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- Neonatology (Perinatology)
- Practice for preterm patent ductus arteriosus; focusing on the hemodynamic significance and the impact on the neonatal outcomes
- Jin A Lee
- Clin Exp Pediatr. 2019;62(7):245-251. Published online April 8, 2019
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Hemodynamically significant preterm patent ductus arteriosus (PDA) affects mortality; comorbidities such as necrotizing enterocolitis, intraventricular hemorrhage, and bronchopulmonary dysplasia; and adverse long-term neurodevelopmental outcomes in preterm infants, particularly in very low birth weight infants. However, recent studies have indicated that there is no consensus on the causal relationship between PDA and neonatal outcomes, the benefit of PDA treatment, the factors...
- Original Article
- Cardiology
- Outcomes of transcatheter closure of ductus arteriosus in infants less than 6 months of age: a single-center experience
- Gwang-Jun Choi, Jinyoung Song, Yi-Seul Kim, Heirim Lee, June Huh, I-Seok Kang
- Clin Exp Pediatr. 2018;61(12):397-402. Published online September 19, 2018
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Purpose: Transcatheter device closure of patent ductus arteriosus (PDA) is challenging in early infancy. We evaluated PDA closure in infants less than 6 months old. Methods: We performed a retrospective review of infants less than 6 months of age who underwent attempted transcatheter device closure in our institution since 2004. To compare clinical outcomes between age groups, infants aged 6–12 months...
- Neonatology (Perinatology)
- Individualized ibuprofen treatment using serial B-type natriuretic peptide measurement for symptomatic patent ductus arteriosus in very preterm infants
- Jeonghee Shin, Eun Hee Lee, Jee Hyun Lee, Byung Min Choi, Young Sook Hong
- Clin Exp Pediatr. 2017;60(6):175-180. Published online June 22, 2017
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Purpose Plasma level of B-type natriuretic peptide (BNP), an emerging, sensitive, and specific biomarker of hemodynamically significant patent ductus arteriosus (PDA), rapidly decreases in infants receiving cyclooxygenase inhibitors for ductal closure. We investigated the usefulness of serial BNP measurement as a guide for individual identification of early constrictive responses to ibuprofen in preterm infants with symptomatic PDA (sPDA).
Methods Before March 2010, the...
- Cardiology
- Correlation of B-type natriuretic peptide levels and echocardiographic parameters in preterm infants with patent ductus arteriosus
- Hyun Ah Jeong, Jeonghee Shin, Eunji Kim, Eun Hee Lee, Byung Min Choi, Chang Sung Son, Joo Won Lee
- Clin Exp Pediatr. 2016;59(4):183-189. Published online April 30, 2016
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Purpose This study aimed to evaluate the correlation, according to postnatal age, between plasma B-type natriuretic peptide (BNP) levels and echocardiographic parameters for the assessment of patent ductus arteriosus (PDA) in preterm infants with respiratory distress.
Methods We enrolled 42 preterm infants with respiratory distress who underwent serial echocardiographic evaluation with simultaneous plasma BNP measurements until ductal closure. The correlations between BNP levels...
- Transcatheter closure of small ductus arteriosus with amplatzer vascular plug
- Eun Hyun Cho, Jinyoung Song, I-Seok Kang, June Huh, Sang Yoon Lee, Eun Young Choi, Soo Jin Kim
- Clin Exp Pediatr. 2013;56(9):396-400. Published online September 30, 2013
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Purpose The purpose of this study was to share our experience of transcatheter closure of small patent ductus arteriosus (PDA) by using an Amplatzer vascular plug (AVP).
Methods We reviewed the medical records of 20 patients who underwent transcatheter closure at Samsung Medical Center and Sejong General Hospital from January 2008 to August 2012. The size and shape of the PDAs were evaluated...
- Case Report
- PHACE association with intracranial, oropharyngeal hemangiomas, and an atypical patent ductus arteriosus arising from the tortuous left subclavian artery in a premature infant
- Do-Hyun Kim, Jang Hwan Choi, Jung Ha Lee, Hee Sup Kim
- Clin Exp Pediatr. 2012;55(1):29-33. Published online January 31, 2012
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PHACE association is a rare neurocutaneous condition in which facial hemangiomas associate with a spectrum of posterior fossa malformations, arterial cerebrovascular anomalies, cardiovascular anomalies, and eye anomalies. We reported a case of PHACE association in a premature infant showing facial, intracranial, and oropharyngeal hemangiomas with evidence of the Dandy-Walker variant and complicated cardiovascular anomalies, including a right-sided aortic arch and...
- Original Article
- Clinical outcome of transcatheter closure of patent ductus arteriosus in small children weighing 10 kg or less
- Young A Park, Nam Kyun Kim, Su-Jin Park, Bong Sic Yun, Jae Young Choi, Jun Hee Sul
- Clin Exp Pediatr. 2010;53(12):1012-1017. Published online December 31, 2010
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Purpose Transcatheter closure has become an effective therapy in most patients with patent ductus arteriosus (PDA). However, there are difficulties in transcatheter closure of PDA in small children. We reviewed clinical outcomes of transcatheter closure of PDA in children weighing less than 10 kg in a single center.
Methods Between January 2003 and December 2009, 314 patients with PDA underwent transcatheter closure in...
- Delayed closure effect in preterm infants with patent ductus arteriosus
- Hyun Ju Lee, Gyu Hong Sim, Kyung Eun Jung, Jin A Lee, Chang Won Choi, Ee Kyung Kim, Han Suk Kim, Beyong Il Kim, Jung-Hwan Choi
- Clin Exp Pediatr. 2008;51(10):1065-1070. Published online October 15, 2008
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Purpose : This study aims to determine whether early closure (within 7 d) of significant patent ductus arteriosus (PDA) with indomethacin or ligation reduces neonatal morbidity when compared with delayed closure (after 7 d). Methods : Fifty-eight extremely-low-birth-weight infants admitted to the NICU of Seoul National University Hospital from April 2005 to May 2007 with PDA were studied retrospectively. Results :... -
- The pharmacological treatment of patent ductus arteriosus in premature infants with respiratory distress syndrome: oral ibuprofen vs. indomethacin
- Soo Jin Lee, Ji Young Kim, Eun Ae Park, Sejung Sohn
- Clin Exp Pediatr. 2008;51(9):956-963. Published online September 15, 2008
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Purpose : Indomethacin is widely used for the prophylaxis and treatment of patent ductus arteriosus (PDA); however, it is associated with side effects such as renal failure, intraventricular hemorrhage, and gastrointestinal bleeding. Intravenous ibuprofen has been shown to be as effective as indomethacin in prompting PDA closure. If treatment with oral ibuprofen is as effective as indomethacin, it would have... -
- The effect of restricted fluid intakes in the first week of life on the risk of bronchopulmonary dysplasia and patent ductus arteriosus in very low birth weight infants
- Hoe Kyoung Koo, Eun Na Choi, Ran Namgung, Min Soo Park, Kook In Park, Chul Lee
- Clin Exp Pediatr. 2007;50(6):536-542. Published online June 15, 2007
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Purpose : We investigated the effects of restricted fluid in the first 7 days of life on the risk of bronchopulmonary dysplasia (BPD) or patent ductus arteriosus (PDA) in very low birth weight (VLBW) infants. Methods : Eighty three VLBW infants who lived more than 28 days were selected. The amount of daily maintenance fluid was determined by calculation of insensible... -
- Case Report
- A case of congenital ductus arteriosus aneurysm
- Sheng Wen Wang, Ji Eun Kim, Young Seok Lee, Young Ah Lee
- Clin Exp Pediatr. 2006;49(12):1363-1366. Published online December 15, 2006
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Aneurysmal dilatation of the ductus arteriosis has been considered a rare but potentially fatal abnormality. The mechanism of ductal aneurysmal formation remains uncertain. Plain chest radiography has proven helpful in the diagnosis of ductus arteriosus aneurysm (DAA), before the application of transthoracic echocardiography. The transthoracic echocardiography is an important tool for the diagnosis and follow-up of DAA. We present a... -
- Original Article
- The effects of ibuprofen and indomethacin therapy for patent ductus arteriosus in preterm infants
- Wooksun Choi, Jung-Yeon Shin, Byung Min Choi, Baik-Lin Eun, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee
- Clin Exp Pediatr. 2006;49(12):1315-1323. Published online December 15, 2006
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Purpose : This study was conducted to compare the efficacy and safety of ibuprofen and indomethacin in the treatment of patent ductus arteriosus (PDA) in preterm infants and to determine whether ibuprofen can be an alternative drug. Methods : A total of 32 preterm infants with symptomatic PDA were enrolled in the study. Twelve infants received intravenous ibuprofen 10 mg/kg, followed... -
- Effect of prophylactic indomethacin in extremely low birth weight infants
- Bo Lyun Lee, Su Jin Kim, Soo Hyun Koo, Ga Won Jeon, Yun Sil Chang, Won Soon Park
- Clin Exp Pediatr. 2006;49(9):959-965. Published online September 15, 2006
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Purpose : The purpose of this study was to investigate the effect of prophylactic indomethacin on reduction of patent ductus arteriosus(PDA) and intraventricular hemorrhage(IVH) in extremely low birth weight infants(ELBWI). Methods : Retrospective review of 84 ELBWI who were admitted to our neonatal intensive care unit from June 2004 to April 2006 was performed. Patients were divided into prophylactic group(n=28) and... -
- Impact of Device Evolution in Transcatheter Closure of Patent Ductus Arteriosus Using Duct-Occlud Coils : Comparison of Mid-term Results
- Myung Kwan Kim, Dong Ki Han, Jae Young Choi, Yuria Kim, Byung Won Yoo, Deok Young Choi, Jun Hee Sul, Sung Kue Lee
- Clin Exp Pediatr. 2005;48(2):158-164. Published online February 15, 2005
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Purpose : We reviewed the therapeutic results of various Duct-Occlud coils(pfm AG, K ln, Germany) to evaluate the efficacy of the most-recently modified Duct-Occlud coil(Nit-Occlud) in the transcatheter closure of patent ductus arteriosus(PDA), including large defects more than 4 mm in diameter. Methods : Two hundred and five patients who underwent percutaneous PDA occlusion using Duct- Occlud devices from March... -
- Comparison of Clinical Courses According to the Existence of Patent Ductus Arteriosus in Respiratory Distress Syndrome
- Ju Hee Seong, Hyeon Joo Lee, Hyun Kee Hong, Chong-Woo Bae, Yong-Mook Choi
- Clin Exp Pediatr. 2003;46(11):1080-1084. Published online November 15, 2003
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Purpose : To compare perinatal characteristics, clinical courses, and overall morbidity between respiratory distress syndrome(RDS) with patent ductus arteriosus(PDA) and RDS without PDA in neonates. Methods : Eighty-three neonates who were diagnosed and treated for RDS in the neonatal intensive care unit(NICU) from Jan. 2000 to Dec. 2002 were included in this study. RDS was complicated with PDA(group A) in... -
- A Comparative Study of the Effects of Intravenous Indomethacin and Oral Mefenamic Acid in the Treatment of Premature Infants with Patent Ductus Arteriosus
- Hae Jung Park, Yoon Suk Jung, Nam Soo Kim, Chang Ryul Kim, Hyuk Kim, Soo Jee Moon
- Clin Exp Pediatr. 2001;44(1):32-39. Published online January 15, 2001
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Purpose : For the management of patent ductus arteriosus(PDA) in premature infants, fluid restriction, correction of anemia, mechanical ventilation, diuretics, and surgery have been used, and the closure rate of PDA has improved significantly since the introduction of indomethacin and mefenamic acid as pharmacologic treatments of PDA. We studied to evaluate and compare the therapeutic effects of indomethacin and mefenamic... -
- Case Report
- Three Cases of Hemolysis After Transcatheter Closure of A Patent Ductus Arteriosus
- Sang-Bum Lee, Myung Chul Hyun
- Clin Exp Pediatr. 2000;43(10):1399-1403. Published online October 15, 2000
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Severe hemolysis occurred after transcatheter occlusion of a patent ductus arteriosus in 3 patients among 41 patients who underwent transcatheter occlusion of a patent ductus arteriosus. The problems were managed by a standard surgical ligation of the duct, leaving the occlusion device(the Rashkind umbrella and a detachable coil) in situ in one patient, surgical removal of the detachable coil and... -
- Original Article
- Transcatheter Closure of the Patent Ductus Arteriosus
- Young A Lee, Myung Chul Hyun, Sang Bum Lee
- Clin Exp Pediatr. 2000;43(9):1200-1206. Published online September 15, 2000
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Purpose : Transcatheter closure of the patent ductus arteriosus(PDA) is a well-established, effective therapeutic modality, and many kinds of devices have been used to perform this closure. The aim of this study is to compare the effects of different kinds of devices. Methods : We reviewed retrospectively the charts of 43 patients who were admitted to Kyungpook University Hospital between June... -
- Usefulness of Plasma Atrial Natriuretic Peptide Concentration in the Diagnosis of Patent Ductus Arteriosus in Preterm Infants
- Byung Min Choi, Jae Kyun Yoon, Hyun Hee Lee, Hae Won Cheon, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
- Clin Exp Pediatr. 2000;43(7):897-904. Published online July 15, 2000
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Purpose : Diagnosis of a hemodynamically significant patent ductus arteriosus(PDA) that should be treated is difficult to determine by clinical and echocardiographic examinations. The aim of this study was to clarify the interrelationship of plasma atrial natriuretic peptide(ANP) concentrations and clinical signs or echocardiographic signs of PDA in preterm infants and use plasma ANP concentrations as a diagnostic indicator of a hemodynamically significant PDA. Methods... -
- Study on Closing Time after Indomethacin Administration in Prematurity with Patent Ductus Arteriosus
- Wan Cho, Suk Min Choi, Kyu Hyung Lee
- Clin Exp Pediatr. 1999;42(11):1508-1515. Published online November 15, 1999
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Purpose : In the clinical field, the closing time of patent ductus arteriosus(PDA) varies among patients after indomethacin administration. We tried to predict it by analyzing related factors, and also by understanding what affects it. Methods : Among 30 cases of PDA at the NICU, 24 cases(male 14 cases, female 10 cases) were selected. Fifteen cases closed early(within 36 hours) and... -
- Case Report
- A Case of Pulmonary Artery Sling Associated with Left Bronchial Stenosis and Patent Ductus Arteriosus
- Woo Suk Juhng, Myung Hee Han, Chan Uhng Joo
- Clin Exp Pediatr. 1998;41(10):1417-1423. Published online October 15, 1998
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Pulmonary artery sling is a rare and potentially lethal vascular anomaly wherein the anomalous left pulmonary artery arises from the posterior aspect of the right pulmonary artery and passing to the left lung between the trachea and the esophagus which causes respiratory distress in infants and children due to the extrinsic compression of the airway by the anomalous vessel. Associated... -
- Original Article
- Comparison of Treatment Course and Outcome between Medically and Surgically Treated Patent Ductus
- Jeong Geun Kim, Jeong Nyun Kim, Dong Chul Park, Shin Yeong Lee, Hyun Chul Lee, Myung Jae Chey, Churl Young Chung,
- Clin Exp Pediatr. 1998;41(10):1334-1341. Published online October 15, 1998
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Purpose : Early intervention is needed to treat patent ductus arteriosus(PDA) as it is a major cause of increased mortality in preterm infants. However, it is uncertain which is better, medical versus surgical management. We reviewed medical records to compare the treatment course and outcome between medically and surgically treated preterm PDA infants. Methods : Thirth-two Mechanically ventilated pretem infants(gestational age<34... -
- Effects of Patent Ductus Arteriosus on Right Ventricle in Premature Infants : by M-mode and Doppler Echocardiography
- Eun Jeung Kim, Eun Sil Lee, Young Hwan Lee, Son Moon Shin, Jeong Ok Hah
- Clin Exp Pediatr. 1998;41(6):734-740. Published online June 15, 1998
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Purpose : Patent ductus arteriosus, derived left to right shunt flows, elevate the pulmonary artery pressure in infants and children and may alter right ventricular afterload thereby right ventricular function. Therefore, we examined the effects of patent ductus arteriosus on the right ventricular systolic time interval in premature infants by non-invasive Doppler echocardiography. Methods : Tweleve premature infants with patent ductus arteriosus were studied... -
- Comparison of Continuous versus Intermittent Infusion of Indomethacin in PDA of Preterm Infants
- Yun Kyoung Lee, Hee Seok Kim, Kyoung Ran Park, Chan Hu Park, June Dong Park, Beyong Il Kim, Woong Heum Kim, Jung Hwan Choi, Chong Ku Yun
- Clin Exp Pediatr. 1998;41(5):599-605. Published online May 15, 1998
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Purpose : Patent ductus arteriosus(PDA) of prematurity is very important disease to study because it causes many cases of perinatal morbidity and its incidence is now increasing. Nowadays indomethacin is the drug of choice for PDA closure, but its use has been limited due to its side effects. Therefore, we compared the effect and side effects of indomethacin according to... -
- Comparison of Continuous Versus Intermittent Infusion of Indomethacin in PDA of Preterm Infants
- Yun Kyoung Lee, Hee Seok Kim, Kyoung Ran Park, Chan Hu Park, June Dong Park, Beyong Il Kim, Woong Heum Kim, Jung Hwan Choi, Chong Ku Yun
- Clin Exp Pediatr. 1998;41(4):464-470. Published online April 15, 1998
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Purpose : Patent ductus arteriosus(PDA) of prematurity is very important disease to study because it causes many cases of perinatal morbidity and its incidence is now increasing. Nowadays indomethacin is the drug of choice for PDA closure, but its use has been limited due to its side effects. Therefore, we compared the effect and side effects of indomethacin according to the infusion method, continuous... -
- Percutaneous Closure of Patent Ductus Arteriosus Using Coil Embolization
- Mi Jung Kang, Sejung Sohn, Eun Jung Bae, In Seng Park, Seong Ho Kim
- Clin Exp Pediatr. 1998;41(3):369-377. Published online March 15, 1998
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Purpose : Percutaneous closure with occluding coils has been recently described as a method of nonsurgical treatment of the small patent ductus arteriosus(PDA). The snare-assisted technique or detachable coil has been newly developed, improving coil delivery and eliminating the incidence of coil embolization. This method is also applicable to residual PDA following surgical ligation or device implantation. The study purpose... -
- Nonoperative Treatment of PDA Using the Duct-OccludⓇ
- Dong Woon Shin, Kyung Hee Lee, Heon-Seok Han
- Clin Exp Pediatr. 1997;40(5):635-640. Published online May 15, 1997
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Purpose : Among the several transcatheter devices of PDA occlusion, Rashikind device was the most extensively experienced, but it had risk of occluder embolism and incomplete occlusion of PDA, approximately 27%. The authors used Duct-OccludⓇ, made of 0.028 inch stainless steel coil. The coil is double cone-shape in released state, and used in streched condition through 4F implantation catheter for... -
- Midterm Result after Transcatheter Occlusion of Patent Ductus Arteriosus with Rashkind PDA Umbrella Device
- Chung Il Noh, Eun Sook Han, Ho Sung Kim, Jung Yun Choi, Yong Soo Yun
- Clin Exp Pediatr. 1995;38(5):668-674. Published online May 15, 1995
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Purpose : To evaluate the appropriateness of the transcatheter occlusion with Rashkind um-brella occlusion device Methods : Among the 54 cases who had been tried transcatheter closure of patent ductus ar teriosus from January, 1992 till December, 1993 at Seoul National Univerity Children's Hospital, the first follow-up evaluation with Doppler echocardioram were done in 43 cases at the mean i-nterval of... -
- Case Report
- A Case of Patent Ductus Arteriosus with Eisenmenger Syndrome Treated by Ligation of PDA
- Chang Seon Yoo, Hae Yong Lee, Mee Kyung Namgoong, Jong Soo Kim, Mee Yon Cho, Joong Hwan Oh
- Clin Exp Pediatr. 1995;38(2):257-263. Published online February 15, 1995
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We experienced a case of eisenmenger syndrome treated by simple surgical intervention. Eisenmenger syndrome refers to patients with congenital heart defects who have a systemic level of pulmonary arterial pressure and high pulmonary vascular resistance, with right-to-left or bidirectional shunting. Because a progressive rise in pulmonary vascular resistance may be better tolerated with an intracardiac communication, surgical repair in such patients... -
- Original Article
- The Mitral Regurgitation in Patent Ductus Arteriosus (PDA)
- Hyang Suk Yoon, Soon Ho Choi
- Clin Exp Pediatr. 1994;37(3):317-321. Published online March 15, 1994
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Mitral regurgitation (MR) was analyzed by Doppler echocardiography, preoperatively and postoperatively, in 59 patients with patent ductus arteriosus (PDA). The ratio of left atrial dimension and aortic root dimension (LAD/LOD) and the maximal velocity of the mitral valve (MV max) were compared in pre, postop group. The degree of the regurgitation was given to the MR group. In preop MR... -
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6.52022CiteScore92nd percentilePowered by
