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Review Article
Neurology
Worldwide national intervention of developmental screening programs in infant and early childhood
Seunghyo Kim
Clin Exp Pediatr. 2022;65(1):10-20.   Published online September 30, 2021
∙ Prevalence rate of developmental disabilities has been reported from 8% to 15% and its rate is increasing worldwide.
∙ The critical period of intervention for developmental delay is before the child reaches 3 years of age.
∙ All primary care pediatricians should conduct developmental surveillance and screening tests to infants and children at scheduled visits. Through this, they are liable for providing early identification and timely intervention.
Original Article
Developmental and Behavioral Medicine
Development of the Korean Developmental Screening Test for Infants and Children (K-DST)
Hee Jung Chung, Donghwa Yang, Gun-Ha Kim, Sung Koo Kim, Seoung Woo Kim, Young Key Kim, Young Ah Kim, Joon Sik Kim, Jin Kyung Kim, Cheongtag Kim, In-Kyung Sung, Son Moon Shin, Kyung Ja Oh, Hee-Jeong Yoo, Hee Joon Yu, Seoung-Joon Lim, Jeehun Lee, Hae-Ik Jeong, Jieun Choi, Jeong-Yi Kwon, Baik-Lin Eun
Clin Exp Pediatr. 2020;63(11):438-446.   Published online May 14, 2020
Question: Can the Korean Developmental Screening Test for Infants and Children (K-DST) be a useful screening tool for infants and children in Korea?
Finding: The K-DST has high reliability (internal consistency of 0.73–0.93, test-retest reliability of 0.77–0.88) and a high discriminatory ability with a sensitivity of 0.833 and specificity of 0.979.
Meaning: The K-DST is an effective and reliable screening tool for infants and children with neurodevelopmental disorders in Korea.
Validity of the Korean Developmental Screening Test for very-low-birth-weight infants
Chae Young Kim, Euiseok Jung, Byong Sop Lee, Ki-Soo Kim, Ellen Ai-Rhan Kim
Clin Exp Pediatr. 2019;62(5):187-192.   Published online March 20, 2019

Purpose: The importance of the neurodevelopmental outcomes of very-low-birth-weight (VLBW) infants has been emphasized as their mortality rate has markedly improved. This study aimed to assess the validity of the Korean Developmental Screening Test (K-DST), a developmental screening tool approved by the Korean Society of Pediatrics, for the timely diagnosis of neurodevelopmental delay in VLBW infants. Methods: Subjects included VLBW infants...
Usefulness of the Korean Developmental Screening Test for infants and children for the evaluation of developmental delay in Korean infants and children: a single-center study
Chung-Hyuk Yim, Gun-Ha Kim, Baik-Lin Eun
Clin Exp Pediatr. 2017;60(10):312-319.   Published online October 20, 2017
Purpose

To evaluate the usefulness of the Korean Developmental Screening Test (K-DST) for infants and children for developmental delay assessment.

Methods

This study was based on retrospective studies of the results of the K-DST, Preschool Receptive-Expressive Language Scale (PRES), Sequenced Language Scale for Infants (SELSI), Childhood Autism Rating Scale (CARS), Modified Checklist for Autism in Toddlers (M-CHAT), electroencephalography, magnetic resonance imaging, and extensive...

Neurology
Single-center experience of the Korean-Developmental Screening Test for infants and children
Chae-Ri Suh, Su Ye Sohn, Gun-Ha Kim, Seong-Kwan Jung, Baik-Lin Eun
Clin Exp Pediatr. 2016;59(12):483-489.   Published online December 31, 2016
Purpose

We investigated the number of test takers of the Korean-Developmental Screening Test (K-DST) in a single children's hospital within a year, according to age, referral rate, and follow-up percentage.

Methods

For this study, 4,062 children who visited and received K-DST at Woorisoa Children's Hospital between January and December 2015 were enrolled. Seven test sets were used according to the Korean National Health...

Spectrum of patients with hypermethioninemia based on neonatal screening tests over 14 years
Se Jung Oh, Yong Hee Hong, Yong Wha Lee, Dong Hwan Lee
Clin Exp Pediatr. 2010;53(3):329-334.   Published online March 15, 2010
Purpose : The neonatal screening test for homocystinuria primarily measures methionine by using a dried blood specimen. We investigated the incidence and clinical manifestations of homocystinuria, isolated hypermethioninemia, and transient hypermethioninemia among patients with hypermethioninemia on a neonatal screening test. Methods : We performed a retrospective study of 58 patients transferred to Shoonchunhyang Hospital because of hypermethioninemia on a neonatal...
The impact of early detection through school urinary screening tests of membranoproliferative glomerulonephritis typeⅠ
Sung-Hoon Chung, Sung-Sin Park, Sung-Do Kim, Byoung-Soo Cho
Clin Exp Pediatr. 2007;50(11):1104-1109.   Published online November 15, 2007
Purpose : Since 1998, school urinary screening tests have been performed on Korean school children. We could detect and treat so many asymptomatic chronic renal disease in early stage. We investigated the efficacy of school urinary screening tests from children with membranoproliferative glomerulonephritis (MPGN) type I. Methods : We analyzed the characteristics and prognosis of 18 patients with MPGN type I...
Analysis of newborn hearing screening using automated auditory brainstem response
Sung Won Park, Byung Ho Yun, Kyung Ah Kim, Sun Young Ko, Yeon Kyung Lee, Son Moon Shin, Sung Hwa Hong
Clin Exp Pediatr. 2006;49(10):1056-1060.   Published online October 15, 2006
Purpose : As hearing ability affects language and cognitive development, early detection and intervention of congenital hearing defects is very important. We analyzed the result of newborn hearing screening using automated auditory brainstem response and estimated the incidence of congenital hearing defects in newborn infants in Korea. Methods : Hearing screening tests were done on 7,218 newborn infants who were...
Usefulness of Korean Infant Developmental Screening Test in Premature Infants
Dong Han Shin, Hee Sun Lee, Jee Yeon Lee, Byung Min Choi, Baik-Lin Eun, Young Sook Hong, Joo Won Lee
Clin Exp Pediatr. 2005;48(12):1337-1341.   Published online December 15, 2005
Purpose : This study aimed to evaluate the usefulness of Korean Infant Development Screening Test in predicting delayed development in premature infants. Methods : A total of 74 children with histories of prematurity, who visited the pediatric neurology clinic of Korean University Ansan Hospital from August, 2002 to July, 2004, were examined, using the Korean Infant Development Screening Test. They were...
Investigation of Automated Neonatal Hearing Screening for Early Detection of Childhood Hearing Impairment
Jeong Il Seo, Si Uk Yoo, Sung Hyeon Gong, Kwang Su Hwang, Hyeon Jung Lee, Joong Pyo Kim, Hyeon Choi, Bo Young Lee, Ji Sun Mok
Clin Exp Pediatr. 2005;48(7):706-710.   Published online July 15, 2005
Purpose : Early diagnosis of congenital hearing loss through the neonatal hearing screening test minimizes language defect. This research intends to identify frequency of congenital hearing loss in infants through neonatal hearing screening test with the aim of communicating the importance of hearing test for infants. Methods : From May 20, 2003 to May 19, 2004, infants were subjected to Automated...
Reevaluation of the Neonatal Screening Test for Congenital Hypothyroidism
So Young Kang, Young Pyo Chang, Jeesuk Yu
Clin Exp Pediatr. 2005;48(4):387-394.   Published online April 15, 2005
Purpose : We performed this study to compare the TSH and free T4 levels according to gestational age and birth weight, and to reevaluate the cut-off values in the neonatal screening test for congenital hypothyroidism. Methods : Total 2,133 neonates(1,749 healthy newborns and 384 sick neonates) were screened in Dankook University Hospital from May 2000 to January 2003. Neonates with abnormal...
Clinical Lecture
Clinical Approach to the Children with Coagulation Deficiencies
Sang Kyu Park
Clin Exp Pediatr. 2004;47(10):1036-1040.   Published online October 15, 2004
This review deals with the coagulation deficiencies which are due to the abnormality in one of three hemostatic systems. It explains about the diagnostic examinations that should be done to differentiate for patients with bleeding tendency and the things to consider when preoperative screening tests for coagulation are abnormal.
Original Article
Screening Test for Heart Diseases in the First Grade Elementary School Children in Busan
Jae Min Oh, Hee Ju Park
Clin Exp Pediatr. 2003;46(5):490-494.   Published online May 15, 2003
Purpose : We'd like to determine the incidence of congenital heart disease and arrhythmia in elementary school children in Busan, and to provide adequate prevention and treatment. Methods : A total of 23,802(male 12,909, female 10,893) 1st grade elementary school children living in Busan were studied. All children were 7-8 years old. We obtained their medical history by questionnaire and checked...
The Ewha Infant Develomental Screening Test
Keun Lee
Clin Exp Pediatr. 2002;45(6):700-711.   Published online June 15, 2002
Purpose : Early identification and treatment of developmental disabilities is of considerable importance in the health care of children. Screening of development is aimed at identifying infants who may need more comprehensive evaluations. Methods : A new test, the Ewha Infant Development Screening Test(EDST) has been created to screen the development of infants, 0-4 years of age. EDST was constructed so...
Nitroblue Tetrazolium(NBT) Test as a Screening Test of Urinary Tract Infection in Children
Nyun Huh, Chang Hee Oh, Je Woo Kim, Phil Soo Oh, Hae Sun Yoon, Won Keun Song
Clin Exp Pediatr. 2001;44(10):1157-1161.   Published online October 15, 2001
Purpose : It has been reported that the Nitroblue Tetrazolium(NBT) test is more accurate than the urine pH, leukocyte esterase and nitrite test as a screening test of urinary tract infection (UTI). The purpose of this study is to compare the NBT test with other screening tests and evaluate the clinical usefulness of the NBT test as a screening test. Methods...
The Seoul Infant Developmental Screening Test
Keun Lee
Clin Exp Pediatr. 2000;43(3):335-343.   Published online March 15, 2000
Purpose : The importance of early detection of developmental delays during infancy and preschool years has been repeatedly stressed, as early diagnosis of retardation increases the opportunities for effective therapy. Several screening tests developed in other countries are inappropriate for Korean children. The purpose of this study was to standardize a developmental screening method for Korean children. Methods : One hundred...
Re-Evaluation of Neonatal Screening Tests for Inborn Errors of Metabolism with Dried Filter Paper Blood Spots
Kye Shik Shim, Jin Soon Hwang, Jung Sub Lim, Se Young Kim, Choong Ho Shin, Sei Won Yang, Jung Hwan Choi, Chong Ku Yun, Jung-Han Song
Clin Exp Pediatr. 1999;42(12):1639-1644.   Published online December 15, 1999
Purpose : There have been high rates of false positive and recall in neonatal screening test using the cut-off points set by the manufacturing company. So, it is necessary to re-evaluate the cut off values to minimize the false positive rates. Methods : We collected capillary blood in dry filter paper from 996 healthy neonates on the third day in cases...
Follow up of Infants with Congenital Hypothyroidism Who were Detected by Newborn Screening Test
Kyung Ah Kim, Eun Sil Lee, Son Moon Shin, Han Ku Moon, Yong Hoon Park
Clin Exp Pediatr. 1999;42(8):1141-1148.   Published online August 15, 1999
Purpose : Developmental delay in congenital hypothyroidism can be prevented by early detection and treatment. We conducted a follow-up study to assess the growth and development of infants with congenital hypothyroidism who were detected by newborn screening test and received thyroid hormone therapy. Methods : Nineteen hypothyroid infants were detected by newborn screening test from April 1995 to May 1997. Measurements...
Auditory Brainstem Responses in Premature and Fullterm Infants
Hyun Mi Kim, Tae Sung Ko, Ki Soo Kim, Moo Song Lee, Kyung Hee Kim
Clin Exp Pediatr. 1995;38(8):1036-1045.   Published online August 15, 1995
Purpose : We tried to know normal range of auditory brainstem responses in premature and fullterm infants who have no rksk factor during perinatal period and to determine that the abnormal ABR in premature and fullterm infants may predict developmental delay. Methods : ABR evaluations were performed on 283 premature and fullterm infants from NICU of the Asan Medical Center during...
Etiological Classification of Mentally Retarded Children Enrolled in a Special Educational Institution
Seon-Kyeong Yoo, Han-Wook Yoo
Clin Exp Pediatr. 1994;37(10):1437-1448.   Published online October 15, 1994
Mental retardation(MR) is classically deficits in adaptive behavior and manifest during the developmental period. The causes of mental retardation were not understood in many cases. This study was undertaken to identify the etiologies of mentally retarded children enrolled in a special educational institution under the hypothesis that clarifying causes of MR can not only provide basic epidemiological data on MR in...
Seventeen Years Experience on Inborn Errors of Metabolism A Study for Future Development of Inborn Errors of Metabolism in Korea.
Hong Jin Lee, Hyung Ro Moon
Clin Exp Pediatr. 1990;33(8):1031-1036.   Published online August 31, 1990
In Korea, the study of inborn errors of metabolism is very primitive. Even the incidence and prevalence of the disease of inborn errors of metabolism are not known in Korea. We have done this study of inborn errors of metabolism in Korea and concluded that: 1) The varieties and incidences of inborn errors of metabolism in Korea might be relatively diverse and high. 2) Nation wide mandatory...
Standardization of the Denver Developmental Screening Test on Seoul Children.
Kun Lee
Clin Exp Pediatr. 1987;30(9):958-971.   Published online September 30, 1987
Total 2140 Seoul children, aged from 2 weeks to 6 years 4 months were evaluated with Denver Developmental Screening Test and the results were compared with those of Denver and Tokyo children. Seoul children were found to be advanced in all 4 sectors of DDST, e.g. personal, social, fine motor, adaptvie, language and gross motor than Denver or Tokyo counterparts. Korean youngsters fast development...
Study on the Korean Infant Development Screening Test.
Jong Lin Rhi, Jung Hwan Choi, Hyung Ro Moon, Sechin Cho
Clin Exp Pediatr. 1987;30(8):852-867.   Published online August 31, 1987
Developmental problems are relatively prevalent and often treatable if early interventions are to be given. Much better prognosis will also be given if they are treated early & properly by early detection through the use of the developmental screening test. Developmental screening is the application of relatively quick and simple procedures to an asymptomatic population to select out those individuals who are highly likely...
Hematuria and Proteinuria in School Children.
Woon Sik Kim
Clin Exp Pediatr. 1981;24(1):13-23.   Published online January 15, 1981
The following results were obtained through the screening survey to detect the prevalence of hematuria & proteinuria in the healthy Korean schoolchildren. A total of 2,888 primary schoolchildren in Seoul, examined to be healthy by the author were tested for hematuria and proteinuria during the period of 3 months from Apr. 1979 to June 1979. Hemacombistix of Ames Company, U.S.A....
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