogenesis of neonatal hyperthyroidism has been known to be related with LATS,LATS-P, TSI and cell mediated immunity. The authors studied a case of neonatal hyperthyroidism born to a mother having a history of hyperthyroidism and diagnosed it through clinical symptoms of tremor, exophthalmos, tachycardia, excessive activity, nervousness and the thyroid function tests of T3, T4, RAI uptake and TSH. This case has...
A Case of Hand Schuller Christian Disease.
Yeon Saeng Lee, Soo Young Kim, So Kyung Park, Dong Hak Shin
Clin Exp Pediatr. 1983;26(4):392-396.   Published online April 30, 1983
Hand-Schuller-Christian disease is reactive granulomatous lesion with histiocytic proliferation, the cause of which is unknown. Recently, we experienced a case in a 3 years old female with polydipsia and polyuria. We established the diagnosis with clinical features, radiologic examination and bone biopsy- Histiologic examination of frontal bone showed mild to moderate infiltration of eosinophils, lymphocytes, plasma cells and large histioytes and fibrosis. Similiar cases reported in...
A Case of Chylous Ascites.
Sung Ho Chun, Yeon Sang Lee, Jung Ju Kim, Dong Hak Shin
Clin Exp Pediatr. 1982;25(12):1280-1284.   Published online December 31, 1982
A 4-months old male infant was admitted to the department of pediatrics because of abdominal distension, Inguinal hernia, Diarrhea and mild dyspnea. The clinical symptoms, sign and laboratory findings were compatible with chylous ascites. Clinical study and review of literature were made briefly.
Congenital Esophageal Atresia and Tracheoesophageal Fistula.
Kwang Woo Kim, Kyung Suk Choi, Jung Woo Kim, Dong Hak Shin, Seockil Zeon
Clin Exp Pediatr. 1982;25(11):1150-1154.   Published online November 30, 1982
We have experienced four cases of congenital esophageal atresia and tracheoesophageal ■fistula during the period of 3 years from Mar, 1979 to Sep. 1981, who were hospitalized at Dong San Hospital. The diagnosis was confirmed by esophagography, operation and autopsy. All four cases had upper blind pouch and lower tracheoesophageal fistula. Combined anomalities were aberrent subclavian artery, imperporated anus, estopic anus, hemivertebrae, polydactyly. Only one of four...
A case of perinephric abscess with perinephrobronchial fistula.
Ji Yoon Chung, Seung Woo Moon, So Kyung Park, Dong Hak Shin
Clin Exp Pediatr. 1982;25(9):963-966.   Published online September 30, 1982
Perinephric abscess is an accumulation of pus in the perinephric space, an area anatomically defined between kidney and Gerota’s fascia. The abscess is usually confined to an the anatomic boundaries of Gerota*s fascia but may extend in several directions. Rarely perinephrobronchial fistula may occur. We have experienced a case of right perinephic abscess with perinephrobronchial fistula in 2-year-old boy who had renal dysplasia and ureterocele on...
Original Article
HLA Type in Bronchial Asthma and Atopic Dermatitis.
Ji Yoon Chung, Myung Sook Kim, Jung Ju Kim, Dong Hak Shin
Clin Exp Pediatr. 1982;25(5):460-466.   Published online May 31, 1982
Since the histocompatibility was discovered, we have studied and determined many HLA types till the last workshop held in Los Angeles, USA, 1980. Nowadays we apply HLA types to organ transplantation, transfusion of blood, identification of paternity, study of ethnology and diagnosis of a specific disease. In the present study, 20 cases of bronchial asthma and 15 atopic dermatitis patients...
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