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Case Report
Four Cases of Staphylococcal Scalded Skin Syndrome
Chul Han Park, Yoo Jin Jeong, Won Jung Choi, Sat Byul Park, Heung Sik Kim, Chin Moo Kang
Clin Exp Pediatr. 2004;47(1):106-110.   Published online January 15, 2004
Staphylococcal scalded skin syndrome is a systemic disease with a clinical spectrum ranging from subcorneal pustules, patterned exfoliation to extensive erosion and peeling of skin by the exfoliative toxin of group II Staphylococcus aureus. This disease occurs mainly in infancy and children below five years and it isn't easy to differentiate from other vesicular diseases clinically, but skin biopsy shows...
Original Article
Endoscopic Findings of Children with Henoch-Schonlein Purpura
Dong Hoon Lee, Chul Han Park, Ji Min Park, Geun Soo Park, Heung Sik Kim, Chin Moo Kang
Clin Exp Pediatr. 2003;46(6):572-575.   Published online June 15, 2003
Purpose : This study was performed to analyze the endoscopic findings in Henoch-Schonlein purpura patients, and to compare the differences in endoscopic findings according to age and gastrointestinal symptoms. Methods : We examined children with Henoch-Schonlein purpura aged 3 to 15 years between September 1996 and October 2002. The total number studied was 65, consisting of 41 boys and 24...
Case Report
MRI Finding of a Case of Relapsed Acute Mixed Type Leukemia with Bone Marrow Necrosis
Joo Young Park, Euk Park, Seat Byeoul Park, Dong Seok Jeon, Hee Jung Lee, Heung Sik Kim, Chin Moo Kang
Clin Exp Pediatr. 2002;45(2):256-260.   Published online February 15, 2002
Bone marrow necrosis is a rare complication of a variety of diseases affecting the marrow. The cause and incidence are unknown, and reports of treatment response are rare. We describe a case of relapsed acute mixed type leukemia with bone marrow necrosis. The patient was a 10 year old female diagnosed with acute mixed type leukemia four years ago. She...
Original Article
Infectious Manifestations in Childhood Leukemia
Yoon Jung Cho, Heung Sik Kim, Chin Moo Kang
Clin Exp Pediatr. 2001;44(9):1019-1030.   Published online September 15, 2001
Purpose : Infection is one of the major causes of morbidity and mortality in children during chemotherapy for leukemia and the development of fever in neutropenic cancer patients frequently indicates infection. The purpose of the present study is to evaluate infectious manifestations during the course of leukemia. Methods : Seventy eight leukemic children who had one or more occasions of infection during hospitalization from January...
Case Report
A Case of Relapsed Acute Promyleocytic Leukemia Induced Remission with Arsenic Trioxide(As2O3)
Jin Hye Park, Heung Sik Kim, Chin Moo Kang
Clin Exp Pediatr. 2000;43(8):1132-1136.   Published online August 15, 2000
Acute promyelocytic leukemia(APL) is a unique entity in the spectrum of acute myelogenous leukemia. It has several characteristic features, including distinctive morphology, chromosomal translocation, t(15:17), disseminated intravascular coagulation and effect on retinoic acid. Retinoic acid which is a derivative of vitamin A induces differentation of APL cells in vitro and in vivo, but its cessation induces relapse of APL. Arsenic...
A Case of Acute Leukemia Remitted by Adding Cyclosporin-A Previously Failed with Induction Therapy
Seat Byeoul Park, Byung Kyu Choe, Heung Sik Kim, Chin Moo Kang
Clin Exp Pediatr. 2000;43(7):988-992.   Published online July 15, 2000
Clinical chemotherapy refractoriness is characterized by resistance to multiple drugs. Multidrug resistance(MDR) is caused by over-reactivity of a unidirectional drug efflux pump, transmembrane glycoprotein(P-glycoprotein), which is encoded by the MDR1 gene. P-glycoprotein leads to increased drug efflux and decreased intracellular drug concentration. Clinical trials that attempt to reverse or modulate MDR have been done. Cyclosporin-A and verapamil are the most extensively studied agents and several...
Original Article
Clinical Manifestation of Childhood Acute Leukemia with Bone Involvement
Kyoung Eun Jeong, Hee Jung Lee, Kwang Soon Song, Heung Sik Kim, Chin Moo Kang
Clin Exp Pediatr. 2000;43(6):806-813.   Published online June 15, 2000
Purpose : Bone involvement is known to develop in 40-70% of pediatric acute leukemia. We aimed to analyze the clinical course and result of therapy in pediatric acute leukemia with bone involvement. Methods : Twenty-seven patients diagnosed as pediatric acute leukemia at Dong San Medical Center from Jan. 1996 to Aug. 1998 were evaluated. According to bone X-ray and whole body...
Anticancer Effect of Arsenic Trioxide in Acute Promyelocytic Leukemia
Ki Young Song, Jin Hye Park, Yoon Jung Cho, Won Ki Baek, Ki Young Kwon, Heung Sik Kim, Chin Moo Kang
Clin Exp Pediatr. 2000;43(3):327-334.   Published online March 15, 2000
Purpose : Acute promyelocytic leukemia(APL or AML, M3) represents an unique model for cancer research in terms of biological and clinical features. Since 1988, it has been widely confirmed that all-trans retinoic acid(ATRA) can induce complete clinical remission in over 85% of APL patients by a differentiation process, with PML-RARα protein possibly being the direct target of ATRA. However, ATRA...
Erratum
Childhood Cancer and Infection
Chin Moo Kang
Clin Exp Pediatr. 2000;43(3):315-321.   Published online March 15, 2000
Original Article
Chemosensitivity Test of Childhood Leukemic Cells
Tae Woong Ha, Su Kyung Jung, Heung Sik Kim, Chin Moo Kang
Clin Exp Pediatr. 1999;42(8):1111-1121.   Published online August 15, 1999
Purpose : The purpose of the present study is to determine the relation between in vitro resistance to 9 drugs, measured with colorimetric methylthiazol tetrazolium(MTT) assay and prognostic factors. Methods : Thirty children with leukemia were evaluated at the pediatric department of Dongsan Medical Center. All samples tested with the MTT assay contained 80% or more leukemic cells, which were isolated...
Surgical Treatment for Intractable Childhood Epilepsy
Yoon Jung Cho, Chun Soo Kim, Joon Sik Kim, Chin Moo Kang, Ji Eun Kim, Sang Do Yi, Eun Ik Son
Clin Exp Pediatr. 1998;41(11):1565-1574.   Published online November 15, 1998
Diagnostic Value of Stable Microbubble Rating Test and Shake Test for the Early Detection of Respiratory Distress Syndrome in Prematurity
Sung Eun Lee, Sang Lak Lee, Chin Moo Kang
Clin Exp Pediatr. 1994;37(11):1500-1507.   Published online November 15, 1994
Respiratory distress syndrome (RDS) of newborn is a disease revealed high morbidity and mortality rate, especially in premature infant. To evaluate the predictive value of Stable Microbubble Rating (SMR) and Shake test on RDS in premature infant, the anthors carried out the gastric aspirates Shake test and SMR test at birth, 3 and 6 hours after birth respectively on 124 premature...
Urinary Red Cell Volume in the Diagnosis of Glomerular and Non-Glomerular Heaturia in children
Jong Sul Kwon, Dong Seok Kim, Myung Sung Kim, Joon Sik Kim, Chin Moo Kang, Dong Seok Jeon
Clin Exp Pediatr. 1994;37(1):40-46.   Published online January 15, 1994
Hematuria is a important clinical sign that is a consequence of significatn renal, urologic or sytemic disease. Recently the morphology of the red cell in hematuria has been used to indicate a renal or non-renal source and also the measurement of red cell volume by red cell analyzer has been used to distinguish glomerular from non-glomerular hematuria. In this study, the...
Case Report
Two Cases of Gaucher's Disease in Brothers
Seung Beum Cho, Heung Sik Kim, Chin Moo Kang
Clin Exp Pediatr. 1993;36(12):1752-1760.   Published online December 15, 1993
We experienced two cases of Gaucher's disease of adult type in brother aged four years and two years. The patients showed hepatosplenomegaly with anemia and thrombocytopenia. Typical Gaucher cells were found in bone marrow and biopsy specimens of liver and spleen through light and electron microscopic examination. Splenectomy was followed by improvement of anemia and thrombocytopenia. A brief review of...
Original Article
Clincal Study on 12 Cases of Neonatal Group B β-Hemolytic Streptococcal Meningitis
Won Jin Kim, Sang Woog Lee, Sang Lak Lee, Myung Sung Kim, Chin Moo Kang
Clin Exp Pediatr. 1993;36(11):1507-1515.   Published online November 15, 1993
A clinical study was made on 12 cases of neonatal Group Bβ-hemolytic streptococcal(=GBS)meningitis, who were admitted to the department of Pediatrics, Dong-San Hospital, Keimyung University during the period of 3 years from Aug 1989 to Jul 1992. The following results were obtained 1) GBS was cultured in 12 cases(57.1%) among 21 neonatal meningitis admitted during the same period. 2) Male and female ratio...
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