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Purpose : Sex hormone binding globulin(SHBG) is produced in liver and binds to testostero-ne and estradiol. Plasma SHBG levels are increased by estrogen and thyrotoxicosis and decreased by testostrone, insulin, growth hormone, prolactin, obesity and noninsulin dependent diabetes mellitus.
SHBG levels in patients with NIDDM is known to be higher than normal, but SHBG levels in children with IDDM is controversial.... |
