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Original Article
General Pediatrics
Efficacy of conservative treatment of perianal abscesses in children and predictors for therapeutic failure
Lars Boenicke, Johannes Doerner, Stefan Wirth, Hubert Zirngibl, Mike Ralf Langenbach
Clin Exp Pediatr. 2020;63(7):272-277.   Published online May 15, 2020
Background: The optimal management of perianal abscess in children is controversial.
Purpose: To evaluate the efficiency of conservative treatment of perianal abscess in children and identify parameters that predict therapy failure. Methods: All cases of children younger than 14 years of age with perianal abscesses between 2001–2016 were evaluated. Results: Of the 113 enrolled patients, 64 underwent subsequent surgery for advanced disease (primary...
Radiofrequency catheter ablation of atrioventricular nodal reentry tachycardia in children and adolescents: a single center experience
Myung Chul Hyun
Clin Exp Pediatr. 2017;60(12):390-394.   Published online December 22, 2017

Atrioventricular nodal reentry tachycardia (AVNRT) is less common in pediatric patients than in adult patients. Thus, data for pediatric AVNRT patients are insufficient. Hence, we aimed to analyze the patient characteristics, treatment, and any recurrences in pediatric AVNRT patients.


We reviewed the records of 50 pediatric AVNRT patients who had undergone radiofrequency catheter ablation (RFCA) between January 1998 and December 2016...

Case Report
A pediatric case of relapsed pulmonary alveolar proteinosis despite successful whole lung lavage
Seung Young Jin, Hye Ri Yun, Yun Jung Choi, Jun Dong Park, Jin Tae Kim, Chang Hyun Kang, Young Sik Park, Young Hun Choi, Woo Sun Kim, Dong In Suh
Clin Exp Pediatr. 2017;60(7):232-236.   Published online July 31, 2017

Pulmonary alveolar proteinosis (PAP) is a rare disease in children characterized by intra-alveolar accumulation of surfactant proteins, which severely reduces gaseous exchange. Whole lung lavage (WLL) is the preferred technique for the treatment of severe PAP. Herein, we present a pediatric case of PAP treated with WLL. An 11-year-old boy was admitted with the chief complaint of a dry cough...

Original Article
Evaluation of new American Academy of Pediatrics guideline for febrile urinary tract infection
Da Min Choi, Tae Hoon Heo, Hyung Eun Yim, Kee Hwan Yoo
Clin Exp Pediatr. 2015;58(9):341-346.   Published online September 21, 2015

To evaluate the practical applications of the diagnosis algorithms recommended by the American Academy of Pediatrics urinary tract infection (UTI) guideline.


We retrospectively reviewed the medical records of febrile UTI patients aged between 2 and 24 months. The patients were divided into 3 groups: group I (patients with positive urine culture and urinalysis findings), group II (those with positive urine culture...

Review Article
Growth hormone treatment and risk of malignancy
Hyun-Wook Chae, Duk-Hee Kim, Ho-Seong Kim
Clin Exp Pediatr. 2015;58(2):41-46.   Published online February 28, 2015

Growth hormone (GH) treatment has been increasingly widely used for children with GH deficiencies as the survival rate of pediatric patients with malignancies has increased. Both GH and insulin-like growth factor-I have mitogenic and antiapoptotic activity, prompting concern that GH treatment may be associated with tumor development. In this review, the authors examined the relationship between GH treatment and cancer...

Case Report
A case of idiopathic pulmonary hemosiderosis with seasonal recurrence
Ga Young Kwak, Na Young Lee, Moon Hee Lee, Soo Young Lee, Seung Yun Chung, Jin Han Kang, Dae Chul Jeong
Clin Exp Pediatr. 2009;52(2):256-260.   Published online February 15, 2009
Idiopathic pulmonary hemosiderosis (IPH) is a rare disease affecting mostly children. This disorder is characterized by recurrent episodes of hemoptysis, bilateral diffuse pulmonary infiltrates, and iron-deficiency anemia. An acute fulminant alveolar hemorrhage can be fatal due to respiratory failure, while chronic hemorrhage leads to hemosiderin-laden macrophages and pulmonary fibrosis. Genetic, autoimmune, allergic, environmental, and metabolic mechanisms of pathogenesis have been...
Original Article
Outcome after relapse in childhood and adolescent osteosarcoma : single institution experience in Korea
Yun-Jeong Lee, Hyun-Jae Lee, Dong-Ho Kim, Jung-Sub Lim, Jun-Ha Lee, Kyung-Duk Park, Dae-Geun Jeon, Soo-Yong Lee
Clin Exp Pediatr. 2008;51(1):78-83.   Published online January 15, 2008
Purpose : Osteosarcoma is the most common primary malignant bone tumor in children and adolescents. Although survival rate of osteosarcoma patients has markedly improved, about 20-30% of patients still have a relapse. This study was aimed to find factors that influence postrelapse survival of osteosarcoma in childhood and adolescents. Methods : Between 1985 and 2004, of 461 patients who were diagnosed...
Case Report
A case of hereditary hemorrhagic telangiectasia
Young Seung Lee, Seonguk Kim, Eun Kyeong Kang, June Dong Park
Clin Exp Pediatr. 2007;50(10):1018-1023.   Published online October 15, 2007
Hereditary hemorrhagic telagiectasia (HHT), which is characterized by the classic triad of mucocutaneous telangiectases, arteriovenous malformations (AVMs) and inheritance, is an autosomal dominant disorder. The characteristic manifestations of HHT are all due to abnormalities of the vascular structure. This report deals with the case of a 14-year-old girl with typical features of HHT that include recurrent epistaxis, mucocutanous telangiectases, pulmonary...
Original Article
Statistical Analysis of 1,000 Cases of Kawasaki Disease Patients Diagnosed at a Single Institute
Dae Hwan Hwang, Kyoung Mi Sin, Kyong Min Choi, Jae Young Choi, Jun Hee Sul, Dong Soo Kim
Clin Exp Pediatr. 2005;48(4):416-424.   Published online April 15, 2005
Purpose : To find the risk factors associated with coronory artery lesions, non-responsiveness to intravenous immunoglobulin(IVIG) treatment, and recurrences in Kawasaki disease patients. Methods : We retrospectively analyzed 1,000 Kawasaki disease patients who were admitted to Yonsei University Medical Center from September 1990 to December 2003. We compared between responder and non-responder groups to IVIG treatment as well as between relapsed...
Clinical Characteristics of Recurrent Kawasaki Disease
Hyun Ji Lee, Ae Ra Cho, Hae Soon Kim, Sejung Sohn
Clin Exp Pediatr. 2004;47(8):879-883.   Published online August 15, 2004
Purpose : The purpose of this study is to investigate the clinical manifestations and the risk factors of recurrent Kawasaki disease(KD). Methods : From March 1995 to June 2003, 14 children with recurrent KD in Ewha Womans University Hospital were retrospectively evaluated by reviewing their admission reports. The clinical characteristics, laboratory findings, treatment and complications of the recurrent KD group were...
Outcome after Discontinuation of Antiepileptic Drugs in Well Controlled Epileptic Children - Recurrence and Related Risk Factors
Hyo-Bin Kim, Su Jeong You, Tae-Sung Ko
Clin Exp Pediatr. 2004;47(1):66-75.   Published online January 15, 2004
Purpose : There has been no exact criteria established for when to discontinue antiepileptic drugs (AEDs) in epileptic children who had been well controlled for a long period. This study was undertaken to evaluate the recurrence rate and predictive risk factors of relapse after discontinuation of AEDs in epileptic children who had been seizure-free. Methods : We retrospectively studied 294 children...
Case Report
A Case of Kawasaki Disease of Five Recurrences During 4 Years
Jeong Woo Ryu, Dong Soo Kim, Jong Kyun Lee, Jun Hee Sul, Sung Kyu Lee
Clin Exp Pediatr. 1997;40(9):1293-1296.   Published online September 15, 1997
Kawasaki disease is an acute illness of early childhood, especially less than 5 years of age, characterized by prolonged fever(> 5 days), changes of lips and oral cavity, changes of peripheral extremities, polymorphous skin rash, bilateral conjunctival congestion and acute nonpurulent cervical lymphadenopathy. Usually, the recurrence of Kawasaki disease is not frequent. It is thought that the factors in recurrence of Kawasaki disease was...
Original Article
The Risk Factors related to Recurrent Intussusception by Ultrasonography
Eun sun Yoo, Jeong Wan Seo, Seung Joo Lee
Clin Exp Pediatr. 1996;39(12):1707-1716.   Published online December 15, 1996
Purpose : We investigate the risk factors of recurrence after first intussusception. Methods : We have studied the relationship of the clinical features and ultrasonographic findings and the risk of recurrent intussusception in 97 patients with reduced intussusception including 22 recurrent intussusception who admitted at the department of pediatrics at Ewha Womans University Mok-dong hospital from September 1993 to Feburary 1996. Results...
Clinical Review of Recurrent Kawasaki Disease
Jong Woon Choi, Soon Ki Kim, Byong Kwan Son
Clin Exp Pediatr. 1996;39(8):1139-1145.   Published online August 15, 1996
Purpose : The recurrence of Kawasaki disease has not been considered significant and has not been reported on literatures in Korea. Authors reviewed cases with recurrent Kawasaki disease to get informations about recurrent Kawasaki disease and to know whether there is any factor, if present, that can predict recurrence. Methods : We reviewed and analyzed the hospital records of patients with recurrent Kawasaki disease who...
Prophylactic Effect of Diazepam to Prevent Recurrent Febrile Seiz
Seung Eun Choi, Ki Sik Min, Jong Wan Kim, Kwang Nam Kim, Ki Yang Ryoo
Clin Exp Pediatr. 1995;38(5):685-691.   Published online May 15, 1995
Purpose : The purpose of this study was to investigate efficacy of shortterm diazepam prophylaxis in recurrent febrile seizure. Methods : A total of 107 children admitted to the department of pediatrics, Kangdong Sacred Heart Hospital, Ballym University from 1 July 1991 to 31 December 1992, with their first or recurrent febrile seizures(one or two times), were entered in the study,...
Clinical Studies on Risk Facotrs of Recurrnces after first Febrile Convulsions in Infancies and Early Childhood
Hee Kyung Chun, Hyun Ki Joo, Mi Soo Ahn, Ji Sub Oh
Clin Exp Pediatr. 1994;37(6):786-793.   Published online June 15, 1994
The aim of this study was to evaluate the risk factors of recurrences after their first febrile convulsions in infants and young children. Dlinical studies were made on 187 cases of febrile convulsions who were admitted to the department of pediatrics of Wallace Memorial Baptist Hospital from March, 1990 to December, 1992 1) 63 cases of 187 cases had recurrences after their...
Clinical Study of Febrile convulsion and Factors Related to Recurrence
Jong Gyun Kim, Keon Su Rhee, Young Hun Chung
Clin Exp Pediatr. 1994;37(1):1-8.   Published online January 15, 1994
We have reserched the relationship of their clinical pictures and factors related to the risk of recurrence of 75 patients with simple or complex febrile convulsions, who were admitted to the Department of Pediatrics, Chungnam National University Hospital from January 1987 to July 1991. The 75 patient were followed up and consisted of the 55 patients with initial or non-recurrent...
The Risk of Seizure Recurrence of Pediatric Epileptic Patients While Receiving Anticonvulsant Drugs Treatment
Dae Sung Hwang, Byung Hyun Kim, Kwang Soo Oh, Yeon Kyun Oh, Hyang Suk Yoon, Jong Duck Kim
Clin Exp Pediatr. 1993;36(9):1271-1278.   Published online September 15, 1993
To evaluate the risk and factors associated with seizure recurrence on children with epilepsy while receiving the adequate anticonvulsant treament, we studied 58 patients with newly diagnosed epilepsy who were followed prospectively for a median of 26 months (range 7 to 54). The results were as follows: 1) Forty-four of the 58 patients (75.9%)had recurrence...
A Clinical Study on Febrile Convulsion
Jung Hwan Lee, Ki Hwan Yoo, Yong Sook Hong, Joo Won Lee, Soon Kyum Kim
Clin Exp Pediatr. 1993;36(6):850-857.   Published online June 15, 1993
Although febrile convulsion(FC) is a common clinical entity with a high recurrence rate, no specific factors have been identified to be highly predictive of its recurrence. A total to 114 cases of FC identified during a 28 month period (January, 1989-May, 1991) was analysed. A silght predominance of boys over girls(1.3 to 1.0) was observed. The majority of cases(89.4%) were under 3...
A Clinical Study of Febrile Convulsion and Factors Related to Recurrence.
Soo Gi Kang, Myung Hee Yoon, Hyung Ja Park, Shinna Kim
Clin Exp Pediatr. 1990;33(6):772-779.   Published online June 30, 1990
65 Cases of febrile convulsion were reviewed in terms of their clinical pictures and factors related to their recurrences. Seemingly related factors are: 1) age of first episode: The age of first ipisode was under 12months of age in 11.4% of initial cases and 46.7% of recurrent cases. 2) family history of convulsive disorder: There were family history of convulsive disorder in 23.4% of recurrent cases, compare to...
Recurrent Intussusception in Infants and Children.
In Suck Ryu, Ki Sup Chung
Clin Exp Pediatr. 1989;32(1):34-44.   Published online January 31, 1989
A clinical study of 687 patients including 76 with one or more episodes of recurrent intussusception who had been admítted to Severance Hospital, Yonsei University College of Medicine during the 5 year and 4 month period from Jan. 1982 to Apr. 1987 was made and compared with previous clinical data collected from 1977 to 1981. The results were as follows. 1) The overall recurrence rate...
Febrile Convulsion.
Ja Young Park, Seung Ju Lee, Keun Lee
Clin Exp Pediatr. 1982;25(4):356-362.   Published online April 30, 1982
We have observed the clinical findings and progress of the febrile convulsion in 182 children who were admitted to Ewha Womans University Hospital from 1976 to 1980 1) In sex distribution, the boys (65.4%) outnumbered the girls (34.6%). 2) 88% of the children were under 3 years of age at the first epidsode of the febrile convulsion. 3) There was...
A Clinical Study of Recurrent Intussusception.
Hae Ok Kim, Jae Oh Kim, Jeong Woo Suk, Keun Chan Sohn
Clin Exp Pediatr. 1981;24(12):1173-1184.   Published online December 15, 1981
One hundred and ninty nine patients (215 episodes) of intussusception who had been treated at either department of Pediatrics and General Surgery, National Medical Center during the period of 10 years and 7 months from 1970 to 1980 were collected and analyzed statistically. Sixteen patients (32 episodes) out of 199 patients (215 episodes) had been recurred, which were analyzed clinically...
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