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Review Article

Mechanisms of immune tolerance to allergens in children

Umut C. Kucuksezer, Cevdet Ozdemir, Mübeccel Akdis, Cezmi A. Akdis

Clin Exp Pediatr. 2013;56(12):505-513. Published online December 20, 2013

Because the prevalence of allergic diseases has significantly increased in recent years, understanding the causes and mechanisms of these disorders is of high importance, and intense investigations are ongoing. Current knowledge pinpoints immune tolerance mechanisms as indispensable for healthy immune response to allergens in daily life. It is evident that development and maintenance of allergens-pecific T cell tolerance is of...

DOI: https://doi.org/10.3345/kjp.2013.56.12.505

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