X-linked agammaglobulinemia (XLA) is a hereditary humoral immunodeficiency that results from Bruton’s tyrosine kinase ( |
Recently, an increase in the number of patients sensitized to rice allergen with or without clinical symptoms has been reported. This study was designed to determine the major allergens in rice and their clinical significance. Twenty-four children (15 boys and 9 girls; mean age, 16.3 months) with allergic disease, who were sensitized to rice antigen (by UniCAP) in the Pediatric Allergy... |
Many patients assume that allergic reactions against foods are responsible for triggering or worsening their allergic symptoms. Therefore, it is important to identify patients who would benefit from an elimination diet, while avoiding unnecessary dietary restrictions. The diagnosis of food allergy depends on the thorough review of the patients's medical history, results of supplemented trials of dietary elimination, and in... |
Purpose : We aimed to evaluate the frequency and characteristics of minor clinical manifestations of atopic dermatitis (AD) in Korean children to aid the diagnosis and treatment of AD. Methods : From April 2007 to December 2007, we enrolled 106 children (aged 1 month [infants] to 15 years) diagnosed with AD at the Pediatric Allergy Respiratory Center in Soonchunhyang University Hospital.... |
Purpose : It is widely known that allergic diseases progress through an allergic march. However, there have not been any recent reports in Korea on how the diseases progress. Methods : Parents who visited one of the Pediatric Allergy Clinics of four university hospitals in Seoul with a child under the age of 6 years during the period from May... |
Purpose : The results of pulmonary function test (PFT) in children are variable according to the patient's cooperation and comprehensiveness. This study has intended to figure out the effectiveness of pre-education and training with balloons on PFT in children. Methods : One hundred six children mean aged 9.35?.92 years were tested. All participants performed PFT twice in 30 minutes intervals.... |
Purpose : Theophylline has recently been reported to have concurrent anti-inflammatory effects at low therapeutic plasma concentrations which are below the doses at which significants, clinically useful bronchodilatation is evident. Sustained-release formulation in capsule and dry syrup forms were developed to reduce its adverse effects and improve its clinical effects. We compared the therapeutic effects of theophylline dry syrup and... |
Atopic dermatitis is estimated to affect 15-20% of the childhood population and there id considerable evidence that the prevalence is increasing. But it is frequently under diagnosed and inappropriately treated yet. Atopic dermatitis can have a large social;. emotional and financial effect on the child and their family. Atopic dermatitis also commonly predated the development of asthma and allergic rhinitis.... |
Purpose : Outbreaks of mumps continue to occur, even though the number of patients diagnosed of mumps has decreased considerably with the widespread use of vaccine. The accurate diagnosis of mumps is needed to understand the epidemiology of mumps and analyse the safety and effectiveness of vaccine. Therefore, we attempted to appraise the accuracy of provisional diagnosis of mumps in... |
Purpose : This prospective study was performed to evaluate the immunogenecity and safety of MMR vaccine(Triviraten Berna¢c) in Korea children. Methods : Seventy-three infants aged between 12 to 18 months were recruited from several university hospitals between December 1995 to June 1996. MMR vaccine(Triviraten Berna¢c) was administrered and blood was obtained before and 6-10 weeks after vaccination. IgG antibodies against measles,... |
Purpose : Although the chronic sinusitis is one of the most common and troublesome respiratory diseases in children, the pathogenesis still remains unclear. It is suggested that many of the immunologic factors including allergic conditions may contribute the nasal inflammatory changes. This study was designed to evaluate and demonstrate the possible role of various immunologic factors on the pathogenesis of... |
Recently many studies and development of allergology especially in allergic rhinitis have been carried out and the number of allergic rhinitis patients has been increased. In order to get basic clinical information, the authors performed clinical and diagnostic analysis with 132 cases complaining of nasal stuffness, watery rhinorrhea or sneezing who visited the out- patient department of Pediatrics, Soon Chun Hyang University Hospital from... |
Presently, an increasing incidence of Bronchial asthma in children is of concern to medical professionals. Worldwide data from surveys indicate a wide range for the prevalence of childhood asthma, it has been estimated that 5-10% of the young population. An epidemiological approach was used to test the prevalence of bronchial asthma out of all pediatric cases referred to the emergency room. 248 cases were selected... |
We observed a case of congenital nonspherocytic hemolytic anemia who was a 24 month old boy with the signs of jaundice 技 pallor. Evidences of the same disease was also found in the patient' s elder brother & father. We diagnosed these cases by history & physical examination, peripheral & B.M. blood smears, osmotic fragility test, autohemolysis test and etc. A... |
A Condition characterized Ijy a generalized malignant proliferation of the nucleated red blood cells resembling leukemia was first recognized as a clinical and pathological entity by Di Guglielmo in 1923. We experienced a case of erythroleukemia, who had suffered from abdominal distension for 5 month and multiple ecchymosis on lower extremities. Peripheral blood smear and bone marrow examination revealed proliferation... |
We have observed clinically about 161 cases of anemia among 251 patients who were admitted to Y.D.P.C.H. The results were obtained as follows: 1)The incidence of anemia among total admitted patients (251) was 64.1% (161 cases). These were grouped into mild & moderate anemia(58.2%) and severe anemia (5.9%) on the base of hemoglobin level. 2)The sex ratio was aproximatly 1.5 : 1... |
A case of lacunar skull associated with meningomyelocele, spina bifida, kyphcsis on thoracolumbar area, hydrocephalus, bilateral club foot and paralysis of lower extremities at birth was reported. Diagnosis was made by X-ray of skull, whole spine, upper and lower extremities. On skull X-ray film, multiple small area of round rarefaction surrounded by arborizing pattern of bony ridge was visualized on... |
Kawasaki Disease of Mucocutaneous Lymph Node Syndrome, first described by Kawasaki in 1967, is an acute febrile disease of unknown etiology. Until recently, more than 17,000 cases of this disease have been listed in the survey of a special study group supported by the Japanese Ministry of Health and Welfare. And a number of cases have been reported even outside... |