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Review Article
Neonatology (Perinatology)
Retinopathy of prematurity: a review of epidemiology and current treatment strategies
Eun Hee Hong, Yong Un Shin, Heeyoon Cho
Clin Exp Pediatr. 2022;65(3):115-126.   Published online October 12, 2021
There have been global tri-phasic epidemic periods of retinopathy of prematurity (ROP). In recent years, its incidence has reportedly been 10%–40% depending on country and study population. Current treatment strategies for ROP include laser photocoagulation, surgical treatment, and anti-vascular endothelial growth factor treatment, the role of which has drawn attention in recent years.
Original Article
Postnatal weight gain in the first two weeks as a predicting factor of severe retinopathy of prematurity requiring treatment
Jongmoon Kim, Jang Yong Jin, Sung Shin Kim
Clin Exp Pediatr. 2015;58(2):52-59.   Published online February 28, 2015

This study aimed to investigate the relative weight gain at 2-week intervals up to 6 weeks after birth to predict retinopathy of prematurity (ROP) requiring treatment among very low birth weight infants.


A total of 211 preterm infants with birth weights <1,500 g and gestational age <32 weeks were retrospectively reviewed. The main outcome was the development of ROP requiring treatment....

The outcomes of retinopathy of prematurity in relation to duration of low dose oxygen therapy
Pil Sang Lee, Jae Won Choi, Sang Geel Lee
Clin Exp Pediatr. 2009;52(1):50-55.   Published online January 15, 2009
Purpose : This study aimed to determine the influence of low-dose oxygen (FiO2 <25%) therapy through nasal cannulae on the progress and prognosis of retinopathy of prematurity (ROP) as well as methods of preventing ROP. Methods : Our subjects comprised premature infants (gestation period <37 weeks; birth weight <1,750 g) born in Daegu Fatima Hospital between February 1, 2001 and...
Review Article
Assessment of retinopathy of prematurity (ROP) revisited
Jeong Hun Kim, Young Suk Yu
Clin Exp Pediatr. 2009;52(1):22-27.   Published online January 15, 2009
Retinopathy of prematurity (ROP) is a major cause of blindness that affects premature infants. With advances in neonatology, ROP is likely to emerge as the most serious problem of vision loss in children even in developed countries; such a situation could be called the third epidemic of ROP. However, controversy and uncertainty still surround favorable outcomes of ROP. For successfully...
Original Article
Serum Albumin Concentrations and Clinical Disorders by Gestational Ages in Preterm Babies
Mia Lee, Soo Youn, Baek Keun Lim, Jong Soo Kim
Clin Exp Pediatr. 2005;48(2):148-153.   Published online February 15, 2005
Purpose : The aim of this study was to determine the reference ranges of serum albumin levels depending on the gestational ages of preterm infants. We also intended to compare the mean serum albumin levels between groups of preterm infants that did not develop clinical disorders later, and groups that did develop clinical disorders such as respiratory distress syndrome, intraventricular...
A Clinical Study for the Time of Development and Risk Factors of Retinopathy of Prematurity
Eun Ae Park, Gyoung Hee Kim
Clin Exp Pediatr. 1997;40(7):945-954.   Published online July 15, 1997
Incidenceand Risk Factorsof the Retinopathy of Prematurity
June Dong Park, Jung Hae Kweon, Woong Heum Kim, Beyong Il Kim, Jung-Hwan Choi, Chong Ku Yun, Sang In Khwarg, Young Suk Yu
Clin Exp Pediatr. 1996;39(3):326-337.   Published online March 15, 1996
Purpose : Retinopathy of prematurity(ROP) continues to be a serious problem in infants who survived with neonatal intensive care. Nevertheless, there is neither available data about the incidence of ROP which may be the basis of the epidemiology, nor analysis of the risk factors of ROP in Korea. The purpose of this retrospective study was to evaluate the incidence of...
A Clinical Study of retinopathy of Prematurity
Jong Won Lee, Jin Kyung Jung, Ji Hae Kang, Ghee Young Jung, Moo Ung Kim
Clin Exp Pediatr. 1994;37(5):636-641.   Published online May 15, 1994
Among 666 premature infants or low birthweight infants who were admitted in NICU of st. Francisco General Hospital from January 1990 to Jun 1992, 96 infants were diagnosed as retinopathy of prematurity by indirect ophthalmoscope. The result were follows: 1) Among 666 patients, retinopathy of prematurity developed in 96 patients(14.1%) 2) The high incidence was observed in low birthweight and small gestational age. 3)...
Clinical Analysis of Retinopathy of Prematurity
Nam Su Park, Young Myoung Cho, Mu Young Song, Un Jun Hyoung, Jin Oh Lee
Clin Exp Pediatr. 1993;36(11):1562-1569.   Published online November 15, 1993
One hundred eighty infants with oxygen therapy who were under 2,500gm birth weight or under 37 weeks of gestational age, were examined between January 1990 and November 1992. We performed clinical analysis and results were as follows. 1) Fifty six infants(31.3%) were diagnosed as retinopathy of prematurity. 2) The first examination was performed at 2.5 weeks of ife on average, and the...
Risk Factors for Retinopathy of Prematurity (Retrolental Fibroplasia)
Beyong Il Kim, Jung Hwan Choi, Chong Ku Yun, Jae Heung Lee, Son Moon Shin
Clin Exp Pediatr. 1987;30(10):1092-1099.   Published online October 31, 1987
We studied 51 premature babies who were admitted to the N.I.C.U. of S.N.U.H., managed with oxygen with or without artificial ventilation due to respiratory distress, and examined by indirect ophthalmoscopy between April 1, 1982 and March 31, 1986. The results were as follows; 1. Among 51 premature babies, retinopathy of prematurity developed in 12 cases (24%). 2. The high distribution of retinopathy of prematurity was observed in...
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