Clinical and Experimental Pediatrics

Original Article

Clinical Characteristics of Recurrent Kawasaki Disease

Hyun Ji Lee, Ae Ra Cho, Hae Soon Kim, Sejung Sohn

Clin Exp Pediatr. 2004;47(8):879-883. Published online August 15, 2004

Purpose : The purpose of this study is to investigate the clinical manifestations and the risk factors of recurrent Kawasaki disease(KD). Methods : From March 1995 to June 2003, 14 children with recurrent KD in Ewha Womans University Hospital were retrospectively evaluated by reviewing their admission reports. The clinical characteristics, laboratory findings, treatment and complications of the recurrent KD group were...

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Matrix Metalloproteinases, Tissue Inhibitors and Cytokines in Patients with Kawasaki Disease

Ae Ra Cho, Young Mi Hong

Clin Exp Pediatr. 2004;47(6):656-664. Published online June 15, 2004

Purpose : Kawasaki disease(KD) is a multisystemic inflammatory vasculitis of unknown etiology, but immunological abnormalities have been documented and implicated in the pathogenesis of KD. Matrix metalloproteinases(MMPs) have proteolytic activity against connective tissue proteins, and increased activity of MMPs and a quantitative imbalance between MMP and tissue inhibitor of MMP (TIMP) can result in several pathologic conditions. MMP and TIMP...

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Aseptic Meningitis Secondary to High-Dose Intravenous Immunoglobulin Therapy in Kawasaki Disease

Ae Ra Cho, Jee Yoon Park, Kyung Hyo Kim, Young Mi Hong

Clin Exp Pediatr. 2004;47(5):561-566. Published online May 15, 2004

Purpose : Kawasaki disease is a multisystemic inflammatory vasculitis and associated with neurologic features such as aseptic meningitis. High-dose intravenous immunoglobulin(IVIG) is used to treat Kawasaki disease and generally considered to be safe, but rare cases of aseptic meningitis with unknown etiology have been reported. The aseptic meningitis associated with Kawasaki disease was compared with meningitis as the adverse reaction...

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