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Review Article
Promising candidate cerebrospinal fluid biomarkers of seizure disorder, infection, inflammation, tumor, and traumatic brain injury in pediatric patients
Seh Hyun Kim, Soo Ahn Chae
Clin Exp Pediatr. 2022;65(2):56-64.   Published online August 23, 2021
· Pediatric cerebrospinal fluid (CSF) components have been extensively evaluated as biomarkers of various neurologic diseases.
· Several promising candidate CSF biomarkers, including Tau, glial fibrillary acidic protein, neuron-specific enolase, S100β, and interleukins, have been studied in pediatric patients with seizure disorders, central nervous system infections, inflammation, tumors, hypoxic-ischemic encephalopathy, traumatic brain injuries, intraventricular hemorrhage, and congenital hydrocephalus.
· Circulating microRNAs in the CSF are a promising class of biomarkers for various neurological diseases.
Original Article
Effects of clarithromycin treatment in scrub typhus in children: comparison with chloramphenicol and azithromycin
Min Lee, June Kim, Dae Sun Jo
Clin Exp Pediatr. 2017;60(4):124-127.   Published online April 25, 2017

Chloramphenicol and tetracycline are not recommended for treating scrub typhus in pediatric patients because of potential side effects, such as aplastic anemia or tooth discoloration. While clarithromycin has recently been used in adults, few reports have been published on its effects in pediatric patients. We report the clinical profiles of pediatric scrub typhus and the effects of clarithromycin on scrub...

Selective embolization of the internal iliac arteries for the treatment of intractable hemorrhage in children with malignancies
Sul Hee Bae, Dong Kyun Han, Hee Jo Baek, Sun Ju Park, Nam Kyu Chang, Hoon Kook, Tai Ju Hwang
Clin Exp Pediatr. 2011;54(4):169-175.   Published online April 30, 2011

Acute internal hemorrhage is an occasionally life-threatening complication in pediatric cancer patients. Many therapeutic approaches have been used to control bleeding with various degrees of success. In this study, we evaluated the efficacy of selective internal iliac artery embolization for controlling acute intractable bleeding in children with malignancies.


We retrospectively evaluated the cases of 6 children with various malignancies (acute lymphoblastic...

Review Article
Acute renal failure in pediatrics
Hyewon Hahn
Clin Exp Pediatr. 2007;50(10):948-953.   Published online October 15, 2007
Acute renal failure is the generic term for an abrupt and sustained decrease in renal function resulting in retention of nitrogenous and non nitrogenous waste product. This may results in life threatening consequences including volume overload, hyperkalemia, and metabolic acidosis. Acute renal failure is both common and carries high mortality rate, but as it is often preventable, identification of patients...
Original Article
Clinical Analysis of the Pediatric Patients Seen in the Emergency Medical Center
Hee Jung Lee, So Yoon Park, Young Hwan Lee, Byung Soo Do, Sam Bum Lee
Clin Exp Pediatr. 2005;48(10):1061-1067.   Published online October 15, 2005
Purpose : We studied a clinical analysis of pediatric patients who visited the emergency medical center of Yeungnam University Hospital to compare the characteristics of pediatric emergency patients after year 2000 with the previous studies. Methods : We reviewed 7,034 children under the age of 15 years who visited the emergency medical center of Yeungnam University Hospital during the 2...
Subclavian Catheterization in the Pediatric Patients
Seung Hee Lee, Sung Ho Cho, Keun Mo Kim, Chan Jong Kim, Hoon Kook, Tai Ju Hwang
Clin Exp Pediatr. 1997;40(3):368-374.   Published online March 15, 1997
Purpose : Central venous catheters are used to deliver antibiotics, chemotherapeutic agents, and parenteral nutrition for a extended period of time as well as to draw samples in immunocompromised patients to minimize the discomfort with sampling and the risk of introducing infections. Hickman/Broviac catheters or implantable devices have been used in pediatric patients. This study is aimed to evaluate the safety and clinical efficacy of...
Stastical Studies on Pediatric Emergency Room Patients
Kyoung Dug Moon, Won Ah Park, Hae Kyung Lee, Young Hee Yu, Hyun Suk Lee
Clin Exp Pediatr. 1993;36(12):1732-1739.   Published online December 15, 1993
The authors reviewed 3145 pediatric patients who visited the emergecy room in the hospital during 3yrs period from Jan. 1989 to Dec. 1991. 1) Among the patients visiting the emergency room, the patients under 15 years of age were 26.4% (3145) of total emergency patients (11930). 2) Yearly distribution of patients were decreased 17% between 1989 and 1991. 3) Monthly distribution of visits...
The Gastrofiberscopic Findings in Pediatric Patients
Yong Min Chung, Hwa Ja Kim, Hann Tchah, Sang Kyu Park, Ho Jin Park
Clin Exp Pediatr. 1993;36(6):837-841.   Published online June 15, 1993
We observed 240 cases ranging in age from 3 months to 15 years seen by gastrofiberoscopy in the department of pediatrics of Seoul Red Cross Hospital from March 1990 to October 1992 and following results were obtained. 1) The male to female ratios in total cases and 89 patients complaining of abdominal pain for more than one month were 0.94:1 and...
Clinical and Statistical Studies on Pediatric Emergency Room Patients.
Myoung Soo Chang, Mi Ja Yoon, Kang Oh Lee, Shin Na Kim
Clin Exp Pediatr. 1988;31(1):86-92.   Published online January 31, 1988
The authors reviewed 630 pediatric-age patients who visited emergency room in Dong-Boo City Hospital during 2-year period from Jan. 1985 to Dec. 1986. The results were as follows: 1) The patients under the 15 years of age were 11.4% of total emergency room patients and male to female ratio was 2:1. 2) The patients between 12 years and 15 years of age occupied 28.5% of all pediatric...
Statistical Study on Pediatric Emergency Room Patients.
Hwa Young Kim, Yong Tai Suh, Young Yun Choi
Clin Exp Pediatr. 1984;27(4):378-383.   Published online April 30, 1984
The authors surveyed 17,511 pediatric patients among total 67,290 ones who visited the emergency rodm of Chonnam National University Hospital during the 5 year period from Jan. 1, 1978 to Dec. 31, 1982. 1)70% of total pediatric patients consisted of injury and poisoning, infectious diseases and diseases of the respiratory system. 2)About one-fifth of total pediatric patients was true emergency which...
Clinical Observations on Chief Complaints of Pediatric Patients.
Kang Hyun Cho
Clin Exp Pediatr. 1982;25(2):113-128.   Published online February 28, 1982
The following results were obtained from the clinicostatical observations on chief complaints of pediatric patients at National Medical Center in Seoul during the period from Jan. 1975 to Dec. 1979. 1. Total number of admission during the 5 year period were 3831 and male to female ratio was 1.73:1. 2. Annual incidence : a gradual increase was observed in number...
Review Article
The change of perspective on brain death, euthanasia and withdrawal of the life supporting medical treatments in Korea for pediatric patients
Ivo Kwon
Clin Exp Pediatr. 2009;52(8):843-850.
A recent High Court's decision regarding the withdrawal of life supporting medical treatment (artificial ventilator) from an elderly female patient in the terminal stage has opened up a new era of the "euthanasia dispute" in Korea. With this decision, the legitimate withdrawal of life supporting treatment became possible under certain conditions and the Korean Medical Association is working toward the establishment of practical...
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