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Case Report
Necrotizing fasciitis and streptococcal toxic shock syndrome secondary to varicella in a healthy child
Byung Ok Kwak, Min Jung Lee, Hye Won Park, Min Kyung Song, Sochung Chung, Kyo Sun Kim
Clin Exp Pediatr. 2014;57(12):538-541.   Published online December 31, 2014

Varicella is usually considered to be a benign disease in healthy children; however, serious complications can occur such as necrotizing fasciitis and toxic shock syndrome. We describe a 38-month-old girl with necrotizing fasciitis and streptococcal toxic shock syndrome following varicella. She was previously healthy and vaccinated against varicella at 12 months of age. She had been diagnosed with varicella three...

Review Article
Emergence of macrolide resistance and clinical use of macrolide antimicrobials in children
Eun Hwa Choi
Clin Exp Pediatr. 2008;51(10):1031-1037.   Published online October 15, 2008
Macrolide antimicrobial agents including erythromycin, roxithromycin, clarithromycin, and azithromycin are commonly used in the treatment of respiratory tract infections in children. Newer macrolides that have structural modifications of older drug erythromycin show improved change in the spectrum of activity, dosing, and administration. However, recent studies reported that increasing use of macrolide antibiotics is the main force driving the development of...
Case Report
A Case of Streptococcal Toxic Shock Like Syndrome with Pleural Effusion
Jinyoung Song, Keunha Ji, Heeseuk Kim, Jungwoo Rhoo, Dongwook Kim, Jongkook Lee
Clin Exp Pediatr. 2001;44(2):200-204.   Published online February 15, 2001
Streptococcal toxic shock like syndrome is a rapidly progressive and a fatal disease like staphylococcal toxic shock syndrome. In spite of the wide expansion and development of potent antibiotics, streptococcal infection still threatens human being. Recently we experienced a patient with toxic shock like syndrome who was suffered from fever and neck pain with rapid progression to hypotension and multiorgan...
Original Article
Molecular Epidemiologic Study of Streptococcus pyogenes Analyzed by T protein Serotyping and Pulsed Field Gel Electrophoresis(PFGE) in Normal Children
Jin Ah Son, Don Hee Ahn, Kyu Jam Hwang, Younghee Lee, Sung-Ho Cha
Clin Exp Pediatr. 2000;43(10):1330-1342.   Published online October 15, 2000
Purpose : In this study we tried to look at the spreading, duration of colonization, and acquisition of new streptococci which were obtained in one geographical area, as well as the bacteriologic and molecular epidemiology of normal school children carrying group A streptococci and their clonal relationship through the combined application of the serotype of T antigen and Pulsed Field...
Epidemiologic Characteristics of T Serotyping in Relation to the Outbreak of Erythromycin Resistant Streptococcus pyogenes
Sung-Ho Cha, Kyu Jam Hwang, Young Hee Lee
Clin Exp Pediatr. 2000;43(10):1323-1329.   Published online October 15, 2000
Purpose : The identification of antigenic specificity of Streptococcus pyogenes using T serotyping is important to understand biologic characteristics of microorganisms. We would like to disover the association of the occurrence of predominant T type, with possible outbreak of erythromycin resistant Streptococcus pyogenes in this country, which has been documented since the late 1990s. Methods : Throat swab cultures were taken...
Bacteriological Survey of beta-Hemolytic Streptococci from the Throats of Elementary School Children in Chinju -Compared with the Results of Children in Kangwon, Chungnam and Seoul-
Seon-Ju Kim, Kook-Young Maeng, Hyang-Im Lee, Yun-Kyong Cho, Hee-Sang Yun
Clin Exp Pediatr. 1996;39(2):238-245.   Published online February 15, 1996
Purpose : Throat culture for streptococcal pharyngitis is a gold standard to diagnose, but it may be misleading to interpret due to the carriers. The isolation rates of beta-hemolytic streptococci (BHS) and Streptococcus pyogenes in the school children in Chinju were investigated and compared with those of Kangwon, Chungnam and Seoul previously reported. Methods : Throat cultures were taken from the...
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